Pulmonary Tuberculosis in Hospital Setting: Retrospective Study on Risk Factors http://www.doi.org/10.26538/tjnpr/v7i7.14
Main Article Content
Abstract
Pulmonary tuberculosis is an airborne disease when people with tuberculosis cough up tuberculosis bacilli into the air. It is a serious public health problem in developing countries. In Morocco, the clinical management of pulmonary tuberculosis is often ambulatory, and hospitalization is indicated only for severe or complicated cases. This study aims to investigate the risk factors associated with pulmonary tuberculosis in patients hospitalized. A retrospective study was conducted on patients with pulmonary tuberculosis hospitalized in the pulmonology department from January 1, 2019 to June 1, 2021. Data were extracted from tuberculosis patients' records and statically analyzed using SPSS software. A total of 140 cases of pulmonary tuberculosis were identified with a predominance of the male gender (90.71%). The age category between 15 and 34 years was the most affected by the disease (p=0.017). The bivariate analysis showed that there are apparent risk factors for the disease. Most of the patients who developed the disease were smokers (p=0.035) of the male gender (p=0.003). There was a significant association between the disease and HIV-positive status (p=0.001). In addition, diabetic patients were also predisposed to develop the disease (p=0.002). In conclusion, young and male patients were more likely to be affected by the disease. Smoking, contact with a person with tuberculosis, and comorbidity with the disease were found to be risk factors for developing lung disease. This calls for intensified screening activities for tuberculosis in active patients.
Article Details
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
References
World Health Organization. Global tuberculosis report. World Health Organization. 2022. https://www.who.int/publications-detailredirect/9789240061729
Ali, S. M., & Rehal, S. Public health practitioners’ perspective on the sustainability of the tuberculosis control programme at primary health care level in Pakistan. East Mediterr Health J. 2021; 27(9):899‑905. Doi.org/10.26719/emhj.21.044
Desalegn, D. M., Kitila, K. T., Taddese, B. D., Hailu, T. K., Dinku, T. T., Asferie, K. D., Balcha, H. M., Gebeyehu, C. S., & Medhin, G. Sputum Smear Positive Pulmonary Tuberculosis Diagnostic Dropout Rate in Public Health Facilities, Addis Ababa, Ethiopia. Pulmonary Medicine. 2019; e2905615. Doi.org/10.1155/2019/2905615
World Health Organization. WHO operational handbook on tuberculosis : Module 5: management of tuberculosis in children and adolescents. 2022. https://www.who.int/publications-detailredirect/9789240046832
Abdu M., Balchut A, Girma E, Mebratu W. Patient Delay in Initiating Tuberculosis Treatment and Associated Factors in Oromia Special Zone, Amhara Region. Pulmonary Medicine, 2020, e6726798. Doi.org/10.1155/2020/6726798.
Singla, R, Raghu, B, Gupta A, Caminero JA, Sethi P, Tayal, D, Chakraborty A, Jain Y, Migliori GB. Risk factors for early mortality in patients with pulmonary tuberculosis admitted to the emergency room. Pulmonology. 2021. 27(1), 35‑42.
Doi.org/10.1016/j.pulmoe.2020.02.002
Rahem A, Priyandani,Y, Djunaedi M. The Correlation between Belief and Adherence to Therapeutic Regimens in Pharmaceutical Care for Tuberculosis Patients in Primary Healthcare Centres in Surabaya, Indonesia. Trop J Nat Prod
Res. 2020; 4(8), Article 8. Doi.org/10.26538/tjnpr/v4i8.6
Eddabra, R., & Neffa, M. Epidemiological profile among pulmonary and extrapulmonary tuberculosis patients in
Laayoune, Morocco. The Pan African Medical J. 2020. 37(56), Article 56. Doi.org/10.11604/pamj.2020.37.56.21111
Tachfouti N, Nejjari C, Benjelloun MC, Berraho M., Elfakir S, El Rhazi, K, Slama, K. Association between smoking status, other factors and tuberculosis treatment failure in Morocco. International Union Against Tuberculosis and Lung Disease. 2011. 15(6).838-843. Doi.org/10.5588/ijtld.10.0437
Akrim M, Bennani K, Essolbi, A, Sghiar M, Likos A., Benmamoun A, El Menzhi O, Maaroufi A. Determinants of
consultation, diagnosis and treatment delays among new smear-positive pulmonary tuberculosis patients in Morocco :
A cross-sectional study. East Mediterr Health J. 2014. 20(11):707‑716. Doi.org/10.26719/2014.20.11.707.
Ministry of Health and Welfare. National Program for Tuberculosis Control: Management of tuberculosis in children, adolescents and adults. Algorithms and standard operating procedures (AZ Editions - Rabat). Directorate of Epidemiology and Disease Control. 2020. https://www.sante.gov.ma/Documents/Prise-en-charge-dela-TB.pdf
Makori L, Gichana H, Oyugi E, Nyale G, Ransom J. Tuberculosis in an urban hospital setting : Descriptive epidemiology among patients at Kenyatta National Hospital TB clinic, Nairobi, Kenya. In J of Africa Nursing Sciences (IJANS). 2021; 15:100308. Doi.org/10.1016/j.ijans.2021.100308.
