Aphrodisiac Effect of Methanol Hypocotyls Extracts of Borassus aethiopum Mart. in Male Wistar Rats

Mansur A. Ramalan*, Adamu B. Shuaibu, Umar S. Abdussalam, Abdullahi H. Yaro

Department of Pharmacology and Therapeutics, Bayero University, Kano, Nigeria
Corresponding Author: [email protected]; Tel: +2348036783737
Recieved Date: 19 March 2021; Accepted Date: 23 October 2021; Published Date: 03 November
Citation: Ramalan MA, Shuaibu AB, Abdussalam US, Yaro AH. Aphrodisiac Effect of Methanol Hypocotyls Extracts of Borassus aethiopum Mart. in Male Wistar Rats. Trop J Nat Prod Res. 2021; 5(10): 1852-1858. http://www.doi.org/10.26538/tjnpr/v5i10.24
© 2021 Ramalan et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Visit for more related articles at  Tropical Journal of Natural Product Research


Borassus aethiopum is a tropical plant found in most parts of West Africa. The fruits and hypocotyl are used in traditional herbal medicine for the treatment of various diseases (malaria, bronchitis, skin infections and infertility) and nutritional purposes. In many parts of Nigeria especially in Northern Nigeria, it is used as an aphrodisiac agent in males. This study evaluated the aphrodisiac effect of the methanol extract of the hypocotyl of Borassus aethiopum in male Wistar rats. Adult male Wistar rats were divided into five groups and administered orally with the plant extract at doses of 250, 500 and 1000 mg/kg body weights. Sildenafil citrate (5 mg/kg) and distilled water (1 mL/kg) were administered orally, and served as positive and negative controls, respectively. The acute toxicological evaluation of the plant extract was based on behavioural changes and mortality. Sexual behavioural parameters (mounting and intromission frequencies, and ejaculatory latencies) were observed on days 1, 7 and 28. Serum testosterone, luteinizing hormone (LH), follicle-stimulating hormone (FSH) and gonadotrophin releasing hormones (GnRH) were measured. Acute toxicity studies of the plant extract did not show any behavioural changes in the animals and there was no mortality.  The extract significantly increased mounting and intromission frequencies (p<0.05) and decreased mounting and intromission latencies in a dose-dependent manner on days 1, 7 and 28 (p<0.05).  It also prolonged ejaculatory latency. The extract was also noted to increase GnRH, serum testosterone and gonadotrophins. The results suggest that the methanol hypocotyl extract of Borassus aethiopum possess aphrodisiac properties.

Keywords: Aphrodisiac, Borassus aethiopum, Male sexual behaviour, Testosterone, Traditional medicine.
Back to Articles

ISSN: 2616-0684 (Print)
ISSN: 2616-0692 (Online)
DOI: 10.26538/tjnpr
Index Copernicus Value (ICV) for 2017: 59.83
Scopus citescore 0.3 (2020)

Indexing & Abstracting

citescore 0.3 (2020)

j-gate logo

International Innovative Journal Impact Factor

African Index Medicus


Index Copernicus International

Creative Commons License
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License

Crossref Content Registration logo

WorldCat Discovery Service

Geneva Foundation for Medical Education and Research