Phyllencit Mixture, a Combination of Medicinal Herbs, as an Antitussive Agent for Acute Cough Treatment: A Pilot Pre-Post Clinical Study doi.org/10.26538/tjnpr/v5i8.9

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Julalak Chokpaisarn
Kotchakorn Moosigapong
Teerawat Sudkhaw
Somporn Chanwanitsakul
Suwanee  Promsombat
Kullaya Pibun
Suchada Sakwijan
Nichakan Sukcharung

Abstract

PhyllenCit, a herbal anti-cough mixture, has been traditionally used in Traditional Thai Medicine hospital, Prince of Songkla University, for the treatment of oral diseases, as well as cough. However, the efficacy of the recipe has not been validated. Therefore, this current study aimed to clinically prove the efficacy of the PhyllenCit mixture in suppressing cough and improving quality of life (QOL) in patients with acute cough. PhyllenCit mixture used for this study was prepared by a traditional Thai doctor at a Traditional Thai Medicine hospital. This study was a single-centre, open blind, pre-post clinical trial. Patients were recruited for the experiment according to the inclusion and exclusion criteria. The assessment of cough level, cough severity index, and a score of QOL was performed before starting the treatment. Patients with acute cough were advised to take the mixture (5 mL) orally for three days. At the end of the study, all the parameters were assessed. The frequency of cough and any adverse effects observed throughout the treatment period (day 1 to day 3) were also recorded by patients. The study revealed that after three days of the intervention, levels of cough symptoms and total severity of cough were significantly extenuated (p<0.05), which was associated with changes in throat characteristics and tonsil size. Similarly, significant improvement of QOL in the patientswas observed with no adverse effects. This  work scientifically proved that PhyllenCit mixture could be used as an antitussive agent in cases of acute cough. 

Article Details

How to Cite
Chokpaisarn, J., Moosigapong, K., Sudkhaw, T., Chanwanitsakul, S., Promsombat, S., Pibun, K., … Sukcharung, N. (2021). Phyllencit Mixture, a Combination of Medicinal Herbs, as an Antitussive Agent for Acute Cough Treatment: A Pilot Pre-Post Clinical Study: doi.org/10.26538/tjnpr/v5i8.9. Tropical Journal of Natural Product Research (TJNPR), 5(8), 1375–1381. Retrieved from https://tjnpr.org/index.php/home/article/view/442
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Author Biographies

Julalak Chokpaisarn, Traditional Thai Medicine Hospital, Faculty of Traditional Thai Medicine, Prince of Songkla University, Hat Yai, Songkhla, 90110, Thailand

Traditional Thai Medical Research and Innovation Center, Faculty of Traditional Thai Medicine, Prince of Songkla University, Hat Yai, Songkhla 90110, Thailand

Kotchakorn Moosigapong, Traditional Thai Medicine Hospital, Faculty of Traditional Thai Medicine, Prince of Songkla University, Hat Yai, Songkhla, 90110, Thailand

Traditional Thai Medical Research and Innovation Center, Faculty of Traditional Thai Medicine, Prince of Songkla University, Hat Yai, Songkhla 90110, Thailand

Teerawat Sudkhaw, Traditional Thai Medicine Hospital, Faculty of Traditional Thai Medicine, Prince of Songkla University, Hat Yai, Songkhla, 90110, Thailand

Traditional Thai Medical Research and Innovation Center, Faculty of Traditional Thai Medicine, Prince of Songkla University, Hat Yai, Songkhla 90110, Thailand

Somporn Chanwanitsakul, Traditional Thai Medicine Hospital, Faculty of Traditional Thai Medicine, Prince of Songkla University, Hat Yai, Songkhla, 90110, Thailand

Traditional Thai Medical Research and Innovation Center, Faculty of Traditional Thai Medicine, Prince of Songkla University, Hat Yai, Songkhla 90110, Thailand

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