Antibiotic Resistance Pattern of Uropathogenic Escherichia coli Identified in a Healthcare Laboratory (Morocco) http://www.doi.org/10.26538/tjnpr/v7i8.4
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Abstract
Urinary tract infection is one of the most common infectious diseases worldwide. This study aimed to determine the frequency of Urinary tract infections, identify the microorganisms involved, and determine the antibiotic resistance pattern of Escherichia coli. Conventional biochemical techniques identified isolates. The antibiogram was produced using the Muller-Hinton agar disc diffusion method according to the recommendations of the Antibiotic Committee of the French Microbiology Society. During the study period, 21. 4% of the samples were identified as positive. The microorganisms isolated were: Escherichia coli (47%), Klebsiella pneumoniae (19%) followed by Trichomonas vaginalis (9%), Candida albicans, and Pseudomonas sp (8%). Finally, Staphylococcus aureus and Proteus rettgeri represent 4% of isolates. The dominant resistance of E.coli was to amoxicillin and ticarcillin (55%) followed by cefalotine (39%). Resistance to fluoroquinolones was 27% (norfloxacin). The amikacin and gentamicin resistance rates were 12.5%, and 10.5% respectively. The resistance to the third-generation cephalosporins (ceftazidime, cefotaxime) was 10.5%. E. coli were resistant to nitrofurantoin and fosfomycin with percentages of 10.5%, and 6.6% respectively. However, the resistance to imipenem does not
exceed 2%. Increasing rates of E.coli antibiotic resistance indicate that careful monitoring of their use is necessary.
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