A Mini Systematic Review: Eucheuma cottonii, a Red Algae, as a Radiosensitizer?

doi.org/10.26538/tjnpr/v5i1.2

Authors

  • Tisa P. Putri Department of Radiation Oncology, Dr. Cipto Mangunkusumo National General Hospital, Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia
  • Ida A.T.K. Dewi Department of Radiation Oncology, Dr. Cipto Mangunkusumo National General Hospital, Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia
  • Tiara B.M. Permata Department of Radiation Oncology, Dr. Cipto Mangunkusumo National General Hospital, Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia
  • Endang Nuryadi Department of Radiation Oncology, Dr. Cipto Mangunkusumo National General Hospital, Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia
  • Henry Kodrat Department of Radiation Oncology, Dr. Cipto Mangunkusumo National General Hospital, Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia
  • Heri Wibowo Diagnostic and Research Center, Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia
  • Melva Louisa Department of Pharmacology and Therapeutic, Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia
  • Soehartati A. Gondhowiardjo Department of Radiation Oncology, Dr. Cipto Mangunkusumo National General Hospital, Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia

Keywords:

Eucheuma cottonii, Anti-tumour, Radiosensitizer, Immunomodulator

Abstract

Radiosensitizers assist radiotherapy in providing greater tumor inactivation. Currently there is a search for natural radiosensitizer components which are expected to provide lesser side effects than chemical radiosensitizers. Eucheuma cottonii is a plant with antioxidant and anti-tumor effects. This review aims to search for the potential use of Eucheuma cottonii as a radiosensitizer. This is a mixed review study, where the main component is a systematic review and then followed by a narrative review. This review suggests that Eucheuma cottonii has the potential to become a radiosensitizer, by interfering with the cell cycle control mechanisms and reactivation of p53. Further research is needed to explore the synergistic effect of the combined use of radiotherapy and Eucheuma cottonii

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Published

2021-01-01

How to Cite

Putri, T. P., Dewi, I. A., Permata, T. B., Nuryadi, E., Kodrat, H., Wibowo, H., … Gondhowiardjo, S. A. (2021). A Mini Systematic Review: Eucheuma cottonii, a Red Algae, as a Radiosensitizer? doi.org/10.26538/tjnpr/v5i1.2. Tropical Journal of Natural Product Research (TJNPR), 5(1), 7–15. Retrieved from https://tjnpr.org/index.php/home/article/view/813

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