Sea Lettuce (Ulva lactuca) as a Source of Dietary Antioxidant doi.org/10.26538/tjnpr/v5i4.1

Main Article Content

Luh P. R. Sundari
Putu A. W. Wijaya

Abstract

Sea lettuce (Ulva lactuca) is a local food with high antioxidant activity. It exists as a green algae and lives in shallow waters, especially on rocky beaches. Several studies have demonstrated Ulva's bioactive compounds and their antioxidant effect on several health parameters. The plant is also known to contain vitamin C, total phenolics, and Vitamin E (alpha-tocopherol), hence, it has anti-peroxidation and anti-hyperlipidemic effects. In addition, Ulva lactuca also has anti-inflammatory effect due to its ability to inhibit free radicals. This review will discuss how the active ingredients contained in Ulva lactuca act in the body that they can be a potential dietary source of antioxidants.

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How to Cite
Sundari, L. P. R., & Wijaya, P. A. W. (2021). Sea Lettuce (Ulva lactuca) as a Source of Dietary Antioxidant: doi.org/10.26538/tjnpr/v5i4.1. Tropical Journal of Natural Product Research (TJNPR), 5(4), 603-608. https://tjnpr.org/index.php/home/article/view/661
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How to Cite

Sundari, L. P. R., & Wijaya, P. A. W. (2021). Sea Lettuce (Ulva lactuca) as a Source of Dietary Antioxidant: doi.org/10.26538/tjnpr/v5i4.1. Tropical Journal of Natural Product Research (TJNPR), 5(4), 603-608. https://tjnpr.org/index.php/home/article/view/661

References

Dewi NNDT, Wrasiati LP, Putra GPG. Pengaruh Konsentrasi Pelarut etanol dan Suhu Maserasi terhadap

Rendemen dan Kadar Klorofil Produk Enkapsulasi Ekstrak Selada Laut (Ulva lactuca L.). JRMA. 2016; 4(3):59-70.

Sathivel A, Raghavendran HR, Srinivasan P, Devaki T. Anti- peroxidative and Anti-hyperlipidemic Nature of Ulva lactuca crude polysaccharide on D-Galactosamine induced hepatitis in rats. Food Chem Toxicol. 2008; 46:3262-3267.

Hassan S, El-Twab SA, Hetta M, Mahmoud B. Improvement of Lipid Profile and Antioxidant of Hypercholesterolemic Albino Rats by Polysaccharides Extracted from Green Alga Ulva lactuca Linnaeus. Saudi J Biol Sci. 2011; 18:333-340.

Sathivel A, Balavinayagamani, Hanumantha Rao BR, Devaki T. Sulfated Polysaccharide isolated from Ulva

lactuca attenuates D-galactosamine induced DNA fragmentation and Necrosis during Liver Damage in Rats.

Pharm Biol. 2014; 52(4):498-505.

Yunita D, Wrasiati LP, Suhendra L. Karakteristik Senyawa Bioaktif Ekstrak Selada Laut (Ulva lactuca L.) pada

Konsentrasi Pelarut Etanol dan Lama Ekstraksi. JRMA. 2018; 6(3):189-195.

Kim DY, Kim J, Ham HJ, Choue R. Effects of d-α-tocopherol supplements on lipid metabolism in a high-fat

diet-fed animal model. Nutr Res Pract. 2013; 7(6):481-487.

Rafiei H, Omidian K, Bandy B. Dietary Polyphenols Protect Against Oleic Acid-Induced Steatosis in an In VitroModel of NAFLD by Modulating Lipid Metabolism and Improving Mitochondrial Function. Nutr. 2019; 11(3):541.

Chen G, Ni Y, Nagata N, Xu L, Ota T. Micronutrient Antioxidants and Nonalcoholic Fatty Liver Disease. Int J

Mol Sci. 2016; 17(9):1379.

Yu-Qing T, Mahmood K, Scehzadi R, Asharf MF. Ulva lactuca and Its Polysaccharides: Food and Biochemical

Aspects. J Biol Agric Health. 2016; 6(1):140-151.

