The Reasons Behind the Salubrious of Colostrum on the Cognitive Functions: A Systematic Review

Marwan S.M. Al-Nimer1,2*, Ahmed Kh. Al-Basri2, Dinara Satrmbekova3, Ubaidilla M. Datkhayev3

1Emeritus Professor of Therapeutics, College of Medicine, University of Diyala, 32001-Baqubah, Iraq
2Department of Pharmacy, Al-Kut University College, 52001-Wasit, Iraq 
3Al Farabi Kazakh National University Disabled, Almaty, Kazakhstan

Corresponding Author: [email protected] ; Tel: +964 790 26 00291
Recieved Date: 10 April 2021; Accepted Date: 3 August 2022; Published Date: 04 August 2022
Citation: Al-Nimer MSM, Al-Basri AK, Satrmbekova D, Datkhayev UM. The Reasons Behind the Salubrious of Colostrum on the Cognitive Functions: A Systematic Review. Trop J Nat Prod Res. 2022; 6(7): 1057-1066.
© 2022 Al-Nimer et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
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Bovine colostrum (BC) is rich in many vitamins, minerals, and antioxidant substances.  Its supplementation provides health benefits, particularly for athletes. This systematic review was carried out to update on the benefit of BC or its formulations (e.g., colostrinin) on the cognitive functions or their related biomarkers in experimental and human studies.  Full texts or abstracts of 219 articles as reports of narrative or systematic reviews, randomized controlled clinical trials, observational studies, and experimental studies (in vitro, ex vivo, and in vivo) were included after searches in PubMed, Europe PMC, Google scholar databases. The full texts of eligible articles (25 articles) were assessed and their results were summarized in different categories according to the study design. Bovine colostrum or its related formulations have been shown to be useful as they improve cognitive functions and their biomarkers. Compatible results were observed in experimental and human studies. Further studies are mandatory to elucidate the rationale for using (BC) in healthy subjects and patients with impaired of cognitive functions

Keywords: Bovine colostrum, Colostrinin, Cognitive functions, Clinical studies, Experimental studies.
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ISSN: 2616-0684 (Print)
ISSN: 2616-0692 (Online)
DOI: 10.26538/tjnpr
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