Pretreatment with Oil Palm Leaf Extracts Confers Protection against Crude Oil Adulterated Food (COAF) doi.org/10.26538/tjnpr/v4i9.24
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Abstract
The medicinal importance of oil palm leaf is attracting attention. The present study explored the role of various solvent extracts of the oil palm leaf in conferring protection in rats consuming crude oil adulterated food. The study comprised the use of forty (40) albino rats assigned randomly to eight (8) groups with five in each group. Rats in the control group (Group 1) served as control and were neither exposed to crude oil contaminated diet nor pre-treated with oil palm leaf extracts. Rats in group 2 were initially maintained on a normal diet. Rats in group 3-7 were pre-treated with 250 mg/kg bodyweight of various solvent extracts (aqueous, methanol, ethanol, acetone, and petroleum ether), while rats in group 8 were pre-treated with 250 mg/kg bodyweight of a blended mixture of (aqueous, methanol, ethanol, acetone, and petroleum ether) extracts of palm leaves. Each treatment was for four weeks. Thereafter, the rats in groups 2-8
were exposed to crude oil contaminated diets (4 mL per 100 g of feed) for another four weeks. The body weight of the rats and biochemical indices: hematological, liver function indices and oxidative stress indicators were determined using standard biochemical protocols. The results showed crude oil-mediated derangement of hematological parameters, liver function indices in addition to increased tissue malondialdehyde and depletion of tissue antioxidants. Pretreatment with oil palm leave extracts, however, reduced the trend in these metabolic derangements. Thus, pretreatment of animals with oil palm leaf extract confers protection against crude oil poisoning.
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Shirneshan G, Bakhtiari AR, Memariani M. Identifying the source of petroleum pollution in sediment cores of southwest of the Caspian Sea using chemical fingerprinting of aliphatic and alicyclic hydrocarbons. Marine Pollut Bull. 2017; 115(1-2):383- 390.
Medubari BN and Elijah IO. The effects of crude oil contaminated forage on breeding behavior and reproductive performance of female rabbits. Int J Plant Anim Environ Sci. 2014; 6:462–472.
Eneh OC. A Review on Petroleum: Source, uses, processing, products and the environment. J Appl Sci. 2011; 11:2084-2091.
Nikanorov AM, Stradomskaya AG. Identification of petroleum pollution sources of water bodies and streams. Water Resour. 2009; 36(2):163–169.
USDE Environmental benefits of advanced oil and gas exploration and production technology. U. S. Department of energy. Office of fossil energy. 1993; 168 pp
Ogara AL, Joshua PE, Omeje KO, Onwurah IN. Effects of ingested crude oil contaminated diets on antioxidant enzyme and lipid profile in Wistar albino rat. J Appl Sci Environ Manage. 2016; 20(4):927-932.
Achuba FI and Nwokogba CC. Effects of honey supplementation on hydrocarbon-induced kidney and liver damage in Wistar albino rats. Biokemistri. 2015: 27(1):50-55.
Achuba FI and Ogwumu MD. Possible protective role of palm oil and beef liver on the kidney and liver of Wistar albino rats fed diesel-contaminated diet. Biokemistri. 2014a; 26(4):124–129.
Kori-Siakpere O. Petroleum-induced alterations in the African catfish, Clarias gariepinus (Teugels, 1984) I: Haematology. Nig J Sci Environ. 1998; 1:49-55.
Achuba FI and Osakwe SA. Petroleum-induced free radical toxicity in Africa catfish (Clarias gariepinus) Fish Physiol. Biochem. 2003; 29(2):97-103.
Uboh FE, Ebong PE, Akpan HD, Usoh IF. Hepatoprotective effect of vitamins C and E against gasoline vapor-induced liver injury in male rats. Turkish J Biol. 2012; 36:217-223.
Patrick-Iwuanyanwu KC, Onyemaenu CC, Wegwu MO, Ayalogu EO. Hapatotoxic and nephrotoxic effect of kerosene and gasoline-contaminated diet in the Wistar albino Rats. Res Environ Toxicol. 2011; 5:49–57.
