Evaluation of Toxicity of the Ethanol Extract of Euphorbia antiquorum L. in Drosophila melanogaster

Tran T. Men*, Nguyen H. Son, Huynh H. Phien

1College of Natural Sciences, Can Tho University, Can Tho city 94000, Vietnam
2Faculty of Basic Sciences, Vinh Long University of Technology Education, Vinh Long city 85000, Vietnam

Corresponding Author: [email protected]; Tel: +84.907.416.657
Recieved Date: 13 June 2022; Accepted Date: 28 July 2022; Published Date: 04 August 2022
Citation: Men TT, Son NH, Phien HH. Evaluation of Toxicity of the Ethanol Extract of Euphorbia antiquorum L. in Drosophila melanogaster. Trop J Nat Prod Res. 2022; 6(7): 1140-1145. http://www.doi.org/10.26538/tjnpr/v6i7.17
© 2022 Men et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Visit for more related articles at  Tropical Journal of Natural Product Research


Many plant extracts exhibit insecticidal activity and are considered an environmentally friendly method for pest management. They act through various effects on the target insects, including repellency, growth inhibition, and structural and physiological changes. This study was carried out to evaluate the potential of Euphorbia antiquorum L. to inhibit the growth and development of fruit flies. The plant extract exerted a great influence on the growth and development of Drosophila melanogaster fruit flies through the different survey criteria, such as the rate of pupation, larval formation, the energy storage composition of carbohydrates, proteins, lipids, and levels of enzymes belonging to the esterase group (AchE, ?-carboxyl, and ?-carboxyl) and phosphatase (AcP and AkP) of adult flies after 14 days surveying. At a 15 mg/mL concentration, the extract affected the growth and the development of fruit flies; the number of pupated larvae was 2.25 times lower than that of the control treatment as a standard food; 80.99% of the flies died at the pupal stage and were not able to develop to the adult stage. Total flavonoid and polyphenol content were determined to be 466±6.35 mg GAE/g extract and 198±2.33 mg QE/g extract, respectively. From the The present findings show that Euphorbia antiquorum L. has a potential for use as an insecticidal

Keywords: Drosophila melanogaster, enzyme inhibition, extract, Euphorbia antiquorum L., inhibit.
Back to Articles

ISSN: 2616-0684 (Print)
ISSN: 2616-0692 (Online)
DOI: 10.26538/tjnpr
Index Copernicus Value (ICV) for 2017: 59.83
Scopus citescore 0.3 (2020)

Indexing & Abstracting

citescore 0.3 (2020)

j-gate logo

International Innovative Journal Impact Factor

African Index Medicus


Index Copernicus International

Creative Commons License
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License

Crossref Content Registration logo

WorldCat Discovery Service

Geneva Foundation for Medical Education and Research