Birhan, H., Seyoum, A., Derebe, K., Muche, S., Wale, M., & Sisay, S. Joint clinical and socio-demographic determinants of CD4 cell count and body weight in HIV/TB co-infected adult patients on HAART. Scientific African. 2022; 18, e01396. Doi.org/10.1016/j.sciaf.2022.e01396
Furuuchi, K., Morimoto, K., Yoshiyama, T., Tanaka, Y., Fujiwara, K., Okumura, M., Izumi, K., Shiraishi, Y., Mitarai, S., Ogata, H., Kurashima, A., Yoshimori, K., Ohta, K., Goto, H., & Sasaki, Y.. Interrelational changes in the epidemiology and clinical features of nontuberculous mycobacterialJapan. Respiratory Medicine. 2019; 152, 74‑80. doi.org/10.1016/j.rmed.2019.05.001.
Siranart, N., Sowalertrat, W., Sukonpatip, M., Suwanpimolkul, G., & Torvorapanit, P. First case series and literature review of coronavirus disease 2019 (COVID-19) associated pulmonary tuberculosis in Southeast Asia : Challenges and opportunities. Journal of Infection and Public Health, 2023; 16(1), 80‑89. doi.org/10.1016/j.jiph.2022.11.029
Department of Health. Figures on health. Department of Planning and Financial Resources Planning and Studies Division Health Studies and Information Department. 2020; https://www.sante.gov.ma/Documents/2022/11/Sante%20en%20chiffres%202020%20VF.pdf
Yague-Santiago, Z. L., Ramírez-Díaz, M. del P., Ramírez, D. D. V.-, Zenteno-Cuevas, R., & Luna-Hernández, J. F. Factors
associated with tuberculosis-diabetes mellitus type 2 binomial in rural population of Oaxaca, Mexico. The Journal of Infection in Developing Countries. 2022; 16(04), Article 04. Doi.org/10.3855/jidc.15543
Hikone, M., Ainoda, Y., Sakamoto, N., & Ohnishi, K. Clinical characteristics of elderly pulmonary tuberculosis in an acute-care general hospital in Tokyo, Japan : A 12-year retrospective study. J Infection and Chemotherapy; 2020. 26(3), 245‑250. doi.org/10.1016/j.jiac.2019.09.009
Wang, C.-S., Chen, H.-C., Yang, C.-J., Tsai, J.-R., Chong, I.- W., Hwang, J.-J., & Huang, M.-S. Clinical Characteristics of Pulmonary Tuberculosis Patients from a Southern Taiwan Hospital-based Survey. The Kaohsiung J Medical Sci. 2008;
(1), 17‑24. doi.org/10.1016/S1607-551X(08)70068-8
Bayabil, S., & Seyoum, A. Joint Modeling in Detecting Predictors of CD4 Cell Count and Status of Tuberculosis Among People Living with HIV/AIDS Under HAART at Felege Hiwot Teaching and Specialized Hospital, NorthWest Ethiopia. HIV/AIDS - Research and Palliative Care.2021; 13, 527‑537. doi.org/10.2147/HIV.S307069
22. Birhan, H., Derebe, K., Muche, S., & Melese, B. Statistical Analysis on Determinant Factors Associated with Time to
Death of HIV/TB Co-Infected Patients Under HAART at Debre Tabor Referral Hospital : An Application of Accelerated Failure Time-Shared Frailty Models. HIV/AIDS - Research and Palliative Care. 2021. 13, 775‑ 787. doi.org/10.2147/HIV.S319745
Ali, Z. A., Al-Obaidi, M. J., Sameer, F. O., Mankhi, A. A., Misha’al, K. I., Jassim, I. A., Taqi, E. A., & Ad’hiah, A. H.
Epidemiological profile of tuberculosis in Iraq during 2011– 2018. Indian J Tuberculosis. 2022; 69(1), 27‑34. https://doi.org/10.1016/j.ijtb.2021.01.003
Barry, M. Prevalence of Latent Tuberculosis Infection in the Middle East and North Africa : A Systematic Review.
Pulmonary Medicine. 2021; e6680651. https://doi.org/10.1155/2021/6680651.
El-Mouhdi K, Dahmani F, Lhilali I, Zouine N, Chahlaoui A, Fekhaoui M, Boussaa S. Perception and use of Medicinal
Plants and Chemical Products in the Traditional Treatment of Cutaneous Leishmaniasis in Morocco. Trop J Nat Prod
Res. 2023; 7(5):2946-2951 http://www.doi.org/10.26538/tjnpr/v7i5.16
El-Mouhdi, K., Et-tayyeby, K., Dahmani, F., Milouk, F. Z., & El Ouali Lalami, A. (2023). Training Based on Simulation
Pedagogy : Evaluation of Participants’ Satisfaction with the First National Forum on Simulation in Nursing in Morocco.
Nursing Forum. 2023; e2553516. doi.org/10.1155/2023/2553516 pulmonary disease and tuberculosis in a referral hospital in