An Overview of Pomegranate Peel: A Waste Treasure for Antiviral Activity


  • Wafaa M. Hikal Department of Biology, Faculty of Science, University of Tabuk, Tabuk, 71421, Saudi Arabia
  • Hussein A. H. Said-Al Ahl Medicinal and Aromatic Plants Research Department, Pharmaceutical and Drug Industries Research Institute, National Research Centre (NRC), 33 El–Behouth St., Dokki, Giza 12622, Egypt
  • Kirill G. Tkachenko V. L. Komarov Botanical Institute of the Russian Academy of Sciences, Saint Petersburg, Russia
  • Abeer A. Mahmoud Botany Department (Plant Physiology Section), Faculty of Agriculture, Cairo University, Gammaa St., Giza, 12613, Egypt
  • Amra Bratovcic Department of Physical Chemistry and Electrochemistry, Faculty of Technology, University of Tuzla, Tuzla, Bosnia and Herzegovina
  • Sanel Hodžić DVM (doctor of veterinary medicine), CEO at Veterinary laboratory Multi Lab doo Tuzla, Bosnia and Herzegovina 
  • Maria Atanassova Scientific Consulting, Chemical Engineering, UCTM, Sofia, Bulgaria


Human Virus, Pomegranate peel extract, Antiviral effect, Plant active components


Agricultural waste has always been a global problem that causes environmental pollution, and thanks to the efforts of scientists, this agricultural waste has become not a neglected product, but rather a source of many effective chemical compounds that have industrial, pharmaceutical and food applications. Viral disease therapy has attracted a great deal of scientific interest worldwide. Therefore, the pace of research is increasing for effective and safe treatment. The potential inhibitory activity of pomegranate peel extract polyphenols against virus for effective viral disease therapy has attracted a great deal of scientific interest. The aim of this review was to present an overview of the pomegranate peel effects on viruses such as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), Influenza virus, Norovirus, Adenovirus, Herpes simplex virus, Coronavirus disease (COVID-19). Pomegranate is consumed as fresh fruit and juice for its reported health benefits as antioxidant, antidiabetic, hypolipidemic, antibacterial, anti-inflammatory, antiviral, anticarcinogenic activities, and improves cardiovascular as well as oral health. The health benefits of pomegranate have been attributed to its wide range of phytochemicals, which are predominantly polyphenols, ellagitannins, anthocyanins, and other polyphenols. Instead of the pomegranate peel being a neglected product, it is considered as a promising antiviral agent which also offers other health benefits without side effects. 

Author Biography

Wafaa M. Hikal, Department of Biology, Faculty of Science, University of Tabuk, Tabuk, 71421, Saudi Arabia

Environmental Parasitology Laboratory, Water Pollution Research Department, Environment and Climate Change Institute, National Research Centre (NRC), 33 El–Behouth St., Dokki, Giza 12622, Egypt


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How to Cite

M. Hikal, W., A. H. Said-Al Ahl, H., G. Tkachenko, K., A. Mahmoud, A., Bratovcic, A., Hodžić, S., & Atanassova, M. (2022). An Overview of Pomegranate Peel: A Waste Treasure for Antiviral Activity: Tropical Journal of Natural Product Research (TJNPR), 6(1), 15–19. Retrieved from