Vol. 9 No. 5 (2025): Tropical Journal of Natural Product Research (TJNPR)

Articles

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  Okoubaka aubrevillei; Occurrence, Myth, Ethno-Medicinal Properties, and Other Uses; Mini Review

  David G. Oke, David O. Adekunle, Idowu A. Obisesan

  1889 – 1893

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  Connecting the Dots between Gut Microbiota Dysbiosis and Atherosclerosis: A Systematic Review

  Muhammad Syukri, Aisyah Elliyanti, Andani E. Putra, Mohammad S. Rohman, Muhamad Fakhri

  1894 – 1900

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  Chemical Constituents and Antifungal Potential of Combined Essential Oils of the Leaves of Coleus barbatus and Corymbia citriodora Growing in Tanzania against Skin Fungal Pathogens

  Ramadhani S. O. Nondo, Francis Machumi, Alfredi A. Moyo, Juma I. Juma, Pax J. Masimba

  1901 – 1908

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  Analgesic and Anti-inflammatory Activity of Ethanol Extract from Cocoa Pod Husk

  Fifteen A Fajrin, Diana Holidah, Ika P Dewi, Fransiska M Christianty, Dwi K Pratoko, Mutiara DP Kinanti, Nurika A Fadhilah, Rosalina A Kusuma, Arinal Haq, Rafika Istidamah

  1909 – 1917

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  Ficus deltoidea Ethanol Extract Cytotoxic Activity on MCF-7 Treated Doxorubicin: An In Silico and In vitro Approach

  Rizky C Putri, Kusmardi, Rani W Hakim, Aditya E Nurfitrah

  1918 – 1923

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  Standardisation of Fermented Uncaria nervosa Bark Extract as an Anti-Acne Gel Preparation

  Maria Almeida, Angga C Narsa, Sri AF Kusuma, Sriwidodo Sriwidodo

  1924 – 1932

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  Development and Validation of Purple Sweet Potato (Ipomea batatas L.) Pigment as a Titrimetric Indicator for Hydrochloric Acid Quantification

  Maria A.U. Leba, Anselmus B. Baunsele, Sisilia D.B. Mau, Maximus M. Taek, Noemia A. Ruas, Adilson D. C. Ruas, Maria B. Tukan, Erly G. Boelan, Faderina Komisia

  1933 – 1938

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  Effect of Orange (Citrus sinensis) Peels Enriched Feed on Meat Quality and Antioxidant Status of Fed Broiler Chicken

  Tosin B. Oboh, Samuel Aro, Idowu S. Oyeleye, Olajide R. Ojo, Ayokunle O. Ademosun, Olufemi O. Adu, Ganiyu Oboh

  1939 – 1944

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  Novel Clean Label Approach: Assessment of Antimicrobial Potential of Combined Use of Aromatic and Medicinal Plants and Bacteriocin against Salmonella enterica, Bacillus cereus and Staphylococcus aureus in Model Sausages

  Meryem Bouraqqadi, Abdeljalil Ait Arbain, Laila Manni, Wifak Bahafid, Samir Ananou

  1945 – 1952

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  Sedative and Anti-convulsant Activities of Methanol Extract of an African Edible Mushroom

  Kizito E. Bello, Dina Yamin, Abdirasak S. Ali-Mude, David A. Zakari, Obeimen C. Stella-Maris, Itodo K. Janefrances, Osazuwa O. Christopher, Egbeja T. Idris, Hadiza O. Abdulsalam, Okpanachi M. Abdubala, Audu A. Godwin, Dorathy A Ogohi, Maji O. Okpanachi, Momoh B. Theophilus

  1953 – 1957

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  Phytochemical Constituents, Antioxidant and Anti-inflammatory Potentials of Dechlorophyllized Extract of Kenikir Leaves (Cosmos caudatus Kunth)

  Zainal Abidin, Aminah, Rais Razak, Mamat Pratama

  1958 – 1963

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  Exploring the In Vitro Anti-Inflammatory Effect and In Silico Toxicity Profile of Curcuma aeruginosa Roxb. Extract in RAW 264.7 Macrophages

  Defiona RNAzerlyn, Dinia R Dwijayanti, Masruri Masruri, Nashi Widodo

  1964 – 1972

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  Anti-Dermatophytic Potentials of Garcinia kola and Vernonia amygdalina Extracts

  Henrietta Obi, Ogechukwu Dozie-Nwakile, Somtochukwu Ewuzie, Ifeanyi Okeke, Angus Oli, Calistus Nwakile

