Phytochemical Content, Antioxidant and Antibacterial Activities of Three Red Macroalgae from Algerian West Coast
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Abstract
Over the last few decades, isolations and chemical characterizations of secondary metabolites with proven biological activities have been of interest for numerous research groups across the world. Reports on phenolic potentials of marine algae are still scarce. The aim of this study deals with the evaluation of the in vitro antioxidant and antibacterial properties of methanolic extracts from three red algae species (Asparagopsis taxiformis, Hypnea musciformis, and Corallina elongata) collected from Algerian west coast (Oran). Moreover, the extracts were investigated for their polyphenol, flavonoid and tannin contents. Extracts were tested in vitro for their antibacterial activity against several pathogenic bacteria including seven ATCC reference strains and five clinical multidrug-resistant bacteria. The results showed that the C. elongata exhibited highest phenolic content (18.69± 0.016 GAE/g) and higher condensed tannins content (06.56 ± 0.015mg CE/g extract). Total flavonoids content was highest in methanolic extract of A. taxiformis (8.86 ± 0.006 mg QE/g) extract. Among three algae tested, the methanol extract of C. elongata exhibited the strongest DPPH scavenging capacity with IC50 of 0.11 mg/mL. Each extracts displayed different degrees of antibacterial activity against at least four tested antibacterial strains. Salmonella typhimurium ATCC 13311, Escherichia coli ATCC 25922, Bacillus cereus ATCC 11778 and Staphylococcus aureus ATCC 25923 were found to be sensitive to the three extracts. Results of present study confirmed the potential usefulness of marine algae in the pharmaceutical and biotechnological industries.
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