Adicardin and Other Coumarins from Breonadia salicina (Vahl) Hepper

doi.org/10.26538/tjnpr/v3i9.3

Authors

  • Barnabas J. Nvau Department of Chemistry, Plateau State University, Bokkos, Nigeria.
  • Bawazeer Sami College of Pharmacy, Umm Al-qura University, Makkah, Saudi Arabia,
  • Olugbenga S. Ajibade Department of Chemical Sciences, Redeemer’s University, Ede, Osun State, Nigeria
  • Irvine A. Gray Strathclyde Institute of Pharmacy and Biomedical Sciences, University of Strathclyde, 161 Cathedral Street, G4 0RE, Glasgow UK
  • John. O. Igoli Department of Chemistry, University of Agriculture, Makurdi, Nigeria.

Keywords:

Terpenoids,, Coumarins,, Medicinal plant,, Breonadia salicina, Adicardin.

Abstract

Breonadia salicina is an ethnomedicinal plant used in North Central Nigeria to treat sleeping sickness and respiratory diseases. The stem bark of the plant was extracted with methanol and the extract partitioned between dichloromethane and water. The dichloromethane soluble portion was subjected to column chromatography which resulted in the isolation of 7-(β-D- apiofuranosyl (1-6)-β-D-glucopyranosyl) umbelliferone, α-amyrin, stigmasterol, 7- hydroxycoumarin and 6- hydroxy-7-methoxy coumarin. The structures of these compounds were elucidated based on NMR spectral analysis. This is the first report of these compounds from the plant.

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Published

2019-09-01

How to Cite

J. Nvau, B., Sami, B., S. Ajibade, O., A. Gray, I., & O. Igoli, J. (2019). Adicardin and Other Coumarins from Breonadia salicina (Vahl) Hepper: doi.org/10.26538/tjnpr/v3i9.3. Tropical Journal of Natural Product Research (TJNPR), 3(9), 298–301. Retrieved from https://tjnpr.org/index.php/home/article/view/1000

Issue

Vol. 3 No. 9 (2019): Tropical Journal of Natural Product Research

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