Cytotoxic Activity of Xanthones from the Stem Bark of Cratoxylum sumatranum http://www.doi.org/10.26538/tjnpr/v7i9.9
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Abstract
Two xanthones, gerontoxanthone I and macluraxanthone, were isolated from the stem bark of Cratoxylum sumatranum. Their structures were determined based on UV, HRESI-MS, 1D, and 2D NMR spectral data. Compounds 1 and 2 showed high activity against T47D cells with an IC50 of 1.10 and 1.60 μg/mL.
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