Phytochemical Constituents and Antimicrobial Activity of Elaeocarpus sphaericus Schum Seed Extract

Cicilia N. Primiani1*, Pujiati Pujiati1, Mohammad A. Setiawan2




1Department of Biology Education, Universitas PGRI Madiun, Madiun, East Java, Indonesia
2Department of Chemical Engineering, Universitas PGRI Madiun, Madiun, East Java, Indonesia


Corresponding Author: [email protected]; Tel: +62 815-5654-1989
Recieved Date: 25 June 2021; Accepted Date: 19 October 2021; Published Date: 03 November
Citation: Primiani CN, Pujiati, Setiawan MA. Phytochemical Constituents and Antimicrobial Activities of Elaeocarpus sphaericus Schum Seed Extract. Trop J Nat Prod Res. 2021; 5(10): 1775-1781. http://www.doi.org/10.26538/tjnpr/v5i10.13
Copyright:
© 2021 Primiani et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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ABSTRACT

The use of medicinal plants in health care services has tremendously increased. Medicinal plants contain bioactive compounds that are very important in biological activities and may possess antioxidant, anticancer, and antimicrobial properties. Therefore, this study was aimed at identifying the phytochemical constituents of Elaeocarpus sphaericus Schum (genitri) seed extract and determining its antibacterial activity. E. sphaericus seeds were obtained, dried, and prepared into powder form. The seed powder was extracted with methanol. Phytochemical analysis was conducted on the methanol seed extract using the Liquid Chromatography-Mass Spectrometry (LC-MS) technique. Antibacterial sensitivity testing was carried out with the agar disk diffusion method. The result of the phytochemical screening revealed that E. sphaericus seed extract contains 72 compounds which include dicarboxylic acid, aromatic acid, ester, glucose, coumarin, alkaloid, flavonoid, tannin, glycoside, steroid, terpenoid, quinone, