Tropical Journal of Natural Product Research (TJNPR)

Tropical Journal of Natural Product Research (TJNPR) is the official scientific publication of the Natural Product Research group, University of Benin; and it is available in both printed and electronic formats. The journal is published monthly.

Tropical Journal of Natural Product Research (TJNPR) is a peer-reviewed, open access online international journal which publishes original research papers. The journal welcomes submission from scholars and experts for possible publication from all over the world. The scope of the journal includes: Pharmaceutical research, chemistry and biochemistry of naturally occurring compounds, biological evaluation of crude extracts, ethnomedicine, traditional and complementary medicine, ethnopharmacology, biomedical research, Biotechnology, Evaluation of natural substances of land and sea and of plants, microbes and animals, pharmacognosy, bioavailability, clinical, pharmacological, toxicological studies and pharmacokinetics of phytochemicals, Isolation and characterization of compounds, structure elucidation, synthesis and experimental biosynthesis of natural Product as well as developments of methods in these areas are welcomed in the journal. Finally, research papers in fields on the chemistry-biology boundary, papers discussing the screening of natural Product for biological activity against different health targets are also encouraged.

Vol. 8 No. 11 (2024): Tropical Journal of Natural Product Research (TJNPR)

Published: 2024-12-02

The Pharmacological and Nutritional Properties of Rosmarinus officinalis: A Comprehensive Review

Abdelhay Benyaich, Mustapha Aksissou

8945-8954

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DOI: https://doi.org/10.26538/tjnpr/v8i11.1

Functional Use of Lactic Acid in Food Fermentation: Overview, Current Trends and Future Perspectives

Olubukola Oziegbe, Joy I. Azeta, Yemisi D. Obafemi

8955 – 8966

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DOI: https://doi.org/10.26538/tjnpr/v8i11.2

Fermented Fruits in Asia: Fermentation Process, Microbes, and Health Benefits

Elvin S. Dikkuruse, Siti F. Sabran, Fazleen I.A Bakar, Mohd F.A. Bakar, Furzani Pa’ee, Norhayati Muhammad

8967 – 8987

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DOI: https://doi.org/10.26538/tjnpr/v8i11.3

Effect of Moringa oleifera Leaf Extract on TGF-β1 and Galectin-3 Levels and Cardiac Fibrosis in Diabetic Rat

Suryono Suryono, Muhammad I. Amien, Achmad I. Tohari, Antonius D. Saputra, Muhammad R. F. Hidayat, Hazbina F. Ramadhan

8988 – 8992

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DOI: https://doi.org/10.26538/tjnpr/v8i11.4

Antiplatelet and Antithrombotic Properties of 2-Geranyl-2',3,4,4'-tetrahydroxydihydrochalcone, A Chalcone from Artocarpus altilis (Park.) Fosberg Leaves

Nanang Fakhrudin, Gharsina Ghaisani Yumni, Farah Azura Salsabila, Candra Adianto, Wilda Priskila Iriani Saragi, Yuli Widiyastuti, Arief Nurrochmad, Sitarina Widyarini, Subagus Wahyuono

8993 – 8997

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DOI: https://doi.org/10.26538/tjnpr/v8i11.5

Chemical Characterization and Effects of Oral Administration of Pelargonium graveolens Essential Oil on Testicular Histomorphometry of White Rabbits

Meriem Kasdi, Lynda Lakabi, Ferroudja Medjdoub-Bensaad, Samira Akdader

8998 – 9003

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DOI: https://doi.org/10.26538/tjnpr/v8i11.6

Evaluation of Antioxidant, Anti-Inflammatory, and Anti-Ulcer Activities of Yellow Apple (Malus domestica Borkh) Ethanol Extract from Algeria

Saliha Djidel, Amel Bouaziz, Nihed Barghout, Assia Bentahar, Saliha Dahamna, Seddik Khennouf

9004 – 9009

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DOI: https://doi.org/10.26538/tjnpr/v8i11.7

Chemical Composition, Biological Activities, and Docking Studies of Essential Oil from Eupatorium odoratum L. Collected in Dak Lak, Vietnam

Truong N. Ngu, Dam T. B. Hanh, Phan V. Trong, Phan H. T. Bao, Nguyen T. T. Hien, Nguyen Q. My, Do V. Huy, Dang T. T. My, Hieu P. C. Truong, Khuyen T. H. Pham, Dao C. To

