Phytochemical Profiling of Basella alba Using Gas chromatography-Mass Spectrometry

Dayo R. Omotoso; Victoria O. Olubowale; Faith M. Aina; Oore-Oluwapo O. Daramola

doi:10.26538/tjnpr/v8i6.36

Authors

Dayo R. Omotoso Department of Human Anatomy, Faculty of Basic Medical Sciences, Redeemer’s University, Ede, Nigeria
Victoria O. Olubowale Department of Human Anatomy, Faculty of Basic Medical Sciences, Redeemer’s University, Ede, Nigeria
Faith M. Aina Department of Human Anatomy, Faculty of Basic Medical Sciences, Redeemer’s University, Ede, Nigeria
Oore-Oluwapo O. Daramola Department of Human Physiology, Faculty of Basic Medical Sciences, Redeemer’s University, Ede, Nigeria

DOI:

https://doi.org/10.26538/tjnpr/v8i6.36

Keywords:

Mass spectrometry, Gas chromatography, Phytochemicals, Basella alba

Abstract

The therapeutic activities of medicinal plants have been associated with their constituent bioactive compounds called phytochemicals. The phytochemicals of methanol and aqueous leaf extracts of Basella alba were assessed using gas chromatography-mass spectrometry technique and pharmacological potential of the phytochemicals were elucidated. The results showed the presence of 8-Methyl-6-nonenoic acid, Valeric acid, but-3-yn-2-yl ester, 3-Decyne, 2-Butynedioic acid, Benzene, propyl-, 5-Ethyl-2-furaldehyde, 2-Pyrazoline, Furan, 3-methyl-, Caryophyllene oxide, Hexadecanoic acid methyl ester, 6-Octen-1-ol, 3,7-dimethyl- and trans-Geranylgeraniol in the methanol extract. Naphthalene, 1,2,3,4-tetrahydro-, Tetradecanoic acid, 1,5-Heptadiyne, 2-Pentadecanone, 6,10,14-trimethyl, 1,2Benzenedicarboxylic acid,1-Tetradecanol, Heptyl triacontyl ether, Pentadecanoic acid, n-Hexadecanoic acid, Cyclohexadecane, 9-Octadecenoic acid, Trichloroacetic acid, Cyclohexaneethanol, Heptadecanoic acid, 1-Octadecene, 1-Hexadecanol, and 1-Hexadecanol, 3,7,11,15-tetramethyl were identified in the aqueous extract. Some of the pharmacological properties of the identified phytochemicals include: antioxidant, anticancer, antimicrobial, antiproliferative, anti-inflammatory and neuroprotective effects. The findings derived from this study hereby elucidate the therapeutic value of the plant especially the aqueous extract which contained more phytochemicals with more prominent antioxidant effects. Hence, B. alba plant could serve as a veritable source of therapeutic agent for treatment and management of diseases.

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