Anti-UV, SPF, and Antibacterial Activities of Gorgonian Mopsella cf. aurantia http://www.doi.org/10.26538/tjnpr/v7i5.5
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Abstract
Gorgonia is one of the marine organisms with bioactive potential that has yet to be widely exploited. This research aimed to determine the anti-UV, the Sun Protection Factor (SPF), and antibacterial properties of the extract and fractions of gorgonian Mopsella cf. aurantia. The extraction was carried out using ethyl acetate as a solvent. The anti-UV and SPF determinations were carried out by ultraviolet spectrophotometry, while the antibacterial property was carried out using the modified Kirby-Bauer method. The result shows that the extract has anti-UVB activity and obtained an SPF value of 7.71 at a concentration of 250 ppm, which is categorized as a
minimal level of protection capability. Further bioactivity testing of this gorgonian shows robust activity against Gram-negative Escherichia coli DSM498 and Gram-positive Bacillus megaterium DSM32T strains. The antimicrobial and anti-UV effects in the related species were located in the ethanol fraction.
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References
Wood R, Veron JEN. Corals in Space & Time. The Biogeography & Evolution of the Scleractinia. xiii + 321 pp. Geol Mag. 1996; 133.
Proksch P, Edrada R, Ebel R. Drugs from the seas - current status and microbiological implications. Appl Micr Biotech. 2002; 59.(2): 125.
Bara RA, Tandiongan M, Sondak CFA, Posangi I, Angkouw E, Losung F, Angmalisang PA, Sambali H, Posangi J. Toxicity and Antibacterial Activity of ascidian Eudistoma cf. purpuropuctatum. Int J Pharm Bio Med Sci. 2022; 2.(4):57- 66.
Datula’bi JS, Bara RA, Losung F, Mangindaan REP, Angmalisang PA, Mantiri ROSE. Cytotoxic activity of soft coral extract Xenia sp. From Manado Bay, North Sulawesi Province. J PES. L. TROP. 2021; 9.(3): 66-73.
Mishra N, Gupta E, Walag AMP, Kharwar RN, Singh P, Mishra P. A Review of Marine Natural Product Resources with Potential Bioactivity Against SARS-COV-2. Trop J Nat Prod Res. 2023; 7.(1):2093-2103.
Widjhati R, Supriyono A, Subintoro. Development of Bioactive Compounds from Marine Biota. BPPT. 2004.
Saibu GM, Vincent NM, Omowunmi OA, Opeoluwa OO, Olawale FO, Meyer M. In-vitro Cytotoxicity, Anti-bacterial and Anti-inflammatory Activities of Ecklonia radiata and Jania verrucosa from Eastern Cape, South Africa. Trop J Nat Prod Res. 2023; 7.(1):2122-2127.
Blunt JW, Copp BR, Keyzers RA, Munro MH, Prinsep MR. Marine natural products. Nat Prod Rep. 2015; 32.(2):116-211.
Pawlik JR. Marine invertebrate chemical defenses. Chem Rev. 1993; 93.(5):1911-1922.
Pawlik JR, Burch MT, Fenical WJJoEMB, Ecology. Patterns of chemical defense among Caribbean gorgonian corals: a preliminary survey. 1987; 108.(1):55-66.
Bright-Diaz LM, Strychar KB, Shirley T. Compounds from deep-sea bubblegum corals, Paragorgia arborea, elicit antipredation behavior in fish. O Mar Biol J. 2011; 5:58-67.
Gerhart D. Prostaglandin A-2 an agent of chemical defense in the Caribbean gorgonian Plexaura homomalla. Mar Ecol Prog Ser. 1984; 19:181-187.
Maia LF, Epifanio RdA, Eve T, Fenical W. New fish feeding deterrents, including a novel sesquiterpenoid heterogorgiolide, from the Brazilian gorgonian Heterogorgia uatumani (Octocorallia, Gorgonacea). J Nat Prod. 1999; 62.(9): 1322-1324.
Strobel G, Daisy B, Castillo U, Harper J. Natural Products from Endophytic Microorganisms. J Nat Prod. 2004; 67.(2): 257-268.
Wagenaar MM, Corwin J, Strobel G, Clardy J. Three New Cytochalasins Produced by an Endophytic Fungus in the Genus Rhinocladiella. J Nat Prod. 2000; 63.(12):1692-1695.
Wang F, Hou Z, Wang C, Li P, Shi D. Bioactive metabolites from Penicillium sp., an endophytic fungus residing in Hopea hainanensis. W J Micr Biotech. 2008; 24.(10): 2143-2147.
