Green Synthesis, Optimization and Characterization of Carrot Extract Silver Nanoparticles
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Abstract
Silver nanoparticles (AgNPs) are currently being used in the field of nanomedicine. Carrots are plants with phytochemicals that act as reducing and capping agents for nanoparticles. The use of plant extracts is considered a safe, non-toxic, and effective therapeutic option for various diseases. The aim of this study was to synthesis, optimize, and characterize silver nanoparticles using carrot extract. The green synthesis of carrot extract AgNPs was carried out by mixing ethanol extract of carrot with silver nitrate (AgNO3) at concentrations ranging from 1 to 3 mM and pH 6 - 8. Carrot extract silver nanoparticles (CE-AgNPs) was characterized using UV-Vis spectrophotometry, particle size analysis (PSA), Field Emission Scanning Electron Microscopy (FE-SEM), and X-ray diffractometry (XRD). The results showed that the optimal synthesis of carrot extract silver nanoparticles is done using AgNO3 at 1 mM concentration, and pH 7 which produced the smallest particle size. FE-SEM indicated the formation of spherical silver nanoparticles. XRD analysis indicated that the nanoparticles contain silver components. In conclusion, the conditions for carrot extract silver nanoparticles production can affect the particle size and morphology of the nanoparticles.
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Andal P, Tamilselvy S, Indra Priyatharesini P. Green synthesis of silver nanoparticles from carrot. Res J Pharm Technol. 2018; 11(7):2757–2760.
Liaqat N, Jahan N, Khalil-ur-Rahman, Anwar T, Qureshi H. Green synthesized silver nanoparticles: Optimization, characterization, antimicrobial activity, and cytotoxicity study by hemolysis assay. Front Chem. 2022; 10:1–13.
Fareed N, Nisa S, Bibi Y, Fareed A, Ahmed W, Sabir M, Alam S, Sajjad A, Kumar S, Hussain M, Syed A, Bahkali AH, Elgorban AM, Qayyum A. Green synthesized silver nanoparticles using carrot extract exhibited strong antibacterial activity against multidrug resistant bacteria. J King Saud Univ - Sci. 2023; 35(2):1-10.
Savvidou MG, Kontari E, Kalantzi S, Mamma D. Green Synthesis of Silver Nanoparticles Using the Cell-Free Supernatant of Haematococcus pluvialis Culture. Materials (Basel). 2024; 17(1):1-23.
Krithiga N, Rajalakshmi A, Jayachitra A. Green Synthesis of Silver Nanoparticles Using Leaf Extracts of Clitoria ternatea and Solanum nigrum and Study of Its Antibacterial Effect against Common Nosocomial Pathogens. J Nanosci. 2015; 2015:1–8.
Iravani S and Zolfaghari B. Green synthesis of silver nanoparticles using Pinus eldarica bark extract. Biomed Res Int. 2013;2013:1–5.
Noga M, Milan J, Frydrych A, Jurowski K. Toxicological Aspects, Safety Assessment, and Green Toxicology of Silver Nanoparticles (AgNPs)—Critical Review: State of the Art. Int J Mol Sci. 2023; 24(5133):1–27.
Zia M, Gul S, Akhtar J, Ul Haq I, Abbasi BH, Hussain A, Naz S, Chaudhary MF. Green synthesis of silver nanoparticles from grape and tomato juices and evaluation of biological activities. IET Nanobiotechnol. 2017; 11(2):193–199.
Ali IAM, Ahmed A Ben, Al-Ahmed HI. Green synthesis and characterization of silver nanoparticles for reducing the damage to sperm parameters in diabetic compared to metformin. Sci Rep. 2023; 13(1):1–15.
Pandian SRK, Kunjiappan S, Ravishankar V, Sundarapandian V. Synthesis of quercetin-functionalized silver nanoparticles by rapid one-pot approach. Biotechnologia. 2021; 102(1):75–84.
Fagbemi KO, Thonda OA, Daramola OO, Oyewole T, Adeduro OO, Samuel A, Popoola D, Aina DA. Antibacterial Activity of Silver Nanoparticles Synthesized Using Vitex grandifolia Against Multidrug-Resistant (MDR) Pathogens. Trop J Nat Prod Res. 2024; 8(8):8068–8074.
Ahmad T, Cawood M, Iqbal Q, Arino A, Batool A, Tariq RMS, Azam M, Akhtar S. Phytochemicals in Daucus carota and Their Health Benefits — Review Article. Foods. 2019; 8(9):424:1-22.
