Essential Oils of Origanum compactum: Antibacterial and Antioxidant Bioproducts http://www.doi.org/10.26538/tjnpr/v7i10.8

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Published: Oct 29, 2023
Keywords:
antibacterial, antioxidant, essential oil, Origanum compactum, GC-MS

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Ben El Jilali Sarah
Laboratory of Biology and Health, Ibn Tofil University, Kenitra, Morocco.
Beniaich Ghada
Department of Biology, Laboratory of Engineering, Electrochemistry, Modeling and Environment (LIEME), Faculty of Sciences Dhar EL Mahraz, USMBA, Fez, Morocco.
Ihamdane Rachid
Department of Chemistry, Organic Chemistry, Catalysis and Environment Laboratory, University Ibn Tofail, Kenitra, Morocco.
El abdali Youness
Laboratory of Biotechnology, Environment, Agrifood and Health, Faculty of Sciences Dhar El Mahraz, University of Sidi Mohamed Ben Abdellah, Fez 30050, Morocco.
Dardour Mohammed Mabchour Insaf
Laboratory of Plant, Animal and Agro-industry Productions, Faculty of Sciences, University of Ibn Tofail, Kenitra, Morocco.
Khadmaoui Abderrazzak
aboratory of Biology and Health, Ibn Tofil University, Kenitra, Morocco.

Abstract

Antibiotic resistance and oxidative stress are currently real threats to public health. Essential oils derived from aromatic plants are potential solutions to these health problems. In this context, the main objective of this study was to investigate the antioxidant and antibacterial properties of Moroccan oregano (Origanum compactum) essential oils (EOs). The EOs were extracted from the leaves and buds of the plant using the Clevenger apparatus. The oils obtained were characterized by GC-MS analysis. The EOs were also screened for antioxidants using the DPPH and TAC assays. Finally, the antibacterial activity of the EOs against some pathogenic microorganisms (Escherichia coli, Staphylococcus aureus, and Bacillus subtilis) was determined using the disk diffusion method. The GC-MS chromatographic analysis of the EOs derived from O. compactum (EOOC) revealed a high concentration of thymol and carvacrol as the predominant compounds in EOOC. The evaluation of EOOC's ability to scavenge DPPH radicals demonstrated a significant inhibition rate (IC50 = 0.235 mg/mL). Additionally, the measurement of total antioxidant capacity indicated the presence of a substantial amount of antioxidants in the oil (422.17 ± 22.53 mg EAA/g of EO). The antibacterial results displayed a higher efficacy of EOOC against the tested pathogenic bacteria, particularly S. aureus MIC = 0.751 µl/mL). From the experimental results obtained, the EO of Moroccan Origanum compactum contained eco-friendly antimicrobials and antioxidants and can constitute a promising agent to combat the issues of resistance to conventional drugs and ineffective drug usage.

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How to Cite
Sarah, B. E. J., Ghada, B., Rachid, I., Youness, E. abdali, Mabchour Insaf, D. M., & Abderrazzak, K. (2023). Essential Oils of Origanum compactum: Antibacterial and Antioxidant Bioproducts: http://www.doi.org/10.26538/tjnpr/v7i10.8. Tropical Journal of Natural Product Research (TJNPR), 7(10), 4166-4170. https://tjnpr.org/index.php/home/article/view/2796
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Vol. 7 No. 10 (2023): Tropical Journal of Natural Product Research (TJNPR)
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Articles
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This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

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