Exploration of Phytochemical and Sun Protection Efficacy of Anthocephalus chinensis Leaves Extracts



  • Zulphikar Ali AVIPS, Shobhit university, Gangoh, Uttar Pradesh, India.
  • Sudhakar Kaushik SPS, Shri guru ram rai university, Dehradun, Uttarakhand, India
  • Ranjit Singh AVIPS, Shobhit university, Gangoh, Uttar Pradesh, India.
  • Bhawana Bhatt SPS, Shri guru ram rai university, Dehradun, Uttarakhand, India


Plant extracts, Mansur equation, Ultraviolet radiation, Sun protection factor, Anthocephalus chinensis


Overexposure to UV light can cause negative physical conditions for example sear, blot, skin maturing, and cancer of the skin. Using photoprotective or multifunctional products on a daily basis can help to mitigate these harmful health effects. Worries regarding skin protection, communal ramifications, and ethical trading possess increased industry attention in adding natural components into commercial products. Many investigations are presently working on extracts of herbs, however Anthocephalus chinensis is still understudied and underutilized. The study attempts to explore Anthocephalus chinensis phytochemical composition and sun-protective abilities. The leaves of Anthocephalus chinensis were extracted with petroleum ether, water, and ethanol employing the cold-maceration approach. An initial phytochemical search of the leaves extracts of Anthocephalus chinensis has been carried out. The UV spectroscopic method has been employed to assess the sun-protective capacity of the various Anthocephalus chinensis extracts. The outcomes of the phytochemical search discovered the existence of alkaloids and glycosides in all the Anthocephalus chinensis leaves extracts, whereas flavonoids were found only in water and ethanol extract. The sun protective abilities of the various extracts was detected to be 2.27±0.022, 1.57±0.003, and 0.70±0.006 for the ethanol, water, and petroleum ether extracts, respectively. Current work conclusions suggest that extracts of Anthocephalus chinensis leaves might be used to produce photoprotective preparations.


Agour A, Mssillou I, Saghrouchni H, Bari A, Lyoussi B and Derwich E. Chemical Composition, Antioxidant Potential and Antimicrobial Properties of the Essential Oils of Haplophyllum tuberculatum (Forsskal) A. Juss from Morocco. Trop J Nat Prod Res. 2020; 4(12):1108-1115.

Mondal S, Bhar K, Mahapatra AS, Mukherjee J, Mondal P, Rahaman ST, Nair AP. “Haripriya” God’s Favorite: Anthocephalus cadamba (Roxb.) Miq.-At a Glance. Pharmacog Resea. 2020;12(1):1-16.

Dupont E, Gomez J, Bilodeau D. Beyond UV radiation: a skin under challenge. Int J Cos Sci. 2013;35(3):224-32.

Bhatt B, Chaurasia H, Singh R, Kaushik S. Phytochemical Profile and in vitro Sun-Protective Activity of Polyalthia longifolia (Sonn.) Thwaites Bark Extracts. Trop J Nat Prod Res. 2022; 6(8):1174-1177.

Almeida WA, Antunes AD, Penido RG, Correa HS, Nascimento AM, Andrade ÂL, Santos VR, Cazati T, Amparo TR, Souza GH, Freitas KM. Photoprotective activity and increase of SPF in sunscreen formulation using lyophilized red propolis extracts from Alagoas. Rev. Bras. de Farmacog. 2019;29:373-80.

Catelan TB, Gaiola L, Duarte BF, Cardoso CA. Evaluation of the in vitro photoprotective potential of ethanolic extracts of four species of the genus Campomanesia. J Photochem Photobiol. : Bio. 2019;197:111500.

Diffey BL, Tanner PR, Matts PJ, Nash JF. In vitro assessment of the broad-spectrum ultraviolet protection of sunscreen products. J Amer Acad Derma. 2000;43(6):1024-35.

Sutar MP, Chaudhari SR. Screening of in vitro sun protection factor of some medicinal plant extracts by ultraviolet spectroscopy method. J App Bio Biotech. 2020;8(6):48-53.

Kumar V, Pal M, Dhiman N. Determination of sun protection factor in different extract of Eulaliopsis Binata. Plant Arc. 2019;19(2):185-7.

Cefali LC, Ataide JA, Fernandes AR, Sanchez-Lopez E, Sousa IM, Figueiredo MC, Ruiz AL, Foglio MA, Mazzola PG, Souto EB. Evaluation of in vitro solar protection factor (SPF), antioxidant activity, and cell viability of mixed vegetable extracts from Dirmophandra mollis Benth, Ginkgo

biloba L., Ruta graveolens L., and Vitis vinífera L. Plants. 2019;8(11):1-13.

Fardiyah Q, Ersam T, Slamet A, Kurniawan F. New potential and characterization of Andrographis paniculata L. Ness plant extracts as photoprotective agent. Arab J Chem. 2020;13(12):8888-97.

Namukobe J, Sekandi P, Byamukama R, Murungi M, Nambooze J, Ekyibetenga Y, Nagawa CB, Asiimwe S. Antibacterial, antioxidant, and sun protection potential of selected ethnomedicinal plants used for skin infections in Uganda. Trop Med Health. 2021; 49(1):1-10.

Khazaeli P, Mehrabani M. Screening of sun protective activity of the ethyl acetate extracts of some medicinal plants. Iran J Pharma Res. 2010;20(1):5-9.