Warouw F, Mambo C, Pertiwi JM, Warouw V, Bara RA. Identification of Active Antioxidant Compounds with Neuroprotective Effects in Kora-kora Coastal Macro-algae. Trop J Nat Prod Res. 2022; 6.(12): 2025-2028.
Kumar S, Kaushik N, Edrada-Ebel R, Ebel R, Proksch P. Endophytic Fungi for Pest and Disease Management, in Integrated Management of Diseases Caused by Fungi, Phytoplasma and Bacteria. 2008; 365-387.
Pabel CT, Vater J, Wilde C, Franke P, Hofemeister J, Adler B, Bringmann G, Hacker J, Hentschel U. Antimicrobial activities and matrix-assisted laser desorption/ionization mass spectrometry of Bacillus isolates from the marine sponge Aplysina aerophoba. Mar Biotechnol (NY). 2003; 5.(5): 424-34.
Iwamaru A, Iwado E, Kondo S, Newman RA, Vera B, Rodríguez AD, Kondo Y. Eupalmerin acetate, a novel anticancer agent from Caribbean gorgonian octocorals, induces apoptosis in malignant glioma cells via the c-Jun NH2-terminal kinase pathway. Mol Canc Ther. 2007; 6.(1): 184-92.
Kjer J, Debbab A, Aly AH, Proksch P. Methods for isolation of marine-derived endophytic fungi and their bioactive secondary products. Nat Prot. 2010; 5.(3):479-90.
Pratama WA, Zulkarnain AK. In Vitro Spf Test And Physical Properties Of Some Market Sunscreen Products. Majalah Farmaseutik. 2015; 11.(1):275-283.
Mansur JdS, Breder MNR, Mansur MCdA, Azulay RD. Determinaçäo do fator de proteçäo solar por espectrofotometria/Determination of sun protection factor by spectrophotometry. An Bras Derma 1986; 61.(3):121-4.
Dutra E, Oliveira D, Kedor-Hackmann E, Santoro M. Determination of sun protection factor (SPF) of sunscreens by ultraviolet spectrophotometry. Revista Brasileira de Ciências Farmacêuticas. 2004; 40.(3):381-385.
U.S. FDA. Title 21-Food and Drugs. Chapter 1-Food and Drug Administration. Part 352 Sunscreen Drug Products For Over-The-Counter Human Use 2023 12 April 2023]; Available from: https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CF RSearch.cfm?CFRPart=352&showFR=1.
Lisnawati N, Fathan M, Nurlitasari D. Determination of Spf Value of Ethyl Acetate Extract of Mango Leaves Using Uv - Vis Spectrophotometry. J Ris Kefarm Ind. 2019; 1.(2):157- 165.
Purwaningsih S, Salamah E, Adnin. MN. Photoprotective Effect Of Sunscreen Cream With The Addition Of Carraginan And Mangrove Fruit Rhizopora Mucronata Lamk. J I Tekn Kel Trop. 2015; 7.(2):1-14.
Davis WW, Stout TR. Disc plate method of microbiological antibiotic assay. I. Factors influencing variability and error. Appl Microbiol. 1971; 22.(4):659-65.
Pratiwi R, Budiman S, Hadisoebroto G. Penetapan Kadar Nilai Spf (Sun Protection Factor) Dengan Menggunakan Spektrofotometri Uv-Vis Pada Krim Pencerah Wajah Yang Mengandung Tabir Surya Yang Beredar Di Kota Bandung. Pros Sem Nas Kim UNJANI. 2016.
World Health O. Antimicrobial Resistance: Global Report on Surveillance. 2014, Geneva: WHO.
Putri NMMS, Kandou F, Singkoh M. Phytochemical screening test the antibacterial bioactivity of gorgonia Mopsella sp. *cf, Siphonogorgia sp. and Villogorgia sp. Againts Pseudomonas aeruginosa and Bacillus cereus. J Bios Logos. 201; 9(2):83-90.
Jensen PR, Harvell CD, Wirtz K, Fenical W. Antimicrobial activity of extracts of Caribbean gorgonian corals. Mar Biol. 1996; 125.(2):411-419.
Poole K. Efflux Pumps as Antimicrobial Resistance Mechanisms. Ann Med. 2007; 39.(3):162-76.
Posangi J, Bara RA. Analysis of the activity of endophytic fungi found in the mangroves Avicennia marina in Tasik Ria Minahasa. J Pes L Trop. 2014; 1.(1):30-38.