Soleti R, Coué M, Trenteseaux C, Hilairet G, Fizanne L, Kasbi-Chadli F, Mallegol P, Chaigneau J, Boursier J, Krempf M, Geoffriau E, Andriantsitohaina R, Ouguerram K. Carrot supplementation improves blood pressure and reduces aortic root lesions in an atherosclerosis-prone genetic mouse model. Nutrients. 2021; 13(4):1–14.
Sarfaraz S, Farooq N, Ashraf N, Aslam A, Sarwar G. Non Pharmacological Use of Daucus Carota Juice (Carrot Juice) as Dietary Intervention in Reducing Hypertension. Enz Eng. 2016; 5(2):1-5.
Abbasian F, Alavi MS, Roohbakhsh A. Dietary carotenoids to improve hypertension. Heliyon. 2023; 9(9):1-12.
Marliyati SA, Sulaeman A, Rahayu MP. Application of Carrot Powder as a Natural Source of Β-Carotene in Instant Noodle Products. J Gizi dan Pangan. 2016; 7(2):127-134.
Umadevi M, Shalini S, Bindhu MR. Synthesis of silver nanoparticle using D. carota extract. Adv Nat Sci Nanosci Nanotechnol. 2012; 3(2):1-8.
Hartati R, Fidrianny I, Fitria A. Characterization and Phytochemical Screening of Carrot Simplex and Review of Chemical Content and Pharmacological Activity of Carrot (Daucus Carota L.). Acta Pharm Indones. 2023; 48(2):12–25.
Umair M, Jabbar S, Nasiru MM, Lu Z, Zhang J, Abid M, Murtaza MA, Kieliszek M, Zhou L. Ultrasound-Assisted Extraction of Carotenoids from Carrot Pomace and Their Optimization through Response Surface Methodology. Molecules. 2021; 26(22):6763:1-16.
Yaseen B, Gangwar C, Kumar I, Sarkar J, Naik RM. Detailed Kinetic and Mechanistic Study for the Preparation of Silver Nanoparticles by a Chemical Reduction Method in the Presence of a Neuroleptic Agent (Gabapentin) at an Alkaline pH and its Characterization. ACS Omega. 2022; 7(7):5739–5750.
Husain S, Afreen S, Hemlata, Yasin D, Afzal B, Fatma T. Cyanobacteria as a bioreactor for synthesis of silver nanoparticles-an effect of different reaction conditions on the size of nanoparticles and their dye decolorization ability. J Microbiol Methods. 2019; 162:77–82.
Lestari TP, Tahlib FA, Sukweenadhi J, Kartini, Avanti C. Physical Characteristic and Antibacterial Activity of Silver Nanoparticles from Green Synthesis Using Ethanol Extracts of Phaleria macrocarpa (Scheff.) Boerl Leaves. Maj Obat Tradis. 2019; 24(1):16–21.
Savitri ES, Auliyah HN, Muchtaromah B. Characterisation, Metabolite Profile, and Antioxidant Activity of Silver Nanoparticles Synthesised Using the Algae Palmaria palmata. Trop J Pharm Res. 2024; 8:7698–7703.
Hanutami BNP and Budiman A. Article Review: Use of Nanotechnology in Herbal Medicine Formulation. Farmaka. 2017; 15(2):29–41.
Rahman A, Rehman G, Shah N, Hamayun M, Ali S, Ali A, Shah SK, Khan W, Shah MI, Alrefaei AF. Biosynthesis and Characterization of Silver Nanoparticles Using Tribulus terrestris Seeds: Revealed Promising Antidiabetic Potentials. Molecules. 2023; 28(10):1-16.
Armendariz V, Herrera I, Peralta-Videa JR, Jose-Yacaman M, Troiani H, Santiago P, Gardea-torresdey JL. Size controlled gold nanoparticle formation by Avena sativa biomass: Use of plants in nanobiotechnology. J Nanoparticle Res. 2004; 6(4):377–382.
Wang Y, Wei S. Green Fabrication of Bioactive Silver Nanoparticles Using Mentha pulegium Extract under Alkaline: An Enhanced Anticancer Activity. ACS Omega. 2022; 7(1):1494–504.
Halilu EM, Ngweh VA, Airemwen CO. Green Synthesis of Silver Nanoparticles from Parinari curatellifolia Methanol Stem Bark Extract and Evaluation of Antioxidant and Antimicrobial Activities. Trop J Nat Prod Res. 2023; 7(3):2498–505.