  1973 – 1976

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  A Comparative Study on the Effectiveness of Pepper Leaves Tea and Chamomile Tea for Insomnia Disorder: A Single-Blind Randomized Clinical Trial

  Siriporn Jarukitsakul, Thapanee Keawjeen, Kochakorn Inthanuchit, Bodin Chatawatee, Chonlada Masapan, Sirada Chaisri, Kanyarat Pakbara, Thanyaluck Siriyong

  1977 – 1980

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  Anticancer Activity of Mackerel Scad (Decapterus macarellus) Fish Oil on Colorectal Cancer Cell Lines

  Pipin Agnesia, Elisa Herawati, Rarastoeti Pratiwi

  1981 – 1987

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  Flavonoids Extracts from Hunteria umbellata Seeds Modulates Streptozotocin-Induced Diabetes and Hepatic Complications in Rats

  Elijah Odesanmi, Omotade Oloyede, Olorunfemi Molehin, Deborah Jesusanmi 

  1988 – 1995

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  Formulation of Facial Clay Mask from Red Glutinous Rice (Oryza sativa L. var. glutinosa) Bran Extract

  Fitria Nugrahaeni, Anisa Amalia, Fathiyah Rohmah

  1996 - 2001

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  The Potential of Single Bulb Garlic Fermented with Lactobacillus plantarum B1765 to Manage Gluconeogenesis and Inflammation in Type-2 Diabetes Mellitus Rats

  Prima R. Wikandari, Nuniek Herdyastuti, Tukiran, First A. Wati, Shod A. Dzulkarnain

  2002 – 2006

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  Antihyperglycemic and Anti-inflammatory Effects of African parquetina Leaf in Streptozotocin-Induced Diabetes in Rats

  Temidayo Ogunmoyole, Yetunde E. Akanni, Iyanu J. Asejire, Adenike O. Adefila

  2007 – 2013

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  Preliminary Pharmacognostic Studies and Diuretic Evaluations of Crude Aqueous Extract of Monodora myristica (Gaertn.) Dunal (Annonaceae) Seeds on Wistar Rats

  Emmanuel O Ikpefan, Lawrence U. Nwankwo, Chinwendu P. Eze

  2014 – 2023

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  Antioxidant and Anti-Obesity Potentials of Moringa oleifera Roots in High-Fat Diet-Induced Obesity in Rats

  Marhaen Hardjo, Surahmat Hamid, Nurfaiqa Hardjo, Sukaeni Ibrahim, Ilhamuddin Azis, Mirna Muis, Syahrijuita Kadir

  2024 – 2029

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  Macaranga tanarius Reduces the Expression of Vascular Endothelial Growth Factor and Tumor Necrosis Factor-Alpha in Diabetic Retinopathic Rats

  Amalia E. Putri, Wimbuh T. Widodo, Lyna L. Indrayati, Tri A. Sari, Alvi Z. Nisak, Prisca O. Wulandari, Rifkarosita P. Ginaris, Sri B.S.M.K. Negara, Afidatul Muadifah

  2030 – 2038

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  Inhibition of Cetylpyridinium Chloride against the Growth of Porphyromonas gingivalis

  Ernie M. Setyawatie, Irma J. Savitri, Nova A. Hepitaria, Ferlina DAYP Asano, Gusti IA Agung Putra, Esi Y. Fitrina, Rizka Valentina

  2039 – 2042

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  Antirheumatic Potential of Araucaria-Derived Biflavonoids through In Silico Docking to 20S Proteasome

  Luthfan Irfana, Chinesia P. Suryawan, Budi Arifin, Suminar S. Achmadi, Setyanto T. Wahyudi, Purwantiningsih Sugita

  2043 – 2053

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  Lycopene Ameliorates Brain Oxidative Stress and Exhibits Antidepressant, Antianxiety, and Motor Coordination-Enhancing Effects in Rats via Increased Serotonergic Transmission

  Sohrab A. Shaikh, Kho Q. Thing, Jerusha Aruputhanathan, Chuah C. Hua

  2054 – 2060

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  Antioxidant Potentials of Terminalia catappa Seed Extract and Metformin on the Liver and Kidney of Diabetic Wistar Rats

  Catherine IO Ukam, Ugochukwu G Jidere, Josephine E. Egbung, Magdalene Obiabang, Daniel E Uti, Item J Atangwho, Godwin E Egbung

  2061 - 2066

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  Amelioration of Paraquat-Induced Hippocampal Damage and Cognitive Impairment by Selenium and Magnesium in Mice