Ujowundu CO, Kalu FN, Nwaogu LA, Ezeji EU, Igwe KO. Management of changes in liver chemistry in male rats acutely exposed to crude petroleum oil. J Appl Pharm Sci. 2012; 2(06):116-120.
Achuba FI. Modulation of crude oil induced alteration of oxidative stress indices in rat by red palm oil. J Appl Sci Environ Manage. 2018a; 22(6):929-932.
Nisar B, Sultan A, Rbab SL. Comparison of medicinally important natural products versus synthetic drugs-A short commentary. Nat Prod Chem Res. 2017; 6:308.
Karimi A, Majlesi M, Rafieian-Kopaei M. Herbal versus synthetic drugs; beliefs and facts. J Nephropharmacol. 2015; 4(1):27–30.
Stratton CF, Newman DJ, Tan DS. Cheminformatic comparison of approved drugs from natural product versus synthetic origins.Bioorganic Med Chem Lett. 2015; 25(21):4802–4807.
Achuba FI. Role of bitter leaf (Vernonia amygdalina) extract in prevention of renal toxicity induced by crude petroleum contaminated diets in rats. Int J Vet Sci Med. 2018b; 6(2):172- 177.
Achuba FI. Evaluation of the protective effects of bitter leaf (Vernonia amygdalina) on haematological indices of rats fed with crude oil treated diet. J Appl Environ Manage. 2018c; 22(4):489 – 492.
Achuba FI. Bitter leaf (Vernonia amygdalina Del) extract potentiates testicular metabolic stress induced by petroleumtainted diets in rats. Nig J Pharm Appl Sci Res. 2019; 8(1):44-51.
Okpoghono J, Achuba FI, George BO. Protective effects of Monodora myristica extracts on crude petroleum oilcontaminated catfish (Clarias gariepinus) diet in rats. Int J Vet Sci Med. 2018a; 6:117–122.
Okpoghono J, George BO, Achuba FI. Assessment of antioxidant indices after incorporating crude oil contaminated catfish and African nutmeg (Monodora myristica) extracts into rat diet. J Appl Sci Environ Manage. 2018b; 22(2):197 – 202.
Okpoghono J, Achuba FI, George BO. Influence of Monodora myristica extracts on lipid profile of rats fed crude petroleum oil contaminated catfish diet. Sokoto J Med Lab Sci. 2018c; 3(1):19- 27.
Achuba FI, Ubogu LA, Ekute BO. Moringa oleifera treatment prevents crude oil tainted diet imposed toxicity in rats. Sokoto J Med Lab Sci. 2018; 3(3):99 – 105.
Achuba FI. Effect of Moringa oleifera on crude oil mediated haematotoxicity in Wistar albino rats. Nig J Pure Appl Sci. 2018d; 31(2):3192-3196.
Achuba FI. Protective Influence of Elaesis guineensis leaf in diet on petroleum-mediated kidney damage in rat. Nig J Pharm Appl
Sci Res. 2018e; 7(2):33-38.
Achuba FI. Powdered Oil Palm (Elaesis guineensis Jacq) leaf as remedy for hydrocarbon induced liver damage in rats. Nig J Pharm Appl Sci Res. 2018f; 7(3):89-95.
Yin NS, Abdullah S, Phin CK. Phytochemical constituents from leaves of Elaeis guineensis and their antioxidant and antimicrobial activities. Int J Pharm Pharm Sci. 2013; 5:137-140.
Mohamed S. Oil palm leaf: A new functional food ingredient for health and disease prevention. J Food Proc Technol. 2014; 5:300.
George BO, Osioma E, Okpoghono J, Aina OO. Changes in liver and serum transaminases and alkaline phosphatase enzyme activities in Plasmodium berghei infected mice treated with aqueous extract of Aframomum sceptrum. Afr J Biochem Res.2011; 5(9):277-281.
Achuba FI and Obaremi C. Effects of selenium fortified diet on inflammatory markers in Wistar albino rats exposed to crude oil. Nig J Pharm Biomed Res. 2018; 3(3):209-216.
