Influence of Green Solvent Extraction on Phytochemicals, Potential Antidiabetic and In Vitro Anti-Inflammatory Activities of Pseuderanthemum palatiferum (Nees.) Radlk. Leaves
http://www.doi.org/10.26538/tjnpr/v7i1.16
Keywords:
Pseuderanthemum palatiferum, phenolics, antioxidant, glucosidase, antiinflammatoryAbstract
Pseuderanthemum palatiferum (Nees.) Radlk., belonging to the Acanthaceae family, is commonly cultivated in Vietnam and Thailand for food and medicinal uses. The aim of the study was to compare phenolic composition, antioxidant, potential anti-inflammatory and antidiabetic activities of different extracts obtained from ethanol, 80% ethanol and water. The use of these solvents significantly affected the extractability of phytochemical classes, phenolic contents and bioactivities in the extracts. The extract obtained from 80% ethanol contained the highest amount of phenolics (113.74 26.17 mg GAE/g). It also appeared to be more suitable for recovering phenolic constituents in P. palatiferum leaves. The extracts obtained from ethanol and 80% ethanol showed significantly higher antioxidant potential and inhibition of -glucosidase compared to water. Regarding inhibition of bovine albumin denaturation, no differences were observed for the extracts at the examined concentration. The research helps better understand phytochemical contents and potential health benefits of P. palatiferum, which could be used for development of new plant-derived agents for disease prevention and treatment.
References
Dieu HK, Loc CB, Yamasaki S, and Hirata Y. The ethnobotanical and botanical study on Pseuderanthemum palatiferum as a new medicinal plant in the Mekong Delta of Vietnam. Japan Agricultural Research Quarterly: JARQ. 2005; 39:191-196.
Khanh TC. The truth of a miraculous medicinal plant: Pseuderanthemum palatiferum. J Med Health. 1997; 101:10-11.
Jeszka-Skowron M, Zgoła-Grześkowiak A, and Frankowski R. Cistus incanus a promising herbal tea rich in bioactive compounds: LC–MS/MS determination of catechins, flavonols, phenolic acids and alkaloids—A comparison with Camellia sinensis, Rooibos and Hoan Ngoc herbal tea. J Food Compos Anal. 2018; 74:71-81.
Inchab K, Khonsung P, Chiranthanut N, Kunanusorn P, Panthong A, and Sireeratawong S. Evaluation of antiinflammatory, analgesic, and antipyretic activities of Pseuderanthemum palatiferum. Chiang Mai Univ J Nat Sci. 2019; 18:393-407.
Chayarop K, Temsiririrkkul R, Peungvicha P, Wongkrajang Y, Chuakul W, Amnuoypol S, and Ruangwises N. Antidiabetic effects and in vitro antioxidant activity of Pseuderanthemum palatiferum (Nees) Radlk. ex Lindau leaf aqueous extract. Pharm Soc Asia. 2011; 38:13-22.
Kongprasom U, Sukketsiri W, Chonpathompikunlert P, Sroyraya M, Sretrirutchai S, and Tanasawet S. Pseuderanthemum palatiferum (Nees) Radlk extract induces apoptosis via reactive oxygen species-mediated mitochondria-dependent pathway in A549 human lung cancer cells. Trop J Pharm Res. 2019; 18:287-294.
Komonrit P and Banjerdpongchai R. Effect of Pseuderanthemum palatiferum (Nees) Radlk fresh leaf ethanolic extract on human breast cancer MDA-MB-231 regulated cell death. Tumor Biol. 2018; 40:1010428318800182.
Mai HDT, Minh HNT, Pham VC, and Bui KN. Lignans and other constituents from the roots of the Vietnamese medicinal plant Pseuderanthemum palatiferum. Planta Med. 2011; 77:951-954.
Lichtenthaler HK and Wellburn AR, Determinations of total carotenoids and chlorophylls a and b of leaf extracts in different solvents. 1983, Portland Press Ltd.
Vu D. Assessing the Differences in Phenolics, Antioxidant and Anti-Tyrosinase Activities of Spent Coffee Ground Fractions. Trop J Nat Prod Res. 2022; 6(4):558-562.
Aly AA, Ali HGM, and Eliwa NER. Phytochemical screening, anthocyanins and antimicrobial activities in some berries fruits. J Food Meas Charact. 2019; 13:911-920.