  Stephen K. Abisoye, Airat A. Bakare, Ademola A. Oremosu, Onyeka A. Okafor, Theresa T. Afolabi, Edem E. Edem

  2067 - 2073

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  Crude Drug Standardization and Antioxidant Properties of an Indonesian Antidiabetic Polyherbal Formulation and Plant Constituents

  Dwi Hartanti, Muhammad F. Romdhoni, Alwani Hamad

  2074 - 2080

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  Justicia gendarussa Gel Film: A New Approach to Alleviating Upper Back Muscle Pain

  Aumpol Bunpean, Natta Choedchuthirakul, Nattakridta Changjaroen, Suthida Thila, Aphichaya Suwanphosri, Intouch Sakpakdeejaroen

  2081 – 2085

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  Antioxidant and Anti-Hypercholesterolemia Activities of Bohadschia vitiensis Extract In vitro and In vivo

  Andi Mu’nisa, Andi Irma Suryani, Kusdianawati, Andi Muflihunna

  2086 – 2091

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  Investigating the Multifaceted Therapeutic Potential of Firmiana colorata (Roxb.) R.Br. Leaf Extract: A Natural Remedy to Pain, Fever, and Oxidative Stress

  Mahabuba K. Shorna, Md K. Hossain, Ummah T. Nisat, Sayeda S. Didari, Sarah W. Jannat, Sumaiya Akbar, Saima S. Alam, Aninda K. Nath

  2092 – 2099

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  Anti-trypanosomal and hepato-toxicity potentials of Lantana camara (Verbenaceae) leaf extracts in albino rats challenged with Trypanosoma brucei

  Ebele A. Orji, Christian T. Orji, Chiemekam S. Ezechukwu, Simeon I. Egba

  2100 – 2105

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  Ameliorative Potential of Nigella sativa (Black Seed) Ethanol Extract on Monosodium Glutamate-Induced Ovarian Damage in Sprague-Dawley Rats

  Mahmud O. Aminu, Ini-Ibehe E. Okoko, Sulayman A. Salaudeen, Taiwo O. Kusemiju, Abayomi O. Okanlawon

  2106 - 2111

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  Assessment of Antibacterial Activity and Toxicity of Mentha spicata, Mentha piperita, and Mentha pulegium Essential oils

  Rayan Arrahmouni, Chadia Ouazzani, Azzedine Er-Ramly, Abdellah Moustaghfir, Mouna Ameggouz, Farah Aabouch, Otman El-Guourrami, Hasnaa Sadik, Abdallah Dami, Lhousaine Balouch

  2112 - 2117

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  Antibacterial Activity of Compounds Identified from the Active Fractions of Secang Wood (Caesalpinia sappan)

  Angriani Fusvita, Sernita, Firdayanti, Sri Aprilianti Idris, Agung Wibawa Mahatva Yodha, Muhammad Azdar Setiawan, Arfan, Wahyuni, Sahidin

  2118 - 2124

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  Response Surface Methodology for Optimization of Free Fatty Acid Glycerolysis in Crude Palm Oil Using Crude Glycerol

  Nanda Suriaini, Normalina Arpi, Yanna Syamsuddin, Muhammad Supardan

  2125 - 2130

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  Comparative Effect of Fluoxetine and Imipramine on Social Defeat Stress Model of Depression in Mice

  Festus Avwotuhwaye, Festus Avwotuhwaye, Anthony Eduviere, Celestine Akpovwre, Demaki Winifred, Akinsola Olubiyi, Micheal Kadiri, Wesley Edobo

  2131 - 2140

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  Enhancing analgesic and anti-inflammatory synergetic effect with Naringenin: In-silico and in vivo investigation

  Ravina Barve, Kiran Kotade, Sangita Bhandare, Mayur Gaikar, Vikrant Dhamak

  2141 - 2148

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  Effect of Active Fraction of Physalis angulata Extract on p53, mRNA of CYP11A1, 17β-HSD3, FSHR, and MTA2 expressions on testes of Streptozotocin-induced Diabetic Rats

  Saddam Muhdi, Rul Syarif, Dicky Rizal, Mae SH Wahyuningsih, Nur Arfian, Ika Rahayu, Frida Tavia, Muhamad Tolib, Kim Syafeti

  2149 - 2153

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  Acquisition of Vermiwash from Eudrilus eugeniae and Its Influence on the Post-Germination Growth of Mustard Greens

