Chemical Composition, Antioxidant and Antimicrobial Activities of Essential Oils Extracted from the Fresh and Dried Seeds of Lanxangia tsao-ko grown in Nghe An, Vietnam

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Hieu T. Tran
Nhan D. Le
Hang T.T. Tran
Thu-Hang T. Tran
Men T. Ngo
Vy T.H. Nguyen
Khoa D. Nguyen
Danh Vu
Chen V. Tran
Giang D. Le


Lanxangia tsao-ko has been used in traditional oriental medicine to treat malaria, abdominal pain, digestive disorders, and inflammation-related diseases. The aim of this study was to compare the volatile composition and evaluate the total phenolic content (TPC), antioxidant, and antimicrobial activities of L. tsao-ko fresh and dried seed essential oils (EOs) grown in Vietnam. The EOs of L.  tsao-ko seeds were analyzed by gas chromatography-mass spectrometry. The results showed thatthe major constituents of the seed essential oils were 1,8-cineole, α-citral, tetracyclo[,9)]decan-10-one, α-phellandrene, and β-citral. The TPC ranged from 1.47mg GAE/g EO in EOs of fresh seeds to 1.70 mg GAE/g EO in EOs of dried seeds. The EOs extracted from fresh and dried seeds could scavenge DPPH with IC50 values of 68.79 and 56.44 mg/mL, respectively. Moreover, the EOs were shown to be active against E. faecalis, S. aureus, cereus, E. coli, P. aeruginosa, S. .enterica, and C. albicans (with MIC = 32-128 µg/mL). The results generally indicated significant differences in chemical composition and bioactivities between EOs obtained from fresh and dried seeds. The findings of the study provide more information about the volatile profile and additional evidence of potential health-endorsing properties of L. tsao-ko EOs.

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Tran, H. T., Le, N. D., Tran, H. T., Tran, T.-H. T., Ngo, M. T., Nguyen, V. T., Nguyen, K. D., Vu, D., Tran, C. V., & Le, G. D. (2023). Chemical Composition, Antioxidant and Antimicrobial Activities of Essential Oils Extracted from the Fresh and Dried Seeds of Lanxangia tsao-ko grown in Nghe An, Vietnam: Tropical Journal of Natural Product Research (TJNPR), 7(2), 2426–2431. Retrieved from


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