The Potential of Strawberry (Fragaria ananassa) Fruit Extract in the Treatment of Hyperpigmentation: A Mini Review

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Published: Mar 28, 2025
DOI: https://doi.org/10.26538/tjnpr/v9i3.02
Keywords:
Strawberry, Fragaria ananassa, Fruit Extract, Hyperpigmentation

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Olivia J. Purnomo
Master Program in Biomedical Science, Anti-Aging Medicine, Faculty of Medicine, Udayana University, Jl. PB Sudirman Denpasar, Bali 80234, Indonesia
Dewa A. A. S. Laksemi
Department of Parasitology, Faculty of Medicine, Udayana University, Jl. PB Sudirman Denpasar, Bali 80234, Indonesia
I. G. N. Darmaputra
Department of Dermatology and Venerology, Faculty of Medicine, Udayana University/Sanglah General Hospital, Denpasar, Indonesia

Abstract

Hyperpigmentation is a skin condition that significantly affects aesthetics. It is caused by an increase in melanogenesis or uneven distribution of melanin, resulting in the darkening of skin colour. The gold standard for treating hyperpigmentation is the use of hydroquinone, but this substance has many adverse effects on the body. Therefore, assessing the potential for the use of natural extracts, such as strawberries, for the treatment of hyperpigmentation is essential. The aim of this study was to identify the active compounds in strawberry extract, explain its mechanism of action in the treatment of hyperpigmentation, and evaluate its feasibility as a natural alternative in skincare formulations, providing a safe, effective, and sustainable solution for hyperpigmented skin. A literature search was conducted, and data were obtained from various databases such as PubMed, Google Scholar, NCBI, and ResearchGate. The results of the study indicated that ethanol extract of strawberry fruit can improve skin colour, skin hydration, and firmness, while also reducing the visibility of hyperpigmentation. The ethanol extract of strawberry fruit has the potential to act as a sunscreen and tyrosinase inhibitor, effectively inhibiting melanin formation, making it a promising treatment for hyperpigmentation.

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How to Cite
Purnomo, O. J., Laksemi, D. A. A. S., & Darmaputra, I. G. N. (2025). The Potential of Strawberry (Fragaria ananassa) Fruit Extract in the Treatment of Hyperpigmentation: A Mini Review. Tropical Journal of Natural Product Research (TJNPR), 9(3), 896-903. https://doi.org/10.26538/tjnpr/v9i3.02
Issue
Vol. 9 No. 3 (2025): Tropical Journal of Natural Product Research (TJNPR)
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Articles
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This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

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