Ratnasooriya WD, Pathirana RN, Dissanayake AS, Samanmali BL, Desman PK. Evaluation of invitro sun screen activities of salt marshy plants Suaeda monoica, Suaeda maritima and Halosarcia indica. Inter J Pharma Res All Sci. 2016;5(2):15-20.

Dubey A, Nayak S, Goupale DC. A review on phytochemical, pharmacological and toxicological studies on Neolamarckia cadamba. Der. Pharm. Let. 2011;3:45-54.

Naryan S, Bhumarkar H. A Review on: Pharmacological activity of Anthocephalus cadamba. Wor J Pharma Res. 2018;7(16):383-94.

Kumar V. Medicinal properties of Anthocephalus indicus(Kadam): an indigenous medicinal plant. EJMR. 2017;4(1):63-7.

Das BP, Ghosh A. Medicinal properties of phyto-constituents from Rubiaceae family of Assam: Critical Review. Inter J App Chem Bio Sci. 2020;1(3):1-25.

Umachigi SP, Kumar GS, Jayaveera KN, Dhanapal R. Antimicrobial, wound healing and antioxidant activities of Anthocephalus cadamba. Afr J Trad, Comp Alt Med. 2007;4(4):481-7.

Priyanka N, Srikanth M, Babu GR, Sowjanya M, Sri VR, Vasanthi M, Bhargavi K, Tirupathaiah Y, Vasavi K, Raviteja N. In-vitro Screening of Anti-microbial, Anti-fungal and Anti-oxidant activities of Ethanolic leaf extract of Anthocephalus cadamba. Asian J Pharma Res. 2022;12(4):275-80.

Ali S, Ishteyaque S, Khan F, Singh P, Soni A, Mugale MN. Accelerative wound-healing effect of aqueous Anthocephalus cadamba leaf extract in a diabetic rat model. Inter J Low Ext Wounds. 2021:1-9.

Zahan T, Khatun L, Siddika A, Nime MJ, Habib MR, Aziz MA. Evaluation of antioxidant, cytotoxic and antimicrobial potentials of Anthocephalus cadamba (Roxb.) leaves. J Pharm Chem Biol Sci. 2019;7:157-63.

Ang AM, Uyangurin IE. Antioxidant potential of the ethanol, ethyl acetate and petroleum ether extracts of Kyllinga nemoralis. Int J Biosci. 2022;20(4):59-69.

Sneha P, Bharti F, Urvashi Z, Bhaskar VH. Determination of sun protection effect of herbal sunscreen cream. Wor J Phar Pharmaceu Sci (WJPPS). 2015;4(8):1554-65.

Kalaiselvi V, Binu TV, Radha SR. Preliminary phytochemical analysis of the various leaf extracts of Mimusops elengi L. South Ind. J. Biol. Sci. 2016; 2:24-9.

Ramamurthy V, Sathiyadevi M. Preliminary phytochemical screening of methanol extract of Indigotera trita Linn. J. Plant Biochem. Physiol. 2017; 5(2):1-3.

Miri A, Akbarpour Birjandi S, Sarani M. Survey of cytotoxic and UV protection effects of biosynthesized cerium oxide nanoparticles. J Biochem Mol Toxicol. 2020; 34(6):1-6.

Costa SC, Detoni CB, Branco CR, Botura MB, Branco A. In vitro photoprotective effects of Marcetia taxifolia ethanolic extract and its potential for sunscreen formulations. Rev Bras de Farma. 2015; 25:413-8.

Mbanga L, Mpiana PT, Mbala M, Ilinga L, Ngoy B, Mvingu K, Mulenga M. Comparative in vitro Sun Protection Factor (SPF) values of some herbal extracts found in Kinhasa by Ultraviolet Spectrophotometry. J Phy Chem Sci. 2015; 2(4):1-6.

Sayre RM, Agin PP, LeVee GJ, Marlowe E. A comparison of in vivo and in vitro testing of sunscreen formulas. Photochem Photobiol. 1979; 29(3):559-66.

Yadav M, Chatterji S, Gupta SK, Watal G. Preliminary phytochemical screening of six medicinal plants used in traditional medicine. Int J Pharm Pharm Sci. 2014;6(5):539-42.

Cohen PA, Ernst E. Safety of herbal supplements: a guide for cardiologists. Cardio Thera. 2010;28(4):246-53.

Bimakr M, Rahman RA, Taip FS, Ganjloo A, Salleh LM, Selamat J, Hamid A, Zaidul IS. Comparison of different extraction methods for the extraction of major bioactive flavonoid compounds from spearmint (Mentha spicata L.) leaves. Food Bio Proc. 2011;89(1):67-72.

Chaves JO, De Souza MC, Da Silva LC, Lachos-Perez D, Torres-Mayanga PC, Machado AP, Forster-Carneiro T, Vázquez-Espinosa M, González-de-Peredo AV, Barbero GF, Rostagno MA. Extraction of flavonoids from natural sources using modern techniques. Front Chem. 2020;8:1-25.

Ghazi S. Do the polyphenolic compounds from natural products can protect the skin from ultraviolet rays?. Results Chem. 2022;4:1-10.



How to Cite

Ali, Z., Kaushik, S., Singh, R., & Bhatt, B. (2023). Exploration of Phytochemical and Sun Protection Efficacy of Anthocephalus chinensis Leaves Extracts: http://www.doi.org/10.26538/tjnpr/v7i4.17. Tropical Journal of Natural Product Research (TJNPR), 7(4), 2773–2776. Retrieved from https://tjnpr.org/index.php/home/article/view/1885