Effect of Thyme Essential Oil on Serum Lipid Profile and Renal Function in Meleagris gallopavo http://www.doi.org/10.26538/tjnpr/v8i1.7
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Abstract
Currently, aromatic plants and their extracts have become an interesting area of research as a means of improving animal health and productivity. This study aimed to evaluate the effect of thyme essential oil (thymol) on key metabolic functions in turkeys. Twenty (20) wild female turkeys (Meleagris gallopavo) aged 16 days were used for the study. The animals were divided into two groups of 10 turkeys each. Group 1 (control) were fed with the normal diet, while group 2 (treatment) had thyme essential oil added to their diet, and administered for 30 days. The body weights of the animals were monitored throughout the treatment duration. After the treatment period, renal function parameters and serum lipids were evaluated. The average weight of the animals in the treatment group was 1420 g, which was twice as high as that of the control (690 g). Supplementation of poultry diet with thyme essential oil reduced serum levels of total cholesterol (2.76 ± 0.08 g/L), triglycerides (1.90 ± 0.52 g/L), urea (3.91 ± 0.95 g/L), and creatinine (1.68 ± 0.61 g/L), compared to the control group which had higher serum total cholesterol (5.15 ± 0.46 g/L), triglycerides (4.93 ± 0.95 g/L), urea (8.75 ± 2.25 g/L), and creatinine (6.45 ± 0.56 g/L). The present study highlighted the beneficial effect of thyme essential oil by improving serum biochemical parameters in turkeys. Therefore, the use of thyme essential oil in poultry feed should be encouraged in order to improve poultry health and productivity.
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References
Namdeo S, Baghel R, Nayak S, Khar A, Pal RP, Chaurasiya A, Thakur S, Reddy B. Essential oils: a potential substitute to antibiotics growth promoter in broiler diet. J Entomol Zool Stud. 2020; 8:1643–1649.
Klimiuk K, Sembratowicz I, Czech A. Effect of thyme (Thymus vulgaris L.) used in extruded flaxseed diets on the antioxidant and lipid profile of blood and tissues of
fattening pigs. Novel Antioxid Anim Nutr. 2023; 12(5) :1045.
Mehmet B and Ahmet ET. Feed Additives: Plants and Aromatic Herbs in Animal Nutrition and Health. 2020: 205-226 p.
Puvaca N, Tufarelli V, Giannenas I. Essential oils in broiler production, immunity, and meat quality: A review of Thymus vulgaris, Origanum vulgare, and Rosmarinus officinalis. Agric. 2022; 12 :874.
Brenes A and Roura E. Essential oils in poultry nutrition: main effects and modes of action. Anim Feed Sci Technol. 2010; 158(1-2):1–14.
Yaqoob MU, Wang G, Wang M. An updated review on probiotics as an alternative of antibiotics in poultry - A review. Anim Biosci. 2022; 35(8):11091120.
Rodríguez-Yoldi MJ. Anti-Inflammatory and Antioxidant Properties of Plant Extracts. Antioxid. 2021; 10(6):921.
Falodun A, Siraj R, Choudhary MI. GC-MS Insecticidal Leaf essential oil of P. staudtii Hutch and Dalz (Icacinaceae). Trop J Pharm Res. 2009; 82:139-143.
Okolie NP, Falodun A, Oluseyi D. Evaluation of the antioxidant activity of root extract of pepper fruit (Dennetia tripetala), and its potential for the inhibition of Lipid peroxidation. Afr J Trad Compl Altern Med. 2014; 11(3):221-227.
Marchese A, Orhan IE, Daglia M, Barbieri R, Di Lorenzo A, Nabavi SF, Gortzi O, Izadi M, Nabavi SM. Antibacterial and antifungal activities of thymol. A brief review of the literature. Food Chem. 2016; 210:402414.
