Development of Topical Formulations with Antibacterial Efficacy from Peel Extract of Mangifera indica: Emulsions and Micro-emulsions http://www.doi.org/10.26538/tjnpr/v6i12.19

Main Article Content

Pornsak Sriamornsak
Arzu Polat
Bighan Torabi
Wantanwa Krongrawa
Anne Krüger-Genge
Joachim Storsberg
Tassilo Seidler
Mont Kumpugdee-Vollrath

Abstract

Because some pathogenic bacteria are becoming more resistant to known antibiotics, more research into the development of new antibacterial agents is required. The main study objective was to develop several formulations containing peel extract of Mangifera indica (mango) and evaluate their antibacterial efficacy. The macerating extraction process was used to produce the mango peel extract. Cytotoxicity of the mango peel extract was also evaluated. The emulsions and microemulsions were prepared and assessed based on their appearance, phase separation, consistency, viscosity, and conductivity. The formulations were then evaluated for antibacterial and growth inhibitory effects against gram-negative (Escherichia coli) and gram-positive (Staphylococcus aureus) bacteria. The findings revealed that no cytotoxic effects on skin keratinocyte cells were identified. Most formulations were physico-chemically acceptable. Only S. aureus bacteria were inhibited by emulsions and microemulsions containing mango peel extract. 

Article Details

How to Cite
Sriamornsak, P., Polat, A., Torabi, B., Krongrawa, W., Krüger-Genge, A., Storsberg, J., Seidler, T., & Kumpugdee-Vollrath, M. (2022). Development of Topical Formulations with Antibacterial Efficacy from Peel Extract of Mangifera indica: Emulsions and Micro-emulsions: http://www.doi.org/10.26538/tjnpr/v6i12.19. Tropical Journal of Natural Product Research (TJNPR), 6(12), 2014–2019. Retrieved from https://tjnpr.org/index.php/home/article/view/1408
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Author Biography

Pornsak Sriamornsak, Faculty of Pharmacy, Silpakorn University, Nakhon Pathom 73000, Thailand

Academy of Science, The Royal Society of Thailand, Bangkok 10300, Thailand

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