A New Biflavonoid Glycoside from the Leaves of Ziziphus mucronata Willd. (Rhamnaceae) doi.org/10.26538/tjnpr/v2i4.3

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Published: Apr 1, 2018
Keywords:
Ziziphus mucronata,, Isolation,, Structure elucidation,, bis (quercetin 3-O- β-D-glucopyranoside).

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Musa S. Abdullahi
Department of Pharmaceutical and Medicinal Chemistry, Ahmadu Bello University, Zaria, Nigeria.
Muhammad A. Musa
Department of Pharmaceutical and Medicinal Chemistry, Ahmadu Bello University, Zaria, Nigeria.
Isma’il M. Abdullahi
Department of Pharmaceutical and Medicinal Chemistry, Usmanu Danfodiyo University, Sokoto, Nigeria
Mohammed Y. Sani
Department of Pharmaceutical and Medicinal Chemistry, Ahmadu Bello University, Zaria, Nigeria.
Sadiya H. Hassan
Department of Pharmaceutical and Medicinal Chemistry, Ahmadu Bello University, Zaria, Nigeria.
Jamilu Ya’u
Department of Pharmacology and Therapeutics, Ahmadu Bello University, Zaria, Nigeria.

Abstract

A new compound was isolated from the n-butanol fraction of the crude methanol extract of the leaves of Ziziphus mucronata, a plant that is widely used in ethnomedicine to treat inflammation, diarrhoea, tumour, cough, sores, asthma, measles, fever, infections and urinary problems, amongst numerous indications. The isolation of the compound was carried out by a combination of silica gel column and sephadex gel filtration chromatography and the structure was elucidated with the help of UV, IR, and 1D, 2D -
1H and 13C NMR spectroscopic analysis. The compound, a glycoside biflavonoid, was established as bis (quercetin 3-O-β-D-glucopyranoside). The compound might be responsible for some of the observed biological activities of the plant Ziziphus mucronata.

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How to Cite
S. Abdullahi, M., A. Musa, M., M. Abdullahi, I., Y. Sani, M., H. Hassan, S., & Ya’u, J. (2018). A New Biflavonoid Glycoside from the Leaves of Ziziphus mucronata Willd. (Rhamnaceae): doi.org/10.26538/tjnpr/v2i4.3 . Tropical Journal of Natural Product Research (TJNPR), 2(4), 167-170. https://tjnpr.org/index.php/home/article/view/540
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Vol. 2 No. 4 (2018): Tropical Journal of Natural Product Research
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Articles
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This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

How to Cite

S. Abdullahi, M., A. Musa, M., M. Abdullahi, I., Y. Sani, M., H. Hassan, S., & Ya’u, J. (2018). A New Biflavonoid Glycoside from the Leaves of Ziziphus mucronata Willd. (Rhamnaceae): doi.org/10.26538/tjnpr/v2i4.3 . Tropical Journal of Natural Product Research (TJNPR), 2(4), 167-170. https://tjnpr.org/index.php/home/article/view/540

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