Effects of Cyperus esculentus (Tiger Nut) Extract on the Irradiated Testes of Wistar Rats

doi.org/10.26538/tjnpr/v4i11.20

Authors

  • Benjamin E. Udoh Department of Radiography and Radiological Science, University of Calabar, Calabar, Nigeria
  • Akwa E. Erim Department of Radiography and Radiological Science, University of Calabar, Calabar, Nigeria
  • Samson O. Paulinus Department of Radiography and Radiological Science, University of Calabar, Calabar, Nigeria
  • Eru M. Eru Department of Anatomical Sciences, University of Calabar, Calabar, Nigeria
  • Ekaete V. Ukpong Department of Radiography and Radiological Science, University of Calabar, Calabar, Nigeria
  • Itoro Efanga Department of Radiography and Radiological Science, University of Calabar, Calabar, Nigeria
  • Bassey E. Archibong Department of Radiography and Radiological Science, University of Calabar, Calabar, Nigeria
  • Akpama E. Egong Department of Radiography and Radiological Science, University of Calabar, Calabar, Nigeria
  • Etorobong E. Udo Department of Radiography and Radiological Science, University of Calabar, Calabar, Nigeria
  • Nneoyi O. Egbe Department of Radiography and Radiological Science, University of Calabar, Calabar, Nigeria

Keywords:

Cyperus esculentus, Ionizing irradiation, Testes, Wistar rats

Abstract

Cyperus esculentus (Tiger nut) may be a useful supplement in combating fertility challenges imposed by exogenous substances like ionizing radiation. The study investigated the usefulness of Cyperus esculentus as a phytoremedy supplement in reversing radiation-induced changes on the testicular microstructure of Wistar rats. The animals were exposed to ionizing radiation and treated with tiger nut aqueous extract at 750 mg/kg for 2 hours 7 days post irradiation. The animals were exposed to X-rays using exposure settings of 75 kVp and 20 mAs with a moBDiagno X-ray unit and sacrificed 24 hours after the last administration. Their testes were removed and processed for histological evaluation. The results showed that ionizing radiationcaused deleterious effects on the seminiferous tubules of the rats which were reversed in animals treated with the aqueous tiger nut extract. In conclusion, Cyperus esculentus has the potential to reverse radiation-induced damage on the ultrastructure of the testes, which may improve radiation-related male fertility effects.

References

Budgell GJ, Cowan RA, Hounsell AR. Prediction of scattered dose to the testes in abdominopelvic radiotherapy. Clin Oncol. 2001; 13:120-125.

Wan L, Yeonghoon S, Hyosun J, Min JB, Jungki K, Dongil K, Joong SK. Protective effect of administered rolipram against radiation-induced testicular injury in mice. World J Mens Health. 2015; 33:20-29.

Agarwal A, Mulgund A, Hamada A, Michelle RC. Unique view on male infertility around the globe. Rep Biol Endocrinol. 2015; 13:3-7.

Ombelet W. Global access to infertility care in developing countries: a case of human rights, equity and social justice. F. V.Vin. Obgyn. 2011; 3:257-266.

Ahmed M and Hussain F. Chemical composition and biochemical activity of Aloe vera (Aloe Barbadensis Miller) leaves. Int J Chem Biochem Sci. 2013; 3:29-33.

Adesuyi AO, Awosanya OA, Adaramola FB, Omeonu AI. Nutritional and phytochemical screening of Aloe barbadensis. Curr Res J Biol Sci. 2011; 4:4-9.

Agunbiade OS, Ojezele OM, Ojezele JO, Ajayi AY. Hypoglycaemic activity of Commelina africana and Ageratum conzyzoides in relation to their mineral composition. Afr Health Sci. 2012; 12:198-203.

Okorie SU and Nwanekezi EC. Evaluation of proximate composition and antinutritional factors of Cyperus esculentus (Tiger nut) as influenced by boiling. J Environ Sci Toxicol Food Tech. 2014; 7:70-73.

Achoribo ES and Ong MT. Tiger nut (cyperus esculentus): source of natural anticancer drug? brief review of existing literature. Euromediterranean Biomed J 2017; 12:91-94.

Belewu MA and Belewu KY. Comparative phytochemical evaluation of tiger nut, soya bean and coconut milk. Int J Agric Biol. 2007; 5:785-787.

Maduka N and Ire FS. A review of some prevention strategies against contamination of Cyperus esculentus and tiger nut-derived products of economic importance. Asian J Sci Res Rep. 2019; 3:1-13.

Roselló-Soto E, Garcia C, Fessard A, Barba FJ, Munekata PE, Lorenzo JM, Remize F. Nutritional and microbiological quality of tiger nut tubers (Cyperus esculentus), derived plant-based and lactic fermented beverages. Ferment. 2019; 5,3;https//doi.org/10.3390/fermentation5010003.

Okafor J, Mordi J, Ozumba A, Solomon H, Olatunji I. Preliminary studies on the characterization of contamination in tiger nut (yellow variety). Proceeding of the 27th annual Conference on Nigeria institution of food science and technology, Nigeria, 2003. October 13-17, 210-211.

Umerie SC and Enebeli JN. Malt caramel from nut of Cyperus esculentus. J Biol Res Tech. 1997; 8:215-216.

Yamaguchi M and Kashiwakura I. Role of reactive oxygen species in the radiation response of human hematopoietic stem/progenitor cells. Cell 2013; 8,7; https://doi.org/10.1371/journal.pone.0070503.

Trinidad TP, Mallillin AC, Loyola AS, Sagum RS, Encabo RR. The potential health benefits of legumes as a good source of dietary fibre. Br J Nutr. 2010; 103:569-574.

Teixeira TA, Pariz JR, Dutra RT, Saldiva PH, Costa E, Hallak J. Cut-off values of the Johnsen score and copenhagen index as histopathological prognostic factors for postoperative semen quality in selected infertile patients undergoing microsurgical correction of bilateral subclinical

varicocele. Transl Androl Urol. 2019; 8:346-355.

Surai PF. Silymarin as a natural antioxidant: an overview of the current evidence and perspectives. Antioxidants. 2015; 4:204-247.

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Published

2020-11-01

How to Cite

Udoh, B. E., Erim, A. E., Paulinus, S. O., Eru, E. M., Ukpong, E. V., Efanga, I., … Egbe, N. O. (2020). Effects of Cyperus esculentus (Tiger Nut) Extract on the Irradiated Testes of Wistar Rats: doi.org/10.26538/tjnpr/v4i11.20. Tropical Journal of Natural Product Research (TJNPR), 4(11), 966–969. Retrieved from https://tjnpr.org/index.php/home/article/view/964