9010 – 9018

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DOI: https://doi.org/10.26538/tjnpr/v8i11.8

Morchella esculenta (L.) Pers. Wild of the Province of Taza, Morocco: Ethnomedicinal and Socio-Economic Survey and Perspectives

Asmae Mahtal, Fatima Lamchouri, Hamid Toufik

9019 – 9026

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DOI: https://doi.org/10.26538/tjnpr/v8i11.9

In vitro Anti-inflammatory and Anti-allergenic Effects of Thai Herbal Formula and its Isolates, Rhinacanthin-C and Rhinacanthin-N in RBL-2H3 Cells and RAW264.7 Macrophages

Natta Choedchutirakul, Sumalee Panthong, Intouch Sakpakdeejaroen, Pakakrong Thongdeeying, Atchanika Taingthum, Aumpol Bunpean

9027 – 9034

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DOI: https://doi.org/10.26538/tjnpr/v8i11.10

Investigating the Effects of the Ethyl Acetate Fraction of Mas Banana Bracts: Suppressing Cell Growth, Promoting Cell Death, and Targeting Specific Molecules in Hela Cells

Riska H. Putri, Soetrisno, Brian Wasita, Heru Priyanto, Eti P. Pamungkasari, Risya Cilmiaty

9035 – 9042

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DOI: https://doi.org/10.26538/tjnpr/v8i11.11

Ameliorative Effects of Calcium-Based Supplements on Monosodium Glutamate-Induced Organ Injury in Rats

Aniebiet U. Essien, Abidemi Eludire, Emmanuel O. Odungide, Damilola O. Peters, Israel S. Afolabi

9043 – 9049

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DOI: https://doi.org/10.26538/tjnpr/v8i11.12

Synthesis, Characterization, and Anticancer Evaluation of Thiourea Benzamide Derivatives and their Cu(II) and Pt(IV) Complexes Against PC3 and HepG2 Cancer Cell Lines

Abedalhusaeen R. Al-Ameertaha, Rafid H. Al-Asadi

9050 – 9060

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DOI: https://doi.org/10.26538/tjnpr/v8i11.13

Caraway (Carum carvi L.) Agro-industrial Waste; Anti-obesity Effect and Chemical Characterization

Saleh H. El-sharkawy, Yasser S. Elfarhaty, Ahmed S. Saad, Nebal D. El Tanbouly, Amira S. El Senousy

9061 – 9072

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DOI: https://doi.org/10.26538/tjnpr/v8i11.14

Toxicity Studies of Abutilon crispum and Indigofera prostrata Whole Plants on Wistar Rats

Kuchi Manjeera, Raja Sundararajan

9073 – 9078

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DOI: https://doi.org/10.26538/tjnpr/v8i11.15

In Silico Study of the Antidiabetic Effect of Ethyl Acetate Fraction of Banana Bract in Diabetic Rats

Hardono Hardono, Soetrisno Soetrisno, Bambang Purwanto, Brian Wasita, Ida Nurwati, Eti P. Pamungkasari

9079 – 9085

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DOI: https://doi.org/10.26538/tjnpr/v8i11.16

Methods for Quantification of Tannins and Other Polyphenols in Syzygium cumini (L.) Bark for Potential Use in Leather Tanning Colouration

Gilmar K. Henar, Olayinka Oderinde, Gerda Wesenhagen, Nykieta A. James, Fauz Sawirjo, Dayo A. Ayeni, Olubunmi A. Ogundiran

9086 – 9096

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DOI: https://doi.org/10.26538/tjnpr/v8i11.17

β- Hematin and Nitric Oxide Inhibitory Activities of Ten Nigerian Medicinal Plants

Gbemisola M. Ojobaro, Abraham O. Nkumah, Saka Y. Alabi, Thomas Abu. Zainab A. Molik, Omonike O. Ogbole

9097 – 9103

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DOI: https://doi.org/10.26538/tjnpr/v8i11.18

Comparative Cytotoxicity and Green Synthesis of Silver Nanoparticles from Sansevieria cylindrica

Andhavarapu V. S. K. Bhavani, Annammadevi G Sayam

9104 – 9110

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DOI: https://doi.org/10.26538/tjnpr/v8i11.19

Assessment of Acute and Sub-Acute Toxicity of Muskmelon Pectin on Wistar Rats Model

