Extract and Fixed Oil of Moroccan Lavandula dentata Aerial Parts as Potential Antioxidants
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Abstract
Aromatic and medicinal plants constitute a vast source of bioactive compounds, with remarkable
chemical diversity. The aim of the present study is to investigate the antioxidant activity of
extracts and fixed oils of Lavandula dentata L. aerial parts. Dried powdered aerial parts of
Lavandula dentata was extracted with methanol by refluxing. Different solvent fractions of
aqueous methanol extract of L. dentata aerial part were prepared by successive extraction in
chloroform, ethyl acetate, and n-butanol in order of increasing polarity. Fixed oil of L. dentata
aerial parts was obtained by maceration in chloroform at room temperature. Total phenolic and
flavonoid contents of the crude methanol extract was determined using standard methods. The
antioxidant activity of the crude methanol extract, fractions, and fixed oil was evaluated using
the 2,2-diphenyl-1-picryl hydrazyl (DPPH) free radical scavenging assay. Total polyphenolic
and flavonoid contents determination revealed that L. dentata crude methanol extract have high
contents of polyphenols (27.43 mg GAE/g), and flavonoids (20.62 mg QE/g). The ethyl acetate
fraction of L. dentata exhibited the highest antioxidant activity with IC50 value of 16.41 ± 0.11
µg/mL as measured by the DPPH radical scavenging assay. The n-butanol extract also
demonstrated notable antioxidant activity with IC50 value of 42.32 ± 0.86 µg/mL. The fixed oil
extracted from L. dentata aerial parts demonstrated mild antioxidant activity, with IC50 of 414.2
mg/mL. The findings from this study have shown that Lavandula dentata aerial parts contains
bioactive compounds with antioxidant potentials.
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