Anopheles gambiae Control and Antibacterial Activities of Silver, Gold, and their Alloy Nanoparticles Synthesized Using Pleurotus ostreatus
DOI:
https://doi.org/10.26538/tjnpr/v9i10.62Keywords:
Thrombolytic effect, Antibacterial activity, Mosquito control, Pleurotus ostreatus, NanoparticlesAbstract
Mosquitoes, the primary malaria vectors in Nigeria, have developed increasing resistance to synthetic insecticides, necessitating the search for eco-friendly alternatives. This study investigates the insecticidal and biomedical properties of silver nanoparticles (AgNPs), gold nanoparticles (AuNPs), and silver-gold alloy nanoparticles (Ag-AuNPs) synthesized via a green method using Pleurotus ostreatus extracts. Nanoparticles were characterized using UV-visible spectroscopy and Fourier-transform infrared spectroscopy (FTIR). Their larvicidal and pupicidal efficacy was tested at 1–30 µg/mL concentrations over 12 and 24 hours, while adult mosquitoes were exposed to nanoparticle-infused coil fumes. Additionally, antibacterial activity against eight clinical bacterial isolates was evaluated. UV-visible spectroscopy showed maximum absorbance at 430, 550, and 540 nm for AgNPs, AuNPs, and Ag-AuNPs, respectively, while FTIR analysis confirmed functional group interactions at 3778, 3262, and 3037 cm¹. Mortality increased with concentration and exposure time, with a maximum effect at 170 µg/mL for adult mosquitoes. Antibacterial tests revealed inhibition zones of 5–12 mm at 10–50 µg/mL concentrations. These findings highlight the potential of Pleurotus ostreatus-derived nanoparticles as effective biopesticides with promising antibacterial applications.
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