Aphrodisiac Properties and Reproductive Hormones Concentrations of Ethanol Leaf Extract of Eremomastax speciosa in Male Wistar Rats http://www.doi.org/10.26538/tjnpr/v6i11.25
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Abstract
The effects of Eremomastax speciosa leaf extract on reproductive activities was evaluated; antioxidant activities and the hytochemistry of Eremomastax speciosa were assayed using standard methods. Thirty-five matured male Wistar rats were used for the experiment and they were divided into five groups of seven rats each; groups 1 and 2 were the positive and normal controls respectively and were given Manix capsule and distilled water respectively. Groups 3, 4 and 5 were administered the ethanol extract at the doses of 400 mg/kg, 200 mg/kg, and 100 mg/kg respectively. Twelve matured female rats were used for the aphrodisiac assessment. The phytochemical screening showed the presence of Alkaloids, Tannins, Saponins, Terpenes and Flavonoids and the leaves showed a significant free scavenging activity with an IC50 value of 90 μg/ml. The result showed a dose-dependent significant (P<0.05) increase in Testosterone levels and also an increase in Follicle Stimulating Hormone (FSH) and Luteinizing Hormone (LH) which was not significant when compared with the normal control. The result also showed a dose-dependent significant increase in the mount, intromission and ejaculatory frequencies while decreasing their latencies when compared with the normal control. In conclusion, the ethanol leaf extract of Eremomastax speciosa possesses aphrodisiac potentials and could boost testosterone level which could enhance reproductive indices.
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