A Review of the Phytochemistry and Pharmacology of Lannea species

doi.org/10.26538/tjnpr/v2i10.1

Authors

  • Jonathan I. Achika Department of Chemistry, Ahmadu Bello University, Zaria, Kaduna State, Nigeria.

Keywords:

Pharmacology,, Anacardiaceae,, Lannea,, phytochemistry,, antioxidant.

Abstract

The Lannea species belong to the Anacardiaceae family and are widely distributed throughout the world. Members of this species have been used traditionally to treat stomach ache, seminal weakness, excessive seminal emissions, ulcers, sore injuries, dyspepsia, gout, dysentery, sore eyes, leprosy, sprains and bruises, diarrhea, gastritis, rheumatic pain, sterility, scurvy, epilepsy and intestinal helminthiasis and hematochezia. In traditional medicine, some members of this species are used as astringent, while the leaf extract of some plants of this species are used in treating inflammations, sprains and body pain. The juice extracted from the leaves of plants
belonging to this species are taken orally to treat toothache while their stem bark is made into a paste and used to treat body pains. The Lannea species are used as antidote in coma caused by narcotics and to stop bleeding and prevent tetanus. Phytochemical investigations of the Lannea species have revealed that many chemical constituents from this family are highly bioactive.
Although, the medicinal properties of Lannea species are recognized worldwide, there is no review article on the phytochemical constituents and pharmacological activities of the Lannea species. The present paper reviews the medicinal properties alongside with peculiar phytoconstituent, biological activity, isolated compounds and pharmacological activities of various plants of the Lannea species. The medicinal properties of these plants could be attributed to the availability of a broad range of bioactive constituents such as flavonoids, phenolic acids, terpenoids (monoterpenes, sesquiterpenes, diterpenes, and triterpenes) and sterols reported in this
species.

References

Jamshidi-Kia F, Lorigooini Z, Amini-Khoei H. Medicinal plants: past history and future perspective. J Herb Med Pharmacol. 2018; 1:1-7.

Mukherjee PK and Wahile A. Integrated approaches towards drug development from Ayurveda and other Indian system of medicines. J Ethnopharmacol. 2006; 103(1):25-35.

Tene TO, Ngouafong TF, Seukep AJ. Traditional uses, phytochemical and pharmacological profiles, and toxicity of Enantia chlorantha (Oliver): An overview. Edorium J Med. 2016; 3:12–18.

Street RA and Prinsloo G. Commercially important medicinal plants of South Africa: A review. J Chem. 2013;19(1):35-45.

Beaman JH. Allergenic Asian Anacardiaceae. Clin Dermatol. 1986; 4(2):191-203

Burkil HM. The useful plants of West Africa. Family Anchomanes Difformis. 1985; 2nd ed.: Royal Botanic Gardens. Ibadan.

Franco F and Narasimhan D. Plant names and uses as indicators of knowledge patterns. Indian J Trad Knowl. 2009; 8(4):645-647.

Kamalkishor NHN and Kulkarni KM. Fish stupefying plants used by the Gond tribal of Mendha village of Central India. Indian J. Tradit. Knowl. 2009; 8(4):531-534.

Kantamreddi VSSN, Lakshmi YN, Kasapu VS. Preliminary phytochemical analysis of some important Indian Plant species. Ijpbs. 2010; 1(4):456-458.

Mia MMUK, Kadir MF, Hossan MS & Rahmatullah M. Medicinal plants of the Garo tribe inhabiting the Madhupur forest region of Bangladesh. Am.-Eurasian J Sustain Agric. 2009; 3(2):165-171.

Kumar RB. Flora of sacred groves at Sriharikota island, Andhra Pradesh, India. Ethnobotanical Leaflets. 2010;(4)5:234-236.

Dinesh V. Traditional uses of plants in indigenous folklore of Nizamabad District, Andhra Pradesh, India. Ethnobotanical Leaflets. 2010; (1):5-8.

Upadhyay B, Dhaker AK, Kumar A. Ethnomedicinal and ethnopharmaco-statistical studies of Eastern Rajasthan, India. J Ethnopharmacol. 2010; 129(1):64-86.

Diallo A, Eklu-Gadegkeku K, Mobio T, Moukha, S, Agbonon A, Aklikokou, K,. & Gbeassor M.. Protective effect of Moringa oleifera Lam. and Lannea kerstingii extracts against cadmium and ethanol-induced lipid peroxidation. J Pharmacol Toxicol. 2009; 4(4):160-166.

Arbonnier M. Arbres, arbustes et lianes des zones sèches d'Afrique de l'Ouest. 2e édn, CRAD (Centre de Coopération internationale en recherche agronomique pour le développement)-MNHN (Muséum national d'histoire naturelle); Paris. 573 p.

Ake AL, Abeye J, Guinko S, Giguet R, Bangavou X. Contribution aux étudesethnobotaniques et floristiques en République Centrafricaine. Agence de Coopération Culturelle et Technique 1st éd.Paris, 1985. 139 p.

Atawodi SE, Bulus T, Ibrahim S, Ameh DA, Nok AJ, Mamman M, Galadima M. In vitro trypanocidal effect of methanolic extract of some Nigerian savannah plants. Afr J Biotechnol. 2003; 2(9):317-321.

Diallo A, Eklu-Gadegkeku K, Agbonon A, Aklikokou K, Creppy EE, Gbeassor M. Acute and subchronic (28-day) oral toxicity studies of hydroalcoholic extract of Lannea kerstingii Engl. and K. Krause (Anacardiaceae) stem bark. J Pharmacol Toxicol. (2010); 5(7):343-349.

Marquet M and Jansen PCM. Lannea microcarpa Engl. and K. Krause. Prota 3: Dyes and Tannins/Colorants et Tanins. (2005).

