A Mini Review on Botany, Phytochemistry, and Bioactivities of Jatropha podagrica Hook. (Euphorbiaceae)
Main Article Content
Abstract
Jatropha podagrica Hook., a member of the Euphorbiaceae family and known as “Dầu lai có củ” in Vietnamese, has a rich traditional use in treating constipation, skin infections, jaundice, and fever. The plant's chemical profile includes flavonoids, coumarins, phenolic acids, diterpenoids, peptides, and steroids. Numerous studies have highlighted the diverse biological effects of Jatropha podagrica, encompassing antibacterial and anticancer properties, antioxidant activity, insecticidal effects, muscle relaxation, and hypotensive activity. Despite its promising medicinal attributes, Jatropha podagrica remains underutilized, largely due to a lack of awareness. This review aims to offer an up-to-date and comprehensive exploration of the botany, phytochemistry, and bioactivities of Jatropha podagrica. To compile this information, searches were conducted on scientific databases such as Google Scholar, Elsevier, Springer and PubMed. In conclusion, Jatropha podagrica, with its diverse bioactive compounds, emerges as a valuable resource for addressing various health conditions.
Downloads
Article Details
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
How to Cite
References
Ghali W, Vaudry D, Jouenne T, Marzouki MN. Assessment of cyto-protective, antiproliferative and antioxidant potential of a medicinal plant Jatropha podagrica. Ind. Crops Prod. 2013;44:111-118.
Sharma SK, Singh H. A review on pharmacological significance of genus Jatropha (Euphorbiaceae). Chin. J. Integr. Med. 2012;18:868-880.
Dehgan B. Comparative anatomy of the petiole and infrageneric relationships in Jatropha (Euphorbiaceae). Am. J. Bot. 1982;69(8):1283-1295.
Aiyelaagbe OO, Adesogan K, Ekundayo O, Gloer JB. Antibacterial diterpenoids from Jatropha podagrica Hook. Phytochemistry 2007;68(19):2420-2425.
Devappa RK, Makkar HP, Becker K. Jatropha toxicity - a review. J. Toxicol. Environ. Health, Part B. 010;13(6):476-507.
Sabandar CW, Ahmat N, Jaafar FM, Sahidin I. Medicinal property, phytochemistry and pharmacology of several Jatropha species (Euphorbiaceae): a review. Phytochemistry. 2013;85:7-29.
Bhaskarwar BH, Itankar PR, Fulke AB. Evaluation of antimicrobial activity of medicinal plant Jatropha podagrica (Hook). Rom. Biotech. Let. 2008;13(5):3873-3877.
Aiyelaagbe OO, Adesogan EK, Ekundayo O, Hassanali A. Antifeedant activity of Jatropha podagrica roots. Fitoterapia. 1998;69(2):175-176.
Aiyelaagbe OO, Gloer JB. Japodic acid, a novel aliphatic acid from Jatropha podagrica Hook. Rec. Nat. Prod. 2008;2(4):100-106.
Liu WW, Zhang Y, Yuan CM, Yu C, Ding JY, Li XX, Hao XJ, Wang Q, Li SL. Japodagricanones A and B, novel diterpenoids from Jatropha podagrica. Fitoterapia. 2014;98:156-159.
Van den Berg AJ, Horsten SF, Kettenes-van den Bosch JJ, Beukelman CJ, Kroes BH, Leeflang BR, Labadie RP. Podacycline A and B, two cyclic peptides in the latex of Jatropha podagrica. Phytochemistry. 1996;42(1):129-33.
Silva CR, Fröhlich JK, Oliveira SM, Cabreira TN, Rossato MF, Trevisan G, Froeder AL, Bochi GV, Moresco RN, Athayde ML, Ferreira J. The antinociceptive and antiinflammatory effects of the crude extract of Jatropha isabellei in a rat gout model. J. Ethnopharmacol. 2013;145(1):205-213.
Abdelgadir HA, Van Staden J. Ethnobotany, ethnopharmacology and toxicity of Jatropha curcas L. (Euphorbiaceae): A review. South Afr. J. Botany. 2013;88:204-218.
Falodun A, Imieje V, Erharuyi O, Ahomafora JJ, Akunyuli C, Udu-Cosi AA, Theophilus O, Ali I, Albadry M, Fasinu P, Hamann MT. Isolation of diterpenoids from Jatropha podagrica against hepatitis C virus. J. Afr. Assoc. Physiol. Sci. 2014;2(1):21-25.
Kolawole OS, Jimoh MA, Yakubu F, Chukwuma EC. Taxonomic value of the leaf micro-morphology and quantitative phytochemistry of Jatropha integerrima Jacq. and Jatropha podagrica Hook. (Euphorbiaceae)-known horticultural plants in Nigeria. Anal. Biol. 2017;39:55-62.
Irvine FR. Woody Plants of Ghana 2nd edn, Oxford University Press, London. 1961.
Aiyelaagbe OO, Adesogan EK, Ekundayo O, Adeniyi BA. The antimicrobial activity of roots of Jatropha podagrica (Hook). Phytother. Res. 2000;14(1):60-62.