Thakur Rekhabai, Santosh R. Kumar

9111 – 9114

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DOI: https://doi.org/10.26538/tjnpr/v8i11.20

Assessment of the Antiplasmodial and Haematoprotective Potential of a Polyherbal Extract of Azadirachta indica, Mangifera indica, and Persea americana Leaves in Mice Infected with Plasmodium berghei

Israel E. Ebhohimen, Reward Agbamuche, Emmanuel O. Eromosele, Emmanuel O. Eromosele, Onosolesena D. Idiakheua

9115 - 9120

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DOI: https://doi.org/10.26538/tjnpr/v8i11.21

Gas Chromatography-Mass Spectrometry Analysis and Antimalarial Activity of Salix ledermannii Ethanol Leaves Extracts

Alexander F. Nanven, Nanvyat Nannim, Etuh A. Monday, Samson Mark, Nwibari B.M. Wilson, Dawet Anthony

9121 - 9130

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DOI: https://doi.org/10.26538/tjnpr/v8i11.22

Annona muricata L. Fruit Pulp Improves Hormone Profile and Semen Quality in Testosterone-Induced Benign Prostatic Hyperplasia Male Rats

Rutherford I. Esiaba, Jasper U. Nwoko, Chukwudi E. Ukachukwu, Celestine N. Ekweogu, Mercylyn E. Uche, Eziuche A. Ugbogu

9131 - 9137

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DOI: https://doi.org/10.26538/tjnpr/v8i11.23

Pectin-Starch Biocomposite Reinforced with Rattan-Derived Cellulose Nanocrystals: A Study of Mechanical and Water Absorption Properties

Muhammad T.A. Fath, Halimatuddahliana Nasution, Hamidah Harahap, Gina C.R. Hasibuan, Vikram Alexander

9138 - 9144

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DOI: https://doi.org/10.26538/tjnpr/v8i11.24

Medicinal Plants Species Most Commonly Sold by Herbalists in the Province of Marrakech, Morocco

Hanane Azalmad, Abha C. Hassani, Mouna Ameggouz, Otman El-Guourrami, Anass Doukkali, Hanane Benzeid

9145 - 9154

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DOI: https://doi.org/10.26538/tjnpr/v8i11.25

In Vitro Studies of Biosynthesized Nanoparticles of Dysphania Aqueous Leaves Extract Against Some Isolated Bacteria from Wounds and Burns and In Silico Evaluations of Compounds Identified in its GC-MS Spectra

Ekhlas Q. Jasim, Munther A. Muhammad-Ali , Amani A. Al-Abdullah

9166 - 9173

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DOI: https://doi.org/10.26538/tjnpr/v8i11.26

Anti-inflammatory, Analgesic, and Motor Improvement Effects of Bee Venom Acupuncture on Freund’s Complete Adjuvant-Induced Spinal Degeneration in Rats

Nguyen N. Mau, Le V. Quan, Pham V. Du, Tran V. Thanh, Nghiem H. Thanh, Nguyen B. Quang, Pham H. Van, Nguyen V. Tan, Can V. Mao

9166 - 9173

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DOI: https://doi.org/10.26538/tjnpr/v8i11.27

Chemical Composition, In vivo Antihelmintic, and Acute Toxicity Studies of Buchholzia coriacea Engler (Capparaceae) Seed Extract

Chinomso P. Amaefula, Onuchi M. Mac-kalunta, Julian I. Iheanyichukwu, Chinedum I. Nwankwo, Ngozi K. Achi, Innocent O. Abaleke, C. Friday, Obinna A. Igwe, Kalu K. Igwe, Ifeanyi E. Otuokere

9174 - 9178

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DOI: https://doi.org/10.26538/tjnpr/v8i11.28

Effect of Phoenix reclinata Jacq Methanol Leaf Extract and Fractions on Plasmodium berghei Infected Mice

Paul Chinwuba, Peter A. Akah, Chukwuemeka S. Nworu, Chimaobi O. Ugorji, Ike C. Jeremiah

9179 - 9185

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DOI: https://doi.org/10.26538/tjnpr/v8i11.29

Studies on the Effect of Musa paradisiaca on the Morphology and Microanatomy of Some Female Reproductive Organs of Animal Model

Kebe E. Obeten, Baron Bwanga, Elliot Bufuku Kafumukache, Okimba A. Adams, Etah Etah Nkanu