  Oanh Huynh, Tien T T Le, Thu TA Dao, Phuc T Vo

  2154 - 2158

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  Immunostimulant Effect of Combination Extract of Garcinia mangostana, Moringa oleifera, and Phyllantus niruri based on Phagocytic Index and Titre Antibody Production in Mice

  Tanti Sujono, Maryati Maryati, Ambar Nugraheni, Andi Suhendi, Farhan Yanuarsyah, Em Sutrisna, Arifah Wahyuni, Yohana Selviana, Syochi Dewi

  2159 - 2166

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  In-Silico Molecular Docking and ADMET Prediction of Natural Compounds In Oncom

  Irma Kartika, Azhar Syach, Diajeng Larasati, Shabrina Pitaloka, Sheila Octaviany, Fera Kurniadewi, Hanhan Dianhar, Irwan Saputra, Muktiningsih Nurjayadi, Rika Syaadah, Irah Namirah

  2167 - 2176

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  Integrated Bioinformatics and Docking Study on Phenolic Compounds for Targeting Hypoxia-Associated Genes in Preeclampsia

  Dwi Suryandari, Raden Muharam, Aryo Tedjo, Fadilah Fadilah

  2177 – 2182

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  Anti-obesity Activity of Chlorophyll a from Spirulina (Arthrospira platensis) Through the Inhibition of Pancreatic Lipase Enzyme

  Ika Maharani, Athika Putri, Ririn Saharsanti, Lia Kusmita

  2183 – 2190

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  Anti-diabetic Effect of Ethyl acetate Extract of Spondias mombin (Linn) Stem Bark in Streptozotocin-Induced Diabetic Rats

  Damilola Omoboyowa, Temitope Aribigbola, Olayemi Fagbomedo, Ayomide Oni

  2191 - 2197

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  Comprehensive Bibliometric Analysis of Curcumin Research: Trends and Developments from 1937 to 2025

  Lian Pajrıantı, Annisa A. Ghifari, Eka Bebasari, Lalu Irham, Wirawan Adikusuma, Darmawi Darmawi, Muhammad Hamidy

  2198 – 2203

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  In Silico ADMET Profiling and Toxicological Evaluation of Sudan IV Dye on Allium cepa (Onions) Root Meristems

  Gbenga Alege, Opeyemi Ayorinde, Olabanjo Ifatimehin, Suleiman Alakanse, Enifome Adams, Amina Musa, Ruth Fanwo, Mariam Sani, Monday Yakubu

  2204 - 2213

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  Optimization of Extraction of Volatile Compounds from Cinnamomum camphora (L.) J. S. Presl Leaves Using Microwave-Assisted Hydro-Distillation Method

  Nguyen Thanh, Mai Khanh, Doan Dung, Phan TK Phung, Ho Quang

  2214 - 2219

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  Unveiling the Evolutionary History and Structural Dynamics of Dioscorea bulbifera L. and Congeners through matK Gene In silico Analysis

  Uduak Edem, Aniefiok Osuagwu, Ndem Edu, Reagan Agbor, Lasbrey Emeagi, Chineke Oluwatobi, Ukam Uno, Ekerette Ekerette

  2220 - 2226

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  Phytochemical composition, Antioxidant Activity, and Cytotoxicity of Asystasia gangetica (Linn) T. Anderson Extracts

  Charinya So-In, Thanatcha Pangchai, Phitcharat Sunthamala, Sujira Maneerat, Surasak Khankhum, Nuchsupha Sunthamala

  2227 - 2233

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  The Physical Properties, Structure, and Sensory Characteristics of Cookies Replacing Lotus Seed Flour and Low Glycemic Index Sugar

  Nguyen Thi Mai Huong, Duy H. Truong 

  2234 - 2243

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  Global Multidisciplinary Collaboration in Therapeutic Cannabis Research, Regulatory and Pharmaceutical Challenges

  Abdelhafid Benomar, Mohamed Fekrouni, Amina Moutawalli, Sara Elhoudaibi, Saad `Chakkor, Brahim Mojemmi

  2244 – 2251

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  Safety Profile of Aqueous Extract from Traditional Recipes in the Royal Textbook of King Rama V in Albino Wistar Rats

  Supawadee Trerattanathawan, Teeraporn Katisart, Ampa Konsue

  2252 – 2262

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  Chemical Composition and Biological Activity of Vietnamese Vernonia amygdalina Essential Oil: In Vitro and In Silico Studies

  Truong Ngu, Thi B. H. Dam, Duy Nguyen, Van H. Do, Lan A. Bui, Hieu P. C. Truong, Manh H. Tran, Phi H. Nguyen, Nguyen T. M. Huong, Dao C. To