Dahmani F, El-Mouhdi K, Laamiri FZ, Ibriz M. Assessment of the Effect of Thyme Essential Oil on Biochemical Parameters in Endurance Horses. Trop J Nat Prod Res. 2023; 7(6):3130-3135.
Damiescu R, Lee DYW, Efferth T. Can Essential Oils Provide an Alternative Adjuvant Therapy for COVID-19 Infections and Pain Management at the Same Time. Pharm (Bassel). 2022; 15(11):1387.
Tanghort M, Chefchaou H, Mzabi A, Moussa H, Chami N, Chami F, Remmal A. Oocysticidal Effect of Essential Oils (EOs) and their Major Components on Cryptosporidium baileyi and Cryptosporidium galli. Int J Poult Sci. 2019; 18:475–482.
Hriouech S, Akhmouch AA, Mzabi A, Chefchaou H, Tanghort M, Oumokhtar B, Chami N, Remmal A. The Antistaphylococcal Activity of Amoxicillin/Clavulanic Acid, Gentamicin, and 1,8-Cineole Alone or in Combination and Their Efficacy through a Rabbit Model of Methicillin-Resistant Staphylococcus aureus Osteomyelitis. Evid-Based Compl Altern Med. 2020; 2020:e4271017.
Pan D and Yu Z. Intestinal microbiome of poultry and its interaction with host and diet. Gut Microbes. 2014; 5:108–119.
Vlaicu PA, Saracila M, Panaite TD, Tabuc C, Bobe E, Criste RD. Effect of the dietary grape seeds and rosehip oils given to broilers (14−42 days) reared at 32°C on broiler performance, relative weight of carcass cuts and internal organs and balance of gut microflora. Archiv Zootech. 2017; 20:77–88.
Alagawany M, Madkour M, El-Saadony MT, Reda FM. Paenibacillus polymyxa (LM31) as a new feed additive: antioxidant and antimicrobial activity and its effects on growth, blood biochemistry, and intestinal bacterial populations of growing Japanese quail. Anim Feed Sci Technol. 2021; 276:114920.
Mousavi A, Mahdavi AH, Riasi A, Soltani-Ghombavani M. Efficacy of essential oil combination on performance, ileal bacterial count, intestinal histology and immunocompetence of laying hens fed with other lipid sources. J Anim Physiol Anim Nutr (Berlin). 2018 ; 102:1245-1256.
Alagawany M, Madkour M, El-Saadony MT, Reda FM. Paenibacillus polymyxa (LM31) as a new feed additive: antioxidant and antimicrobial activity and its effects on growth, blood biochemistry, and intestinal bacterial populations of growing Japanese quail. Anim Feed Sci Technol. 2021; 276:114920.
Supchukun K, Yata T, Israsena Na, Ayudhya P, Angkanaporn K. Key success factors for the development of innovative antibiotic replacement products to accelerate broiler growth. Sustain. 2022; 14 :10459.
El-Mouhdi K, Fekhaoui M, Rzeq M, Ennassih Y, Chahlaoui A. Knowledge and behaviour of individuals towards sandflies’ vectors of leishmaniasis in Morocco]. East Mediterr Health J. 2021; 27:911–917.
Entomological Exploration of Sand Flies in Human Communities Affected by Cutaneous and Visceral Leishmaniasis in El Hajeb Province, Morocco. T S W J. 2023: e4628625. Doi : 10.1155/2023/4628625
El-Mouhdi1 K, Dahmani F, Lhilali I, Zouine N, Chahlaoui A, Fekhaoui M, Boussaa S. Perception and use of Medicinal Plants and Chemical Products in the Traditional Treatment of Cutaneous Leishmaniasis in Morocco. Trop J Nat Prod Res. 2023; 7(5):29462951.
Tkachenko K and Varfolomeeva E. Prospects for the Use of Essential Oils as Repellants and/or Insecticides. Trop J Nat Prod Res. 2022; 6(6):831-835.
