Parquetina nigrescens Species: A Concise Review of Phytochemistry and Pharmacology

Omowumi T. Kayode1*, Nkechinyere J. Ohanaka2, Fehintolu J. Femi-Olabisi1, Anthonia O. Agboola3, Elizabeth O. Oyebanji1
1Department of Biochemistry, College of Basic and Applied Sciences, Mountain Top University, Ogun State, Nigeria
2Department of Biochemistry, Faculty of Natural and Applied Sciences, Nile University of Nigeria, Abuja, Nigeria
3Biochemistry Unit, Department of Biological Sciences, Wesley University, PMB 507, Ondo, Nigeria

Corresponding Author: [email protected]; Tel: +2348037802662
Recieved Date: 16 September 2021; Accepted Date: 23 April 2022; Published Date: 03 May
Citation: Kayode OT, Ohanaka NJ, Femi-Olabisi FJ, Agboola AO, Oyebanji EO. Parquetina nigrescens species: A Concise Review of Phytochemistry and Pharmacology. Trop J Nat Prod Res. 2022; 6(4): 454-461 http://www.doi.org/10.26538/tjnpr/v6i4.1
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© 2022 Kayode et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
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ABSTRACT

Parquetina nigrescens species is a member of the Periploceaceae family, found majorly across countries in Africa. It has myriads of folkloric uses till date in this region. It is sometimes used in combination with other plants traditionally to treat several ailments such as inflammation, insanity, diarrhoea, skin infections, gonorrhoea, menstruation aberrations, helminthic infections, sexual disorders and some other complicated disorders. Based on our search, there is no review article to date on the authenticated biological activities of P. nigrescens, despite numerous researches. This review aims at presenting a novel summary of established pharmacological properties and mechanisms of action of Parquetina nigrescens.
Several bioactive components such as flavonoids, saponins, alkaloids, tannins, free and bound anthraquinones, phlobatinins, terpenoid, cardenolides, triterpenes etc. have been derived from chemical analysis of Parquetina nigrescens, these play important roles in the detected pharmacological activities of the plant such as anti-diabetic, anti-cancer, anti-inflammatory, anti-oxidant, anti-diarrhoea, anti-sickling, anti-neurotoxic, anti-apoptotic anti-microbial, anti-nociceptive, antiulcer, aphrodisiac and anti-neurodegenerative properties as reported by several researchers. Thus, the plant has a promising outlook for drug discovery and development.

Keywords: Parquetina nigrescens, Bioactive Component, Pharmacologic Activity, Phytochemical.
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ISSN: 2616-0684 (Print)
ISSN: 2616-0692 (Online)
DOI: 10.26538/tjnpr
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