Exploring the Phytochemical Composition and Pharmacological Activities of <i>Cerbera manghas <i>and <i>Cerbera odollam<i>: A Comprehensive Review

http://www.doi.org/10.26538/tjnpr/v8i1.1

Authors

  • Auliya Ilmiawati Department of Chemistry, Faculty of Mathematics and Natural Sciences, IPB University, Bogor, Indonesia
  • Ummahatul Mujahidah Department of Chemistry, Faculty of Mathematics and Natural Sciences, IPB University, Bogor, Indonesia
  • Arinana Department of Forest Products, Faculty of Forestry and Environment, IPB University, Bogor, Indonesia
  • Irmanida Batubara Department of Chemistry, Faculty of Mathematics and Natural Sciences, IPB University, Bogor, Indonesia
  • Waras Nurcholis Tropical Biopharmaca Research Center, IPB University, Bogor, Indonesia

Keywords:

Cerbera,, Cerbera manghas,, Cerbera odollam,, Pharmacological activities,, Phytochemicals

Abstract

Cerbera manghas and C. odollam, often perceived as similar species, exhibit distinct physical characteristics and phylogenetic classifications. Despite their reputation as poisonous plants, both species have diverse benefits and are potential sources of pharmacological compounds. This report comprehensively summarizes the compounds identified within the genus Cerbera, coupled with reported bioactivities. Over 100 compounds, including phenolics, flavonoids, terpenoids, and steroids, have been isolated from C. manghas and C. odollam. Cardiac glycosides (steroids) are the predominant compounds in these species and demonstrate robust cytotoxic activity.

Furthermore, both plants show promise as antioxidants and antimicrobial agents, and exhibit insecticidal, termiticidal, and larvicidal properties. This review consolidates the current understanding of the phytochemical and pharmacological attributes of C. manghas and C. odollam.

Author Biographies

Auliya Ilmiawati, Department of Chemistry, Faculty of Mathematics and Natural Sciences, IPB University, Bogor, Indonesia

Tropical Biopharmaca Research Center, IPB University, Bogor, Indonesia

Irmanida Batubara, Department of Chemistry, Faculty of Mathematics and Natural Sciences, IPB University, Bogor, Indonesia

Tropical Biopharmaca Research Center, IPB University, Bogor, Indonesia

Waras Nurcholis, Tropical Biopharmaca Research Center, IPB University, Bogor, Indonesia

Department of Biochemistry, Faculty of Mathematics and Natural Sciences, IPB University, Bogor, Indonesia

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2024-02-01

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Ilmiawati, A., Mujahidah, U., Arinana, Batubara, I., & Nurcholis, W. (2024). Exploring the Phytochemical Composition and Pharmacological Activities of <i>Cerbera manghas <i>and <i>Cerbera odollam<i>: A Comprehensive Review: http://www.doi.org/10.26538/tjnpr/v8i1.1. Tropical Journal of Natural Product Research (TJNPR), 8(1), 5715–5726. Retrieved from https://tjnpr.org/index.php/home/article/view/3364

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Vol. 8 No. 1 (2024): Tropical Journal of Natural Product Research (TJNPR)

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