Topical Antimicrobial Microparticle-Based Polymeric Materials for Burn Wound Infection
doi.org/10.26538/tjnpr/v5i10.1
Keywords:
Burn, Bacterial infection, Human skin, Microparticles, Topical, WoundAbstract
Microparticles are one of the delivery systems which protect drugs from the harsh environments and also can stabilize drugs or eliminate discrepancies. The aim of this study was to discuss topical microparticle delivery system which contains natural oils for burn wounds and also to classify burns and wound healing process. This scoping review consists of 50 publications from periods between 2016 and 2020 which resulted from the extraction of 63 publications from search engines using various keywords. Data of publications that met the inclusion and exclusion criteria were extracted manually. Most publications presented on burn wound treatment used microparticles containing synthetic drugs and natural oils. The review also pointed at a wide variety of topical product dosage forms related to formulations that range in consistency from liquid to semi-solid preparations, but the most popular product is the semi-solid preparations. The use of natural oils in topical microparticles using natural or synthetic polymers provides more advantages and is recommended for drug or cosmetic development specifically in wound care.
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