Phytochemical Profile and in vitro Sun-Protective Activity of Polyalthia longifolia (Sonn.) Thwaites Bark Extracts doi.org/10.26538/tjnpr/v6i8.1
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Abstract
Sunscreen formulations are required to protect the skin from damaging ultraviolet radiation, which causes irritation, erythema (sunburn), generalized or localized hyperpigmentation (tanning), skin malignancies, immunosuppression, and inflammation. Efficacious, high-quality products are in high demand currently. There are some sunscreens with broad spectrum UV protection that are inexpensive, safe, and herbal. The present study was conducted to investigate the phytochemical profile and sun-protective properties of Polyalthia longifolia (Sonn.) Thwaites extracts. The bark of P. longifolia was extracted with water, ethanol, and petroleum ether by the cold maceration method. A preliminary phytochemical screening on the P. longifolia bark extracts was conducted. The in vitro sun-protective activity of the different P. longifolia extracts was assessed by determining the sun protection factor (SPF) using the UV spectroscopic technique. The results of the phytochemical screening revealed the presence of flavonoids, phenols, and tannins in all the P. longifolia bark extracts. The SPF values of the different extracts were observed to be 5.24±0.002, 1.07±0.009, and 1.01±0.012 for the ethanolic, petroleum ether, and water extracts, respectively. The findings of this study suggest that the aqueous, ethanol, and petroleum ether extracts of P. longifolia bark could be used to make photoprotective formulations that have additive or synergistic effects in a variety of combinations and quantities.
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