Vu DC, Vu QT, Huynh L, Lin C-H, Alvarez S, Vo XT, and Nguyen THD. z valuation of fatty acids, phenolics and bioactivities of spent coffee grounds prepared from Vietnamese coffee. Int J Food Prop. 2021; 24:1548-1558.
Xiao Y, Xing G, Rui X, Li W, Chen X, Jiang M, and Dong M. Enhancement of the antioxidant capacity of chickpeas by solid state fermentation with Cordyceps militaris SN-18. J Funct Foods. 2014; 10:210-222.
Zengin G, Sinan KI, Mahomoodally MF, Angeloni S, Mustafa AM, Vittori S, Maggi F, and Caprioli G. Chemical composition, antioxidant and enzyme inhibitory properties of different extracts obtained from spent coffee ground and coffee silverskin. Foods. 2020; 9(6):713.
Uttra AM, Shahzad M, Shabbir A, Jahan S, Bukhari IA, and Assiri AM. Ribes orientale: A novel therapeutic approach targeting rheumatoid arthritis with reference to proinflammatory cytokines, inflammatory enzymes and antiinflammatory cytokines. J Ethnopharmacol. 2019; 237:92- 107.
Chayarop K, Peungvicha P, Wongkrajang Y, Chuakul W, Amnuoypol S, and Temsiririrkkul R. Pharmacognostic and phytochemical investigations of Pseuderanthemum palatiferum (Nees) Radlk. ex Lindau leaves. Pharmacogn J. 2011; 3:18-23.
Phan MG, Ha VB, and Phan TS. Phytochemical study on Pseuderanthemum palatiferum (Nees) Radlk., Acanthaceae. J Chem. 2003; 41:115-118.
Sittisart P, Chitsomboon B, and Kaminski NE. Pseuderanthemum palatiferum leaf extract inhibits the proinflammatory cytokines, TNF-α and IL-6 expression in LPS-activated macrophages. Food Chem Toxicol. 2016; 97:11-22.
Pulbutr P, Nualkaew S, Rattanakiat S, Cushnie B, and Jaruchotikamol A. Inhibitory actions of Pseuderanthemum palatiferum (Nees) Radlk. leaf ethanolic extract and its phytochemicals against carbohydrate-digesting enzymes. Asian Pac J Trop Biomed. 2016; 6:93-99.
Ulbricht C, Bramwell R, Catapang M, Giese N, Isaac R, Le T-D, Montalbano J, Tanguay-Colucci S, Trelour NJ, and Weissner W. An evidence-based systematic review of chlorophyll by the Natural Standard Research Collaboration. J Diet Suppl. 2014; 11:198-239.
Quang-Vinh N and Jong-Bang E. Antioxidant activity of solvent extracts from Vietnamese medicinal plants. J Med Plant Res. 2011; 5:2798-2811.
Sittisart P and Chitsomboon B. Intracellular ROS scavenging activity and downregulation of inflammatory mediators in RAW264. 7 macrophage by fresh leaf extracts of Pseuderanthemum palatiferum. Evid.-Based Complementary Altern. Med. 2014; 2014:1-11.
Nualkaew S, Padee P, and Talubmook C. Hypoglycemic activity in diabetic rats of stigmasterol and sitosterol-3-O-- D-glucopyranoside isolated from Pseuderanthemum palatiferum (Nees) Radlk. leaf extract. J Med Plant Res. 2015; 9:629-635.
Ruiz-Ruiz JC, Matus-Basto AJ, Acereto-Escoffié P, and Segura-Campos MR. Antioxidant and anti-inflammatory activities of phenolic compounds isolated from Melipona beecheii honey. Food Agric Immunol. 2017; 28:1424-1437.
Williams LAD, O'Connar A, Latore L, Dennis O, Ringer S, Whittaker JA, Conrad J, Vogler B, Rosner H, and Kraus W. The in vitro anti-denaturation effects induced by natural products and non-steroidal compounds in heat treated (immunogenic) bovine serum albumin is proposed as a screening assay for the detection of anti-inflammatory compounds, without the use of animals, in the early stages of the drug discovery process. West Indian Medical Journal. 2008; 57:327–331.
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