Perumpail BJ, Li AA, John N, Sallam S, Shah ND, Kwong W, Cholankeril G, Kim D, Ahmed A. The Role of Vitamin E in the Treatment of NAFLD. Dis. 2018; 6(4):86.

Widyaningsih W, Sativa R, Primardiana I. Efek Antioksidan Ekstrak Etanol Ganggang Hijau (Ulva lactuca

L.) terhadap Kadar Malondialdehid (MDA) dan Aktivitas Enzim Superoksida Dismutase (SOD) Hepar Tikus yang Diinduksi CCl4. Media Farmasi. 2015; 12(2):163-175.

Kammoun I, Ben-Salah H, Ben-Saad H, Cherif B, Droguet M, Magné C, Kallel C, Boudawara O, Hakim A, Gharsallah N, Ben Amara I. Hypolipidemic and cardioprotective effects of Ulva lactuca ethanolic extract in

hypercholesterolemic mice. Arch Physiol Biochem. 2018;124(4):313-325

Tariq A, Athar M, Ara J, Sultana V, Ehteshamul-Haque S, Ahmad M. Biochemical Evaluation of Antioxidant Activity in Extracts and Polysaccharide Fractions of Seaweeds. Global J Environ Sci Manage. 2015; 1:47-62.

Pizzino G, Irrera N, Cucinotta M, Pallio G, Mannino F, Arcoraci V, Squadrito F, Altavilla D, Bitto A. Oxidative

Stress: Harms and Benefits for Human Health. Oxid Med Cell Longev. 2017; 2017:8416763.

Dominguez H and Loret EP. Ulva lactuca, A Source of Troubles and Potential Riches. Mar Drugs. 2019;

(357):1-20.

Yaich H, Garna H, Bichir B, Besbes S, Paquot M, Richel A, Blecker C, Attia H. Chemical Composition and Functional Properties of Dietary Fiber Extracted by Englyst and Porsky Method from the Alga Ulva lactuca Collected in Tunisia. Algal Res. 2015; 9:65-73.

Elmegeed DFA, Ghareeb DA, Elsayed M, El-Saadani M. Phytochemical Constituents and Bioscreening Activities of Green Algae (Ulva lactuca). Int J Agric Pol Res. 2014; 2 (11):372-378.

Whankatte VR and Ambhore JS. Research Article: Phytochemical Screening and Antioxidant Activity of Ulva lactuca. Int J Curr Res. 2016; 8(9):38265-38269.

Mahmud I, Pertiwi R, Azis NR, Reviana DN. Pemanfaatan Potensi ganggang Hijau (Ulva lactuca) sebagai Antioksidan Alami pada Pencegahan Infark Miokard Akut. EProceeding PIMNAS PKM-P Ditjen Dikti mdikbud RI. [Online]PKM-P 2014. Available at: http://artikel.dikti.go.id/index.php/PKMP/issue/view/35downloaded on: 21st March 2018.

Ktari, L. Pharmacological Potential of Ulva Species: A Valuable Resource. J Anal Pharm Res. 2017; 6(1):00165.

Rasyid, A. Evaluation of Nutritional Composition of The Dried Seaweed Ulva lactuca from Pameungpeuk Waters, Indonesia. Trop Life Sci Res. 2017; 28:119-125.

Prasedya E, Martyasari NW, Apriani R, Mayshara S, Fanani R, Sunarpi H. Antioxidant activity of Ulva lactuca L. from different coastal locations of Lombok Island, Indonesia. AIP Conf Proc. 2019; 2199:020003.

Kokabi M, Yousefzadi M, Ahmadi A, Feghhi-Amin M, Keshavarz and Mousa. Antioxidant Activity of Extracts of Selected Algae from the Persian Gulf, Iran. Ulum Va Tiknuluzhii Khaliji Fars. 2013; 4:45-50.

Alagan V, Rajesh NV, Rajesh KD. Bioactive Chemical Constituent Analysis, in vitro Antioxidant and

Antimicrobial Activity of Whole Plant Methanol Extracts of Ulva lactuca Linn. Br J Pharm Res. 2017; 15:1-14.

