Chemical Constituents and Biological Activities of Commersonia bartramia Stems http://www.doi.org/10.26538/tjnpr/v7i6.13

Main Article Content

Kieu C. Nhung
Tran T. Bach
Vu T. Hue
Bui T. Ha
Le N. Thanh

Abstract

Commersonia bartramia (Sterculiaceae family) is a wooden tree, widely occurring in Australia, China and South East Asia. The MeOH extract of C. bartramia has been reported to show anticancer and antioxidant activities. Phytochemical investigation of C. bartramia stems led to the isolation of eight compounds. Their chemical structures were identified as helichrysoside-3′- methyl ether (1), tiliroside (2), pinoresinol (3), ursolic acid (4), quercetin (5), kaempferol (6), vanillic acid (7) and 4-hydroxybenzoic acid (8) using NMR and MS spectral analysis. This is the first study about the chemical composition of C. bartramia. Among the isolated compounds, quercetin (5) showed good DPPH’s radical scavenging activity with IC50 values of 11.43 ± 0.95 g/mL, whereas the MeOH extract, (+)-pinoresinol (3) and kaempferol (6) displayed moderate activity. Quercetin (5) also displayed moderate cytotoxicity with IC50 values of 43.64 ± 3.63 to
61.58 ± 5.54 g/mL. The MeOH extract exhibited weak cytotoxicity against HepG2, MCF7 and A549 cell lines.

Article Details

How to Cite
Nhung, K. C., Bach, T. T., Hue, V. T., Ha, B. T., & Thanh, L. N. (2023). Chemical Constituents and Biological Activities of Commersonia bartramia Stems: http://www.doi.org/10.26538/tjnpr/v7i6.13. Tropical Journal of Natural Product Research (TJNPR), 7(6), 3147–3152. Retrieved from https://tjnpr.org/index.php/home/article/view/2090
Section
Articles
Author Biographies

Kieu C. Nhung, Graduate University of Science and Technology, Vietnam Academy of Science and Technology, 18 Hoang Quoc Viet, Caugiay, Hanoi 10000, Vietnam

Ministry of Science and Technology, Hanoi 10000, Vietnam

Tran T. Bach, Graduate University of Science and Technology, Vietnam Academy of Science and Technology, 18 Hoang Quoc Viet, Caugiay, Hanoi 10000, Vietnam

Institute of Ecology and Biological Resources, Vietnam Academy of Science and Technology, 18 Hoang Quoc Viet, Caugiay, Hanoi 10000, Vietnam

Vu T. Hue, Institute of Marine Biochemistry, Vietnam Academy of Science and Technology, 18 Hoang Quoc Viet, Caugiay, Hanoi 10000, Vietnam

Faculty of Biology, Hanoi National University of Education, Hanoi 10000, Vietnam

Le N. Thanh, Graduate University of Science and Technology, Vietnam Academy of Science and Technology, 18 Hoang Quoc Viet, Caugiay, Hanoi 10000, Vietnam

Institute of Marine Biochemistry, Vietnam Academy of Science and Technology, 18 Hoang Quoc Viet, Caugiay, Hanoi 10000, Vietnam

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