Kone WM, Soro D, Dro B, Yao K, Kamanzi K. Chemical composition, antioxidant, antimicrobial and acetylcholinesterase inhibitory properties of Lannea barteri (Anacardiaceae). Aust J Basic Appl Sci. 2011; 5:1516-1523.

Amole OO, Mofomosara SH, Ekene OA. Evaluation of the antidiarrhoeal effect of Lannea welwitschii Hiern (Anacardiaceae) bark extract. Afr J Pharm Pharmacol. 2010; 4(4):151-157.

Achika JI, Ayo RG, Oyewale AO, Habila JD. Chemical investigation and antioxidant activity of fractions of Lannea humilis (Oliv.) Engl. J Turk Chem Soc. 2017; 4(2):87-96.

Garba HD, Muhammad S, Aliero AA, Muhammad HM.Antimicrobial Activity of Anogeissus Leiocarpus and Lannea Microcarpa on Some Microbes Isolated from Vegetables in Sokoto. Dev 2016; 25(17):18.

Vadivel K, Thangabalan B, Veera NK, Chetanajessygrace BD, Praveenkumar S, Babu M, Preliminary Phytochemical

Evaluation of Leaf Extracts of Lannea Corommandelica L. Int J Pharmacol Res. 2012; 2 (2):64-68.

Njinga NS, Sule MI, Pateh UU, Hassan HS, Ahmad MM, Abdullahi, ST, Bawa B. Phytochemical And Antimicrobial Activity of The Leaves of Lannea Kerstingii Engl & K. Krause (Anacadiaceae). NUJHS. 2014; 4(4):4.

Alam B, Hossain S, Habib R, Rea J, Islam A. Antioxidant and analgesic activities of Lannea coromandelica Linn. bark extract. Int. J. Pharmacol. 2012; 8(4):224-233.

Picerno P, Mencherini T, Loggia R D, Meloni M, Sanogo R, Aquino R P. An extract of Lannea microcarpa: composition, activity and evaluation of cutaneous irritation in cell cultures and reconstituted human epidermis. J Pharm Pharmacol. 2006; 58(7):981-988.

Sankara SS and Nair AGR. Angiospermae Dicotyledonae Anacardiaceae Polyphenols of Lannea coromandelica, Phytochem. 1971; 10:1939.

Islam MT and Tahara S. Dihydroflavonols from Lannea coromandelica. Phytochem. 2000; 54:901-907

Avinash KR, Jyothi MJ, Ashok K. Lannea coromandelica: The Researcher’s Tree. J Pharm Res, 20114; (3):577-579.

Islam MT, Ito T, Sakasai M, Tahara S. Zoosporicidal activity of polyflavonoid tannin identified in Lannea coromandelica stem bark against phytopathogenic oomycete Aphanomyces cochlioides. J Agric Food Chem. 2002; 50(23):6697-670.

Hassan MHM. Chemical constituents from the bark of Lannea acida rich (anacardiacea). Der Pharma Chemical, 2013; 5(5):88-96.

Sathish R, Ahmed MH, Natarajan K, Lalitha KG. Evaluation of wound healing and antimicrobial activity of Lannea coromandelica (Houtt) Merr. J Pharm. 2010; 3(6):1225-1228.

Bazongo P, Bassolé IHN, Nielsen S, Hilou A, Dicko MH, Shukla VK. Characteristics composition and oxidative stability of Lannea microcarpa seed and seed oil. Molecules2014; 19(2):2684-2693.

Achika JI, Ayo RG, Oyewale OA. Habila JD. Evaluation of Antibacterial Activity of Fractions of Lannea Humilis (Oliv.) Engl. and Synergistic Effect with Ciprofloxacin. Nig J Pharm Sci. 2017; 16(2):21-29.

Majumder R, Jami MSI, Alam MEK, Alam MB. Antidiarrheal activity of Lannea coromandelica Linn. Bark extract. American–Eurasian J Sci Res. 2013; 8:128-134.

Ouattara L, Koudou J, Zongo C, Barro N, Savadogo A, Bassole IHN, Traore AS. Antioxidant and antibacterial activities of three species of Lannea from Burkina Faso. J Appl Sci. 2011; 11:157-162.

Srinivasa VR, John W, Kuntal D. Hepatoprotective and antioxidant activity of Lannea coromandelica Linn. on thioacetamide induced hepatotoxicity in rats. Int Lett Nat Sci. 2014; 3:33-40.

Lamien-Meda A, Lamien CE, Compaoré MM, Meda RN, Kiendrebeogo M, Zeba B, Millogo JF, Nacoulma OG. Polyphenol content and antioxidant activity of fourteen wild edible fruits from Burkina Faso. Molecules 2008; 13(3):581-594.

Weerapreeyaku N, Junhom C, Barusrux S, Thitimetharoch T. Induction of apoptosis in human hepatocellular carcinoma cells by extracts of Lannea coromandelica (Houtt.) 2016; 11(19):45-48.

Singh S and Singh GB. Hypotensive activity of Lannea coromandelica bark extract. Phytother Res. 1996; 10(5):429-430.

Kamaluddeen G. Anticonvulsant effects of ethanol stem bark extract of Lannea barteri (Anacardiaceae) in mice and chicks. Clin Exp Pharmacol. 2016; 6:2

Downloads

Published

2018-10-01

How to Cite

I. Achika , J. (2018). A Review of the Phytochemistry and Pharmacology of Lannea species: doi.org/10.26538/tjnpr/v2i10.1 . Tropical Journal of Natural Product Research (TJNPR), 2(10), 442–446. Retrieved from https://tjnpr.org/index.php/home/article/view/844