Antibiotic Resistance Pattern of Uropathogenic Escherichia coli Identified in a Healthcare Laboratory (Morocco)

http://www.doi.org/10.26538/tjnpr/v7i8.4

Authors

  • Samira Jaouhar Laboratory of Microbial Biotechnology & Bioactive Molecules, Faculty of Sciences and Techniques, Sidi Mohamed Ben Abdellah University, PB 2202, Fez, Morocco.
  • Jawad Bouzid Hassan First University of Settat, Higher Institute of Health Sciences; Laboratory of Health Sciences and Technologies; Casablanca Road km 3,5 PB 555 Settat;26000; Morocco.
  • Mohammed Maoulouaa Laboratory of medical analyses of Meknes’ Hospital, Health Regional Direction of Fez-Meknes. Morocco.
  • Zhour Elasraouy Higher Institut of Nursing and Health Professions of Fez-Meknes. Regional Directorate of Health Fes-Meknes, El Ghassani Hospital, Dhar El Mehraz, 30000, Fes, Morocco.
  • Fatima-Zahra Motya Higher Institut of Nursing and Health Professions of Fez-Meknes. Regional Directorate of Health Fes-Meknes, El Ghassani Hospital, Dhar El Mehraz, 30000, Fes, Morocco.
  • Najia El Hamzaoui Laboratory of medical analyses of Meknes’ Hospital, Health Regional Direction of Fez-Meknes. Morocco.
  • Khadija Ouarrak Laboratory of medical analyses of Meknes’ Hospital, Health Regional Direction of Fez-Meknes. Morocco.
  • Khadija Bekhti Laboratory of Microbial Biotechnology & Bioactive Molecules, Faculty of Sciences and Techniques, Sidi Mohamed Ben Abdellah University, PB 2202, Fez, Morocco.

Keywords:

Urinary Tract Infection, Escherichia coli, Antibiotics, Resistance

Abstract

Urinary tract infection is one of the most common infectious diseases worldwide. This study aimed to determine the frequency of Urinary tract infections, identify the microorganisms involved, and determine the antibiotic resistance pattern of Escherichia coli. Conventional biochemical techniques identified isolates. The antibiogram was produced using the Muller-Hinton agar disc diffusion method according to the recommendations of the Antibiotic Committee of the French Microbiology Society. During the study period, 21. 4% of the samples were identified as positive. The microorganisms isolated were: Escherichia coli (47%), Klebsiella pneumoniae (19%) followed by Trichomonas vaginalis (9%), Candida albicans, and Pseudomonas sp (8%). Finally, Staphylococcus aureus and Proteus rettgeri represent 4% of isolates. The dominant resistance of E.coli was to amoxicillin and ticarcillin (55%) followed by cefalotine (39%). Resistance to fluoroquinolones was 27% (norfloxacin). The amikacin and gentamicin resistance rates were 12.5%, and 10.5% respectively. The resistance to the third-generation cephalosporins (ceftazidime, cefotaxime) was 10.5%. E. coli were resistant to nitrofurantoin and fosfomycin with percentages of 10.5%, and 6.6% respectively. However, the resistance to imipenem does not
exceed 2%. Increasing rates of E.coli antibiotic resistance indicate that careful monitoring of their use is necessary. 

Author Biography

Samira Jaouhar, Laboratory of Microbial Biotechnology & Bioactive Molecules, Faculty of Sciences and Techniques, Sidi Mohamed Ben Abdellah University, PB 2202, Fez, Morocco.

Higher Institut of Nursing and Health Professions of Fez-Meknes. Regional Directorate of Health Fes-Meknes, El Ghassani Hospital, Dhar El Mehraz, 30000, Fes, Morocco.


Hassan First University of Settat, Higher Institute of Health Sciences; Laboratory of Health Sciences and Technologies; Casablanca Road km 3,5 PB 555 Settat; 26000; Morocco.

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Published

2023-08-31

How to Cite

Jaouhar, S., Bouzid, J., Maoulouaa, M., Elasraouy, Z., Motya, F.-Z., Hamzaoui, N. E., … Bekhti, K. (2023). Antibiotic Resistance Pattern of Uropathogenic Escherichia coli Identified in a Healthcare Laboratory (Morocco): http://www.doi.org/10.26538/tjnpr/v7i8.4. Tropical Journal of Natural Product Research (TJNPR), 7(8), 3602–3605. Retrieved from https://tjnpr.org/index.php/home/article/view/2397

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