Mechanisms of Vasodilation Induced by Medicinal Plants: A Mini-Review

Anthony B. Ebeigbe * and Olufunke O. Arishe
Department of Physiology, College of Medical Sciences, University of Benin, Benin City, Nigeria
Corresponding Author: [email protected]; Tel: +234 802 622 9266
Recieved Date: August 04, 2017; Accepted Date: September 08, 2017; Published Date: 09 September 2017
Citation: Ebeigbe AB, Arishe OO. Mechanisms of Vasodilation Induced by Medicinal Plants: A Review. Tropical Journal of Natural Product Research 2017; 1(3):97-99.
Copyright: © 2017 Ebeigbe and Arishe. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Medicinal plants are commonly used for the treatment of cardiovascular diseases; however, there is a paucity of information on their mechanisms of action. Some antihypertensive medicinal plants have been reported to act like vasodilator drugs, through a variety of cell signalling processes involving modulation of endothelial and vascular smooth muscle functions. Since endothelial dysfunction as well as increased peripheral vascular resistance are known to be associated with hypertension, this review highlights key cell signalling processes involving endothelium-derived factors as well as cellular Ca2+ homeostasis that may be used to characterize the vasodilator actions of medicinal plants.

Keywords: Medicinal plants, Vasodilation, Endothelium, Smooth muscle
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ISSN: 2616-0684 (Print)
ISSN: 2616-0692 (Online)
DOI: 10.26538/tjnpr
Index Copernicus Value (ICV) for 2017: 59.83
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