Herbal Medicine as an Alternative Management for Prediabetes: A Review
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Abstract
Prediabetes refers to a state of dysglycaemia, a transitional phase between normoglycaemia and diabetes. Early identification of prediabetes, followed by appropriate management and treatment, is vital to prevent its progression to diabetes, which is an incurable condition. A widely available and rapidly developing therapy option is herbal medicine. This systematic review examines various herbal medications that can be utilised as therapy for prediabetic patients. Literature was obtained through searches in online journal databases such as Pubmed and Cochrane according to the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) stages. The keywords are herbal or "herbal medicine", "traditional medicine" or "alternative medicine", and prediabetes or "impaired glucose tolerance" or "impaired fasting glucose". A total of 7 journals were included in this study. Various plants utilised as herbal medicine have been researched and published for their efficacy and safety as prediabetes therapy such as Panax ginseng Meyer (enhancing β cell function and increasing insulin sensitivity), Tang-Yi-Ping (improving pancreatic β-cell proliferation and protecting β-cell number and function), Jinlida granules (producing a significant reduction in blood glucose levels 2 hours postprandial and HbA1c levels), Allium hookeri (reducing the inflammatory response to hyperglycemia), Nisha-Amalaki capsules (having insulin sensitising effects), Trigonella foenum-graceum (stimulating pancreatic beta cells), and Moringa oleifera nanoparticles (MoNP) (regulating inflammatory cytokines; increasing the activity of glucokinase enzymes and pancreatic β-cells, lowering insulin resistance, and activating GLUT-4). In conclusion, herbal medicine is known to provide promising results for the treatment and prevention of prediabetes.
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