Phytochemical Profile and in vitro Sun-Protective Activity of Polyalthia longifolia (Sonn.) Thwaites Bark Extracts

Bhawana Bhatt*, Himanshu Chaurasia, Ranjit Singh, Sudhakar Kaushik
Adarsh Vijendra Institute of Pharmaceutical Sciences, Shobhit University, Gangoh, Saharanpur, Uttar Pradesh, India
Corresponding Author: [email protected]; Tel: +917252855994
Recieved Date: 09 October 2021; Accepted Date: 20 August 2022; Published Date: 03 September
Citation: Bhatt B, Chaurasia H, Singh R, Kaushik S. Phytochemical Profile and in vitro Sun-Protective Activity of Polyalthia longifolia (Sonn.) Thwaites Bark Extracts. Trop J Nat Prod Res. 2022; 6(8):1174-1177.
© 2022 Bhatt et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
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Sunscreen formulations are required to protect the skin from damaging ultraviolet radiation, which causes irritation, erythema (sunburn), generalized or localized hyperpigmentation (tanning), skin malignancies, immunosuppression, and inflammation. Efficacious, high-quality products are in high demand currently. There are some sunscreens with broad spectrum UV protection that are inexpensive, safe, and herbal. The present study was conducted to investigate the phytochemical profile and sun-protective properties of Polyalthia longifolia (Sonn.) Thwaites extracts. The bark of P. longifolia was extracted with water, ethanol, and petroleum ether by the cold maceration method. A preliminary phytochemical screening on the P. longifolia bark extracts was conducted. The in vitro sun-protective activity of the different P. longifolia extracts was assessed by determining the sun protection factor (SPF) using the UV spectroscopic technique. The results of the phytochemical screening revealed the presence of flavonoids, phenols, and tannins in all the P. longifolia bark extracts. The SPF values of the different extracts were observed to be 5.24±0.002, 1.07±0.009, and 1.01±0.012 for the ethanolic, petroleum ether, and water extracts, respectively. The findings of this study suggest that the aqueous, ethanol, and petroleum ether extracts of P. longifolia bark could be used to make photoprotective formulations that have additive or synergistic effects in a variety of combinations and quantities

Keywords: Hyperpigmentation, Mansur equation, Polyalthia longifolia, Sunscreen, Ultraviolet radiation.
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ISSN: 2616-0684 (Print)
ISSN: 2616-0692 (Online)
DOI: 10.26538/tjnpr
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