Jeddi M, Fikri-Benbrahim K, El Hachlafi K, Benkhaira, N, Aboussemdai A, Ouaritini ZB. Chemical Composition of Thymus vulgaris, Origanum compactum and Vetiveria zizanoides Essential oils and their Antibacterial and Antioxidant Activities. Trop J Nat Prod Res. 2023; 7(1):2244-2250.
El-Mouhdi K, Boussaa S, Chahlaoui A and Fekhaoui M. « Prevalence and risk factors of canine leishmaniasis in Morocco: a systematic review and meta-analysis,” J Parasit Dis. 2022. 46, 967–987. Doi:10.1007/s12639-022-01521-2.
Mallak N. Turkey meat production. Vet Area. 2000; N°27.
Hriouech S, Akhmouch AA, Tanghort M, Chefchaou H, Mezabi A, Chami N, Remmal A. In Vitro and In Vivo Comparison of Changes in Antibiotics Susceptibility of E. coli and Chicken’s Intestinal Flora after Exposure to Amoxicillin or Thymol. Vet Med Int. 2020; 2020:e8824008.
Guder WG and Hoffmann GE. Multicentre evaluation of an enzymatic method for creatinine determination using a sensitive colour reagent. J Clin Chem Clin Biochem. 1986; 24:889-902.
Khaksar V, Krimpen MV, Hashemipour H, Pilevar M. Effects of thyme essential oil on performance, some blood parameters and ileal microflora of Japanese quail. J Poult Sci. 2012; 49(2):106-110.
Popovic S, Puvača N, Kostadinović L, Džinić N, Bošnjak J, Vasiljević M, Djuragic O. Effects of dietary essential oils on productive performance, blood lipid profile, enzyme activity and immunological response of broiler chickens. Eur Poult Sci. 2016; 80:1-12.
Mia S, Kabir R, Ahmad N, Hasan M, Enyetornye B, Ghana Dei HK, Herbert K Dei, Asare GA, Anning GK, Hossain M, Nooruzzaman M. Studies on the haemato-biochemical changes in growing broilers after being fed on Icacina oliviformis (false yam) tuber meal. J Anim Sci Vet Med. 2022; 7:52–58.
Amouei H, Ferronato G, Qotbi AAA, Bouyeh M, Dunne PG, Prandini A, Seidavi A. Effect of Essential Oil of Thyme (Thymus vulgaris L.) or Increasing Levels of a Commercial Prebiotic (TechnoMOS®) on Growth Performance and Carcass Characteristics of Male Broilers. Anim (Basel). 2021; 11(11):3330.
Kaya A and Turgut L. Effects of sage (Salvia officinalis), thyme (Thymbra spicata), mentha (Mentha piperita) extracts and vitamin E supplementation at different levels into diets of hens on performance, egg quality, and yolk TBARS values. J Agric Fac Atatürk Univ. 2012; 43:49-58.35.Gerzılov V, Nıkolov A, Petrov P, Bozakova N, Penchev
G, Bochukov A. Effect of a dietary herbal mixture supplement on the growth performance, egg production and health status in chickens. J Central Eur Agric. 2015; 16(2):10-27.
Belenli D, Udum D, Şule Cengiz S, Polat U. Influence of various volatile oils as a dietary supplement on biochemical and performance parameters in broilers. J Biol Environ Sci. 2015; 9:47-55.
Behnamifar A, Rahimi S, Karimi Torshizi MA, Hasanpour S, Mohammadzade Z. Effect of thyme, garlic and caraway herbal extracts on blood parameters, productivity, egg quality, hatchability, and intestinal bacterial population of laying Japanese quail. Iran J Vet Med. 2015; 9:179-187.
Çimrin T. Thyme (Thymbra spicata L.), Rosemary (Rosmarinus officinalis L.) and vitamin E supplementation of laying hens. S Afr J Anim Sci. 2019; 49(5):914-921.
