Parquetina nigrescens Species: A Concise Review of Phytochemistry and Pharmacology
doi.org/10.26538/tjnpr/v6i4.1
Keywords:
Parquetina nigrescens, Bioactive Component, Pharmacologic Activity, PhytochemicalAbstract
Parquetina nigrescens species is a member of the Periploceaceae family, found majorly across countries in Africa. It has myriads of folkloric uses till date in this region. It is sometimes used in combination with other plants traditionally to treat several ailments such s inflammation, insanity, diarrhoea, skin infections, gonorrhoea, menstruation aberrations, helminthic infections, sexual disorders and some other complicated disorders. Based on our search, there is no review article to date on the authenticated biological activities of P. nigrescens, despite numerous researches. This review aims at presenting a novel summary of established pharmacological properties and mechanisms of action of Parquetina nigrescens. Several bioactive components such as flavonoids, saponins, alkaloids, tannins, free and bound anthraquinones, phlobatinins, terpenoid, cardenolides, triterpenes etc. have been derived from chemical analysis of Parquetina nigrescens, these play important roles in the detected pharmacological activities of the plant such as anti-diabetic, anti- cancer, anti-inflammatory, anti-oxidant, anti-diarrhoea, anti-sickling, anti-neurotoxic, anti-apoptotic anti-microbial, anti-nociceptive, antiulcer, aphrodisiac and anti-neurodegenerative properties as reported by several researchers. Thus, the plant has a promising outlook for drug discovery and development.
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