9186 - 9191

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DOI: https://doi.org/10.26538/tjnpr/v8i11.30

Physical and Chemical Compatibility Testing of Intravenous Phenytoin Preparations In 0.9% Normal Saline Solution

Erna P. Ningrum, Fita Rahmawati, Marlyn D. Laksitorini, Endang Lukitaningsih

9192 - 9198

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DOI: https://doi.org/10.26538/tjnpr/v8i11.31

Anti-hyperlipidemic Effect of Camellia hakodae Ninh Extract in an In Vivo Rat Model

Ngo T. M. Binh, Nguyen H. Ngan, Do T. H. Lan, Nguyen H. Hanh, Nguyen T. H. Tuan

9199 - 9205

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DOI: https://doi.org/10.26538/tjnpr/v8i11.32

Molecular Docking of Phytochemicals from Vernonia amygdalina and Nauclea latifolia as Potential Inhibitors of Drug Targets in Ascaris lumbricoides

Janet F. Akinseye, Uba D. Somtochukwu, Sunday A. Buru, Bernard O. Oluboyo, Adebimpe H. Egbebi, Agu C. Chidera, Thomas H. Zagi

9206 - 9214

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DOI: https://doi.org/10.26538/tjnpr/v8i11.33

Chemical Constituents and Antioxidant Activity of Ultrasonication-Assisted Aqueous Extract of Pumpkin (Cucurbita moschata) Seeds

Erinda N. Pratiwi, Soetrisno, Bambang Purwanto, Yulia L.R. Dewi, Eti P. Pamungkasari, Brian Wasita

9215 - 9218

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DOI: https://doi.org/10.26538/tjnpr/v8i11.34

Anti-Inflammatory Activity of Qutsh Al Hindi (Saussurea lappa) Root Fractions: In Vitro Assay and Characterization of its Active Compound

Sukmawati, Ida Musfiroh, Muchtaridi Muchtaridi, Adryan Fristiohady, Nur Kusaira Khairul Ikram

9219 - 9223

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DOI: https://doi.org/10.26538/tjnpr/v8i11.35

In-Vivo Study on the Hair Growth-Enhancing Effects of CTUMP’s Herb Shampoo

Nguyen T.L. Tuyen, Nguyen T.T. Linh, Le T.C. Thuy, Pham T.T. Lien

9224 - 9230

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DOI: https://doi.org/10.26538/tjnpr/v8i11.36

Chemical Composition, Antibacterial, Antioxidant, and Toxicity Profiles of Cajuput Oils from Diverse Malaysian Districts

Musa Isah, Wan Abdul Wahab Wan-Nor-Amilah, Nurin A. Sallehudin, Mohamad N. Azmi, Mohd D. Sul’ain

9231 - 9237

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DOI: https://doi.org/10.26538/tjnpr/v8i11.37

The Effects of Phenylpropanoid and Aurone Compounds on Cell Cycle Modulation and Apoptosis Induction in 4T1 Breast Cancer Cells

Rollando Rollando, Eva Monica, F.X. Haryanto Susanto, Ellyvina Setya Dhini

9238 - 9244

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DOI: https://doi.org/10.26538/tjnpr/v8i11.38

Growth Pattern and Cardiovascular Response of Japanese Quails to the Administration of Parquetina nigrescens Leaf Extracts

Adeyinka O. Akintunde, Lois C. Ndubuisi-Ogbonna, Aderiike G. Adewumi, Olufunso E. Akinboye, Oluwaseun A. Adewole, Samuel I. Akeju, Oluwaseyi E. Ogundipe, Rufus O. Animashaun

9245 - 9255

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DOI: https://doi.org/10.26538/tjnpr/v8i11.39

Formulation Development and Skin Evaluation of Gel-Based Cream Containing Tamarind Gum

Meyli Phuy, Chiravut Pathumthanasup, Mukda Chitcharoenthum, Surapon Saensouk, Theera Rittirod, Watcharee Khunkitti, Pathomthat Srisuk

9256 - 9264

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DOI: https://doi.org/10.26538/tjnpr/v8i11.40

Anti-Inflammatory and Analgesic Activities of Aqueous Extracts from Stigma maydis: In Silico and In Vivo Investigations

Andri Tilaqza, Merlita Herbani, Anwar, Iif Hanifa Nurrosyidah

9270 - 9280

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DOI: https://doi.org/10.26538/tjnpr/v8i11.41

