Isolation and Characterization of Some Flavonoids from the Leaves of Globimetula braunii (Loranthaceae) Growing on Terminalia catappa L. (Combretaceae)

Suleiman Danladi^1,2*, Mohammed I. Sule², Musa A. Muhammad², Abdullahi H. Yaro³

¹Department of Pharmaceutical and Medicinal Chemistry, Faculty of Pharmaceutical Sciences, Bayero University, Kano, Nigeria

²Department of Pharmaceutical and Medicinal Chemistry, Faculty of Pharmaceutical Sciences, Ahmadu Bello University, Zaria, Nigeria

³Department of Pharmacology and Therapeutics, Faculty of Pharmaceutical Sciences, Bayero University, Kano, Nigeria

Corresponding Author: [email protected]; Tel: +2348062228858

Recieved Date: 20 April 2021; Accepted Date: 12 December 2021; Published Date: 04 January

Citation: Danladi S, Sule MI, Muhammad MA, Yaro AH. Isolation and Characterization of Some Flavonoids from the Leaves of Globimetula braunii (Loranthaceae) Growing on Terminalia catappa L. (Combretaceae). Trop J Nat Prod Res. 2021; 5(12): 2133-2136 http://www.doi.org/10.26538/tjnpr/v5i12.15

Copyright:

Copyright: © 2021 Danladi et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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ABSTRACT

Isolation and purification of natural products from medicinal plants are important components of drug development. Many important phytochemical compounds have been isolated from medicinal plants and are used as active therapeutic substances. This study aimed to isolate and characterize some of the phytochemical compounds present in the n-butanol soluble fraction of the ethanol extract of the leaf of Globimetula braunii (Loranthaceae) growing on Terminalia catappa. The dried pulverized leaf of Globimetula braunii was extracted with 90% ethanol using cold maceration. The ethanol leaf extract was partitioned using n-hexane, chloroform, ethyl acetate and n-butanol. The n-butanol fraction was subjected to silica gel column chromatography. The major fractions were further purified using Sephadex gel filteration. Three flavonols; rhamnetin, quercetin and rhamnetin-3-O-?-L-rhamnopyranoside were isolated. The structures of these compounds were established by spectroscopic analysis including 1D and 2D NMR. This is the first report of the isolation of these compounds from Globimetula braunii (Loranthaceae) growing on Terminalia catappa.