Thrall MA and Weiser MG. Haematology. In: Hendrix C. M. (Ed.) Laboratory Procedures for Veterinary Technicians,4th Edition, Mosby Incorporated, Missouri, USA. 2002. 29 – 74 p.
Tietz NW. Fundamentals of clinical chemistry, W B Saunders Co. Philadelphia, 1976. 723 p.
Reitman S and Frankel SA. A colomentric method for determination of serum glutamic oxaloacetic acid and glutamic pyruvic transminases. Am J Clin Pathol. 1957; 28(1):56-63.
Kaplan MM and Righetti A. Assay for alkaline phosphatase. The J Clin Invest. 1955; 34:126-127.
Droumas BT, Waston WA, Biggs HG. Albumin standard and the measurement of serum albumin with bromocresol green. Clinica Chimica Acta. 1971; 31:87-96.
Gutteridge JMC and Wilkins C. Copper dependent hydroxyl radical damage to ascorbic acid. Formation of a thiobarbituric acid reactive products. FEBS Lett.1982; 137:327-340.
Ellman GL. Tissue sulfhydryl groups. Arch Biochem Biophy. 1959; 82:70-77.
Misra HP and Fridovich I. The role of superoxide anion in the autooxidation of epinephrine and a sample assay for superoxide dismutase. J Biol Chem. 1972; 247:3170-3175.
Kaplan A, Dembiec D, Cohen G, Marcus J. Measurement of catalase activity in tissue extracts. Analy Biochem. 1972; 34:30- 38.
Achuba FI and Ogwumu MD. Effect of palm oil and beef liver on diesel-induced haematotoxicity in wistar albino rats. Biokemistri. 2014b; 26(4):120–123.
Sunmonu TO and Oloyede OB. Biochemical assessment of the effects of crude oil contaminated catfish (Clarias gariepinus) on the hepatocytes and performance of rat. Afr J Biochem Res. 2007; 1(5):083-089.
Ugwu LLC, Ude EF, Nwamba HO, Chima IN. Effect of crude oil and some petroleum products on Clarias gariepinus Fingerlings (Catfish: Claridae) Continent J Fisher Aquat Sci. 2011; 5(1):24 – 30.
Onakurhefe P, Achuba FI, George BO. Phytochemical analysis and chemical characterization of extracts and blended mixture of palm oil leaf. Trop J Nat Prod Res. 2019; 3(9):282-297.
Onakurhefe P, Achuba FI, George BO, Okpoghono J Effect of Elaeis guineensis (Jacq) leaf extracts on crude oil-induced genotoxicity in Wistar albino rats. Sci Afr. 2020; 7:e00280.
Falcone FH, Haas H, Gibbs BF. The human basophil: a new appreciation of its role in immune responses. Blood 2000; 96(13):4028–4038.
Alberts B, Johnson A, Lewis M, Raff M, Roberts K, Walter P. Leukocyte also known as macrophages functions and percentage breakdown. Molecular Biology of the Cell (4th ed.). New York: Garland Science. 2002. 712 p.
Saladin K. Anatomy and Physiology: the Unit of Form and Function. (6 ed.). New York: McGraw Hill. 2012. 417 p.
Ichipi-Ifukor PC, Asagba SO, Nwose C. Potentiating role of palm oil (Elaeis guineensis) and its extracts in cadmium-induced alteration of aminotransferases in albino rats. Thai J Pharm Sci. 2019; 43(1):36-48.
Kweki GR, Ichipi-Ifukor PC, Asagba SO. High caffeinecontaining energy drink- induced metabolic stress in rats. Sokoto J Med Lab Sci. 2018; 3(3):86-93.
Rahman MF, Siddiqui MK, Jamil K. Acid and alkaline phosphatase activities in a novel phosporothionate (RPR 11) treated male and female rats; evidence of dose and time dependent response. Drug Chem Toxicol. 2000; 23:497-509.
Rezg R, Mornagui B, Kamoun A. Effect of sub-chronic exposure to malathion on metabolic parameters in rat. Comptes Rendus Biologies. 2007; 330:143-147.