Preliminary Phytochemical Evaluation and In Vitro Xanthine Oxidase Inhibitory Activity of Balanophora subcupularis P.C. Tam and Balanophora tobiracola Makino (Balanophoraceae)
doi.org/10.26538/tjnpr/v3i1.2
Keywords:
Balanophora subcupularis,, Balanophora tobiracola,, xanthin oxidase,, TLC.Abstract
Balanophora subcupularis P.C. Tam and Balanophora tobiracola Makino are two new recently recorded species of the genus Balanophora J.R. Forst and G. Forst in Viet Nam. In the present work, we investigated the phytochemical component, in vitro xanthine oxidase (XO) inhibitory activity of methanol extracts, fractions (n-hexane and ethyl acetate) and water residue of these two species. The Thin layer chromatography (TLC) of the methanol extracts and fractions of the two species were also done. The Ethyl acetate fractions of the two species showed the best XO inhibitory activity with IC50 values of 48.41 ± 1.56 µg/mL and 11.87 ± 1.28 µg/mL for B.
subcupularis and B. tobiracola, respectively. The results show that the ethyl acetate fractions of the two Balanophora species may serve as a potential source of bioactive constituent for use in the treatment of gout.
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