  2263 – 2270

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  Methanol Leaf Extract of Ricinus communis L. Mitigates Dichlorvos-Induced Cardiac Injury via Anti-Inflammatory, Antioxidant, and Anti-Apoptotic Mechanisms in Wistar Rats

  Waidi A. Saka, Funmilayo M. Moronkeji, Funmilayo M. Akano, Yusuff D. Igbayilola, Lawan J. Hamidu, Muhammed B. Zakari

  2271 - 2278

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  Unveiling the therapeutic potential of Plumeria pudica: GC-MS Analysis, phytochemical insights, and histopathological evaluation for Wound Healing and Anti-Diabetic applications

  Dharmendra Pradhan, Kumar S. Ranajit, Kumar P. Sahu, Sandip Chatterjee

  2279 - 2290

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  Evaluation of In vitro antioxidant and anti-inflammatory prowess of Alchornea Cordifolia aqueous leaf extract

  Mary O. Bishop-Lawrence, Patrick C. Ichipi-Ifukor, Israel O. Okoro, Fidelis I. Achuba

  2291 - 2298

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  Bioprospecting Endophytic Bacteria in Curcuma zedoaria for In Vitro Antioxidant and Anti-inflammatory Potentials

  Linh Chi Tran, Chong Kim Thien Duc, Duy Toan Pham, Trang Thi Xuan Dai, Nguyen Trong Tuan

  2299 - 2306

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  Identification, Morphological Characterization and Distribution of Fusarium species in Moroccan Wheat

  Houda Khalifi, Fatiha Bentata, Mustapha Labhilili, Soukaina Hammoumi, Sanae Karim, Mouaaid Abdelali, Najiba Brhadda, Rabea Ziri

  2307 – 2313

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  In Vitro Analysis of Antioxidant, Antibacterial, and Antifungal Properties of Zingiber officinale, Syzygium aromaticum, Pimenta dioica, and Cinnamomum verum

  Meriem Mabchour, Hanane Bakrim, Sara Boukour, Ouiam El Galiou, Abdelhay Arakrak, Mohammed Khaddor, Amin Laglaoui

  2314 – 2322

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  Effect of a nature-derived combination of Ananas comosus and Bambusa bambos (L.) in hyperlipidemic experimental animals

  Van Anh T. Pham, Phong Pham, Tung Tran, Hien Dang, Quang Trinh, Duong Dau

  2323 - 2328

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  In vitro Immunomodulatory and Hepatoprotective Activities of Selected Indonesian Medicinal Plants

  Widya Wasityastuti, Dwi Nugrahaningsih, Suratno Ratnoglik, Laura Yamani, Chie Aoki-Utsubo, Tutik Wahyuni

  2329 - 2334

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  Phenolic Profile, Antioxidant, and Antibacterial Activities of Extracts and Essential Oils of Algerian Artemisia herba-alba and Thapsia garganica

  Khadidja Dehimi, Djamila Chicouche Hamina, Afaf Hadji, Belkis F. Benchettouh, Hedda Djerarda, Ghania Boussadia, Sarra Bouafia

  2335 - 2340

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  Characterization of Immobilized Endo-Polygalacturonase PGC-AN64 from Aspergillus niger HO32 with Potential Biotechnological Interest

  Nour Eddine Bentouhami , Sondes Mechri, Sara Moumnassi, Meryem Yahyaoui, Ayoub Bekkouch, Houssam Abouloifa, Nabil Ghabbour, Reda Bellaouchi, Abdelkarim Abousalham, Ennouamane Saalaoui, Loubna Firdaous, Marilize Le Roes-Hill, Bassem Jaouadi, Abdeslam Asehraou

  2341 – 2349

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• ERRATUM: Antioxidant Activity and Cardioprotective Potential of Nanoemulsion Mix of Rosmarinus officinalis and Centella asiatica in Gestational Diabetes Mellitus Zebrafish Larvae Model

  Husnul Khotimah, Devi M. Arista, Rizki Amelia, Safrina D. Ratnaningrum, Yahya Irwanto

  2350 - 2356

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• ERRATUM: Evaluation of the α-amylase, α-glucosidase, and tyrosinase inhibitory and photoprotective activities of organic solvent and aqueous Extracts of Retama monosperma stem

  Fatima Zahra Benkhouili, Amina Moutawalli, Hanane Benzeid, Anass Doukkali, Ahmed Zahidi

  2357 – 2363

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