GC-MS Analysis of Phytoconstituents in Fractions of Corydalis adiantifolia

Iftikhar Ali¹*, Saleha S. Khan², Ajmal Khan³, Zulfiqar Ali¹, Huma A. Bhatti⁴, Jean J.K. Bankeu⁵, Viqar U. Ahmad⁴

¹Department of Chemistry, Karakoram International University, 15100-Gilgit, Gilgit-Baltistan, Pakistan.

²Department of Chemistry, Sardar Bahadur Khan Women University, Quetta, Balochistan, Pakistan.

³UoN Chair of Oman’s Medicinal Plants and Marine Natural Products, University of Nizwa, Nizwa, Sultanate of Oman.

⁴HEJ Research Institute of Chemistry, University of Karachi, Karachi-75270, Pakistan.

⁵Department of Chemistry, Faculty of Science, The University of Bamenda, P.O. Box 39, Bambili, Cameroon.

Corresponding Author: [email protected]; Tel: +92-3339665739

Recieved Date: May 16, 2018; Accepted Date: June 05, 2018; Published Date: 07 June 2018

Citation: Ali I, Khan SS, Khan A, Ali Z, Bhatti HA, Bankeu JJK, Ahmad VU. GC-MS Analysis of Phytoconstituents in Fractions of Corydalis adiantifolia. Trop J Nat Prod Res. 2018; 2(6):282-289.  https://doi.org//10.26538/tjnpr/v2i6.5

Copyright: © 2018 Ali et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

ABSTRACT

Corydalis adiantifolia Hook.f. & Thomson (Fumariaceae) is a herb known as shampoo (Balti) in Shigar valley, Baltistan. In addition, other Corydalis species have been reported as antidiabetic, anticancer, anti-inflammatory, and analgesic. Phytochemical study has exhibited the presence of mostly alkaloids in various Corydalis species. C. adiantifolia, to the best of our knowledge, has not been investigated so far for any kind of phytochemical analysis. In our present study, the n-hexane, dichloromethane and ethyl acetate fractions of the methanol extract of Corydalis adiantifolia Hook.f. & Thomson (Fumariaceae) were studied through gas chromatography-mass spectrometry (GC-MS) analysis. A number of phytoconstituents are found in these fractions. The phytoconstituents reported in our present study include different esters, long chain alcohols, ketones, aldehydes and carboxylic acids, phenols, etc. More interestingly, different alkaloids are being reported in this study. Protopine, hydrastine, hydrastinine, oxyhydrostinine, (RS)-stylopine, oxoberberine, D-bicuculline and norsanguinarine are the main alkaloids reported through GC-MS in different fractions of C. adiantifolia.