Antioxidant Activity of Uncaria Gambir (Hunter) Roxb Extracts

Mutia D. Hidayati* and Arief Rahmatulloh
Department of Chemical Engineering, Politeknik Negeri Malang, Malang, Indonesia
Corresponding Author: [email protected]; Tel: +62-341-404424
Recieved Date: 22 May 2022; Accepted Date: 29 August 2022; Published Date: 03 September
Citation: Hidayati MD and Rahmatulloh A. Antioxidant Activity of Uncaria Gambir (Hunter) Roxb Extracts. Trop J Nat Prod Res. 2022; 6(8):1215-1218. http://www.doi.org/10.26538/tjnpr/v6i8.9
Copyright:
© 2022 Hidayati and Rahmatulloh. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
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ABSTRACT

Uncaria Gambir is a popular plant in Southeast Asia, used traditionally for healing various diseases. Pharmacologically, U. Gambir has many potentials. This study aimed to investigate the antioxidant activities of U. Gambir stem extracts (methanol, ethyl acetate and n-hexane) using DPPH (2,2-diphenyl-2-2-picrylhydrazyl) and ABTS (2,2’-azinobis (3-ethylbenzothiazole-6-sulfonic acid) methods. The results of this study show that methanol extract has the highest antioxidant activity in the DPPH assay with IC50 value of 9.71 µg/mL. In addition, it has the highest ABTS activity with the IC50 value of 6.63 µg/mL. This study showed that the methanol extract of U. Gambir can potentially be used as an antioxidant.

Keywords: Antioxidant, ABTS, DPPH, Uncaria gambir (Hunter) Roxb, Stem Extracts. 
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ISSN: 2616-0684 (Print)
ISSN: 2616-0692 (Online)
DOI: 10.26538/tjnpr
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