Anti-Inflammatory Activity of KNC, a Vietnamese Herbal Medicine Prescription on RAW 264.7 Cells doi.org/10.26538/tjnpr/v4i11.14
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Abstract
Kinh-Nghiem-Canh (KNC) is a herbal priscription drug used for the treatment of musculoskeletal pain in the Vietnamese oriental medicine. The anti-inflammatory effect of KNC decoction in lipopolysaccharide (LPS)-treated RAW 264.7 cells was evaluated using LISA test kits for detection of inflammatory mediators PGE2 and proinflammatory cytokines such as TNF-α, IL-1β, and IL-6. Results showed that anti-inflammatory properties of KNC resulted from the inhibition of nitric oxide (NO) production, prostaglandin E2 (PGE2) release, and other proinflammatory cytokines such as IL-1????, TNF-????, and IL6 in a RAW 264.7 macrophage cell line.
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