Effects of Three Modified Starches on The Physicochemical Properties of Chitosan-Based Packaging Film

Nguyen Minh Chau, Tran Quang Hieu, Duong Duc Vuong, Tran Nhut Hoa, Nguyen Thi Ai Van, Nguyen Duc Vuong

9281 - 9286

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DOI: https://doi.org/10.26538/tjnpr/v8i11.42

Antinociceptive and Anti-inflammatory Activities of Jatropha tanjorensis Leaf Extract in Mice

Uchenna B. Alozieuwa, Michelle E. Inagbor, Theresa O. Ozoude, Olajumoke O. Nwaechefu

9287 - 9291

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DOI: https://doi.org/10.26538/tjnpr/v8i11.43

Cytotoxicity with Brine Shrimp Lethality Test, Antibacterial Activity, and Dipeptidyl Peptidase IV (DPP IV) Inhibitory Activity of Red Betel (Piper cf. arcuatum Blume) Stem Extract

Candra Irawan, Andita Utami, Ismail, Ratna K. Putri, Imalia D. Putri, Jenny A. Tambunan

9292 – 9295

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DOI: https://doi.org/10.26538/tjnpr/v8i11.44

Green synthesis of Characterized Bio-functionalized ZnO Nanoparticles from Terminalia catappa (Almond) Methanol Leaf Extract and their Potential Antioxidant and Antibacterial Properties

Johnson O. Momoh, Sanjeev Kumar, Oluremi N. Olaleye, Oluwasegun M. Adekunle, Taiwo S. Aiyelero

9296 - 9309

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DOI: https://doi.org/10.26538/tjnpr/v8i11.45

Assessing Genetic Diversity in Squash Pumpkin (Cucurbita moschata) through Computational Analysis of Plastid Genes

Uduak L. Edem, Aniefiok N. Osuagwu, Ndem E. Edu, Lasbrey I. Emeagi, Reagan B. Agbor, Nne-Ese N. Nsungo, Ukam U. Uno, Ekerette E. Ekerette

9310 - 9314

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DOI: https://doi.org/10.26538/tjnpr/v8i11.46

Phytosynthesis and Antibacterial Activity of Silver Nanoparticles of Aqueous Extracts of Gandaria (Bouea macrophylla G.) Leaves and Stem Bark

Catherina M. Bijang, Shielda N. Joris, Nurani Hasanela, Nelson Gaspersz, Ajot Waremra

9315 - 9321

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DOI: https://doi.org/10.26538/tjnpr/v8i11.47

Antinutrients Properties and Antioxidant Activity of Some Nigerian Leafy Vegetable Plants

Faith C. Ogbonnaya, Gogonte H. Amah, Babafemi T. Ogunbiyi, Ngozi A. Ukangwa, Oluwaseun A. Adewole, Lois O. Oladele, Emmanuel O. Akani

9265 - 9269

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DOI: https://doi.org/10.26538/tjnpr/v8i11.48

ERRATUM: Animal Model Assessment of HELLP Syndrome during Treatment with Methanol Plant Extracts of Jatropha curcas, Alchonnea cordifolia, and Secamone afzelii

Kenneth Atoe, Macdonald Idu, Beckley Ikhajiagbe, Adewale G. Bakre, Oluwafemi Adeyemi, S A. Omenai, Harrison O. Egbo, Sunday E. Omozuwa, Oghenevwogaga O. Edenya

9322 - 9329

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DOI: https://doi.org/10.26538/tjnpr/v8i11.49

ERRATUM: Polysaccharides from the Fruits of Balanites aegyptiaca Del.: Preliminary Characterization, Antioxidant, Hypoglycaemic, and Anti-inflammatory Activities

Malika Seddiki, Mohammed D. Ould El Hadj, Ahmed Messai-Mohamed, Zakaria Boual, Hakim Belkhalfa, Youcef Rahmani, Philippe Michaud

9330 - 9338

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DOI: https://doi.org/10.26538/tjnpr/v8i11.50

ERRATUM: Effects of Mackerel Scad Collagen Gel on Superficial Non-Infected Wound in Mice

Elisa Herawati, Nafira Saraswati, Tetri Widiyani

9339 – 9345

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DOI: https://doi.org/10.26538/tjnpr/v8i11.51

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