Hosseinzadeh S, Shariatmadari F, Ahmadi H, Scholey A, Amir Karimi Torshizi M. Plectranthus amboinicus and Rosemary (Rosmarinus officinalis L.) essential oil effects on performance, antioxidant activity, gut health, immune response and plasma biochemistry in broilers. Food Sci Nutr. 2023; 11(7):3939-3948.
Gumus R, Ercan N, Imik H. The effect of thyme essential oil (Thymus vulgaire) added to quail diets on performance, certain blood parameters and antioxidant metabolism of serum and liver tissue. Braz J Poult Sci. 2017; 19:297-304.
Abo Ghaniman MM, Elsadek MF, Taha AE, El-Hack A, Mohamed E, Alagawany M, Ahmed BM, Mona ME, El-Sabrout K. Effect of housing system and rosemary and cinnamon essential oils on layer performance, egg quality, hematological characteristics, blood chemistry, immunity and antioxidants. Anim (Basel). 2020; 10(2):245.
Seirafy H and Sobhanirad S. Effects of oregano (Origanum vulgare) and thyme (Thymus vulgaire) oils on growth performance and blood parameters in Holstein suckling calves. Iran J Appl Anim Sci. 2017; 7(4):585-593.
Khaksar V, Krimpen MV, Hashemipour H, Pilevar M. Effects of thyme essential oil on performance, some blood parameters and ileal microflora of Japanese quail. J Poult Sci. 2012; 25:201-210.
El-Ghousein SS and Al-Beitawi NA. The effect of feeding ground thyme (Thymus valgaris L.) on growth, blood constituents, gastrointestinal tract and carcass characteristics of broiler chickens. J Poult Sci. 2009; 46:100-104.
Elson CE. Suppression of mevalonate pathway activities by dietary isoprenoids: protective roles in cancer and cardiovascular disease. J Nutr. 1995; 125:1666-1672.
Mohammed HA, Alberta S, Nzélibé HC, Mahomet A, Erukainure OL, Musa B, Anigo MK. Bioactive fraction of Mentha piperita Leaf extract stimulates lipoprotein lipase at cellular and molecular levels via augmentation of antioxidant defense system in hyperlipidemic rats. J Herbs Spices Med Plants. 2021; 27:267-288.
Casseleux G and Buff S. Determination of the usual biochemical and haematological values of the 0-8 week old puppy. 2007.
Abdel-Ghaney DM, El-Far AlH, Sadek KM, El-Sayed, Yasser S, AbdelLatif Mervat A. Impact of Dietary Thyme (Thymus vulgaris) on Broiler Chickens Concerning Immunity, Antioxidant Status, and Performance. Alex J Vet Sci. 2017; 55(1):169-179.
Saleh N, Allam T, El-latif AA, Ghazy E. The effects of dietary supplementation of different levels of thyme (Thymus vulgaris) and ginger (Zingiber officinale) essential oils on performance, hematological, biochemical, and immunological parameters of broiler chickens. Global Vet. 2014; 12(6):736-744.
Safa SEG and AL-Beitawi NA. The effect of feeding of crushed thyme (Thymus valgaris) on growth, blood constituents, gastrointestinal tract, carcass characteristics of broiler chickens. J Poult Sci. 2009; 4:100-104.
Toghyani M, Tohidi M, Gheisari AA, Tabeidian SA. Performance, immunity, serum biochemical and hematological parameters in broiler chicks fed dietary thyme as alternative for an antibiotic growth promoter. Afr J Biotechnol. 2010; 9(40):6819-6825.
Sasaki K, Ama K, Tanaka Y, Yoshimura T, Matuoka K, Anno T. Thyme (Thymus vulgaire L.) leaves and constituents increase xenobiotic-metabolizing enzyme activities in mouse liver. activities of xenobiotic-metabolizing enzymes in mouse liver. J Méd Nourriture. 2005; 8:184-189.