Sanni SB, Behm H, Beurskens PT, Adesogan EK & Durodola JI. The crystal and molecular structure of 1R, 3S, 5S, 10R,- 3, 6, 6, 10, 14,-penta methyltricyclo [10.3.0.0] pentadeca-11,14-diene-1,10-dihydroxy-2,13-dione (Japodagrol). J. Crystallogr. Spectrosc. Res.1988;18:575-
Odebiyi OO. Steroids and flavonoids from Jatropha podagrica stem bark. Fitoterapia. 1985; 56:302–303.
Ee GC, Lim CK, Taufiq-Yap YH, Go R. Ferulic acid ester from Jatropha podagrica (Euphorbiaceae). M. J. Chem. 2005;7:45-48.
Rumzhum NN, Sohrab MH, Al-Mansur MA, Rahman MS, Hasan CM, Rashid MA. Secondary metabolites from Jatropha podagrica Hook. J. Phys. Sci. 2012;23:29-37.
Institute of Botany, Chinese Academy of Sciences, Flora Reipublicae Popularis Sinicae, Beijing: Science Press, 44.
Marzouk M, Khalifa SM, Ahmed AH, Metwaly AM, Sh Mohammed H, Taie HAA. LC/HRESI-MS/MS screening, phytochemical characterization, and in vitro antioxidant and cytotoxic potential of Jatropha integerrima Jacq. extracts. Bioorg. Chem. 2023;140:106825.
Abreu IC, Marinho AS, Paes AM, Freire SM, Olea RS, Borges MO, Borges AC. Hypotensive and vasorelaxant effects of ethanolic extract from Jatropha gossypiifolia L. in rats. Fitoterapia. 2003;74(7-8):650-7.
Drafor G, Duah E, Ankamah NA, Kpene GE, Mante PK. Investigating the anticonvulsant properties of aqueous ethanolic extracts of the leaves, roots, and fruits of Jatropha gossypifolia L. (Euphorbiaceae). Adv. Pharmacol. Pharm. Sci. 2021;2021:5547353.
Yuan HT, Li QF, Tian T, Zhang CY, Huang ZQ, Fan CX, Mei K, Zhou J, Zhai XX, Li SB, Zhu JY. Lathyrane diterpenoids from Jatropha podagrica and their antitumor activities in human osteosarcoma cells. Nat. Prod. Res. 2021;35(23):5089-5095.
Zhang D, Yu J, Zhang Z, Liang Y, Tang Z, Wang Z. Structure, absolute configuration and biological evaluation of a new labdane diterpenoid from Jatropha podagrica. Rec. Nat. Prod. 2020;14(5):360.
Cavalcante NB, da Conceição Santos AD, da Silva Almeida JR. The genus Jatropha (Euphorbiaceae): A review on secondary chemical metabolites and biological aspects. Chem. Biol. Interact. 2020;318:108976.
Lin CH, Huang JL, Zhang L, Hai-Yan TI, Sheng YI. Jatrogricaine A: a new diterpenoid with a 5/6/6/4 carbon ring system from the stems of Jatropha podagrica. Chin. J. Nat. Med. 2019;17(4):298-302.
Thomas S. Pharmacognostic and phytochemical constituents of leaves of Jatropha multifida Linn. and Jatropha podagrica Hook. J. Pharmacog. Phytochem. 2016;5(2):243-246.
Odebiyi OO. Isolation of a new flavone and some essential oils with antimicrobial and antifungal properties from the stem bark of Jatropha podagrica. Planta Med. 1982;45(07):138.
Yin Z, Zhang J, Kang W. Volatile Composition of Jatropha podagrica seeds and flowers. Chem. Nat. Comp. 2017;53:165-166.
Ojewole JA, Odebiyi OO. Neuromuscular and cardiovascular actions of tetramethylpyrazine from the stem of Jatropha podagrica. Planta Med. 1980;38(04):332-338.
Boonmee S, Iwasaki A, Suenaga K, Kato-Noguchi H. Identification of 6, 7-dimethoxychromone as a potent allelochemical from Jatropha podagrica. Nat. Prod. Com. 2018;13(11):1934578X1801301126.
Minh TN, Xuan TD, Tran HD, Van TM, Andriana Y, Khanh TD, Quan NV, Ahmad A. Isolation and purification of bioactive compounds from the stem bark of Jatropha podagrica. Molecules. 2019;24(5):889.
Odebiyi OO. Antibacterial property of tetramethyl-pyrazine from the stem of Jatropha podagrica. Planta Med. 1980;38(02):144-146.
Zhang X, Zhang M, Su X, Huo C, Gu Y, Shi Q. Chemical constituents of the plants from genus Jatropha. Chem. Biodiver. 2009;6(12):2166-2183.
Adewunmi CO, Odebiyi OO. In vitro schistosomicidal activity of tetramethylpyrazine from Jatropha podagricaHook. stem bark. Int. J. Crude Drug Res. 1985;23(3):119-120.