Zubia M, Robledo D, Freile-Pelegrin Y. Antioxidant activities in tropical marine. Macroalgae from the Yucatan Peninsula, Mexico. J Appl Phycol. 2007; 19(5):449-458.

Ortiz J, Romero N, Robert P, Araya J, Lopez-Hernandez J, Bozzo C, Navarrete E, Osorio A, Ríos A. Dietary fiber, amino acid, fatty acid and tocopherol contents of the edible seaweeds Ulva lactuca and Durvillaea antarctica. Food Chem. 2006; 99.

Wrasiati LP, Yunita NLGD, Suhendra L, Wijaya IMAS. Optimization of material concentration and extraction time on yield and α-tocopherol content of sea lettuce (Ulva lactuca L.) IOP Conf Ser Earth Environ Sci. 2019; 230: 012054.

Sundari LPR, Adiputra N, Dinata IMK. Supplementation of Vitamin E 400 IU Decreases Malondialdehyde Level of Obese Women Staff at School of Medicine Udayana University. Asian J Pharm Clin Res. 2017; 10(9):61-63.

Nan YM, Wu WJ, Fu N, Liang BL, Wang RQ, Li LX, Zhao SX, Zhao JM, Yu J. Antioxidants vitamin E and 1-

aminobenzotriazole prevent experimental non-alcoholic steatohepatitis in mice. Scand J Gastroenterol. 2009;

(9):1121-1131.

Rimbach G, Moehring J, Huebbe P, Lodge JK. Gene-regulatory activity of alpha-tocopherol. Molecules. 2010; 15(3):1746-1761.

Ipsen DH, Tveden-Nyborg P, Lykkesfeldt J. Does Vitamin C Deficiency Promote Fatty Liver Disease Development? Nutr. 2014; 6:5473-5499.

Wei J, Lei GH, Fu L, Zeng C, Yang T, Peng SF. Association between Dietary Vitamin C Intake and NonAlcoholic Fatty Liver Disease: A Cross-Sectional Study among Middle-Aged and Older Adults. PloS One. 2016; 11(1):e0147985.

Foster T, Budoff MJ, Saab S, Ahmadi N, Gordon C, Guerci AD. Atorvastatin and antioxidants for the treatment of nonalcoholic fatty liver disease: the St Francis Heart Study randomized clinical trial. Am J Gastroenterol. 2011; 106(1):71-77.

Khairy HM and El-Sheikh MA. Antioxidant activity and mineral composition of three Mediterranean common seaweeds from Abu-Qir Bay, Egypt. Saudi J Biol Sci. 2015; 22(5): 623-630.

El baky H, El-Baz F, El baroty G. Evaluation of Marine Alga Ulva lactuca L. as A Source of Natural Preservative Ingredient. Am-Euras J Agric Environ Sci. 2008; 3:434-444.

Zaatout H, Ghareeb D, Abd-Elgwad A, Ismael A. Phytochemical, antioxidant, and anti-inflammatory

screening of the Egyptian Ulva lactuca methanolic extract. Rec Pharm Biomed Sci. 2019; 33-38.

Sanz-Pintos N, Pérez-Jiménez J, Buschmann AH, VergaraSalinas JR, Pérez-Correa, JR, Saura-Calixto F. Macromolecular antioxidants and dietary fiber in edible seaweeds. J Food Sci. 2017; 82:289-295.

Fomenko SE, Kushnerova NF, Sprygin VG, Drugova ES, Lesnikova LN, Merzlyakov, V.Yu, Momot TV. Lipid

Composition, Content of Polyphenols, and Antiradical Activity in Some Representatives of Marine Algae. Russ J Plant Physiol. 2019; 66:942-949.

Ravindran NT and Sadiq M. Pharmacological Activity of Ulva Lactuca Polyphenols Fraction: Hepatoprotective and Antioxidant Activities Against Paracetamol-Induced Liver Damage In Rats. Asian J Pharm Clin Res. 2019; 12:55-58.

Yang CQ, Shu L, Wang S, Wang JJ, Zhou Y, Xuan YJ, Wang SF. Dietary Patterns Modulate the Risk of NonAlcoholic Fatty Liver Disease in Chinese Adults. Ntr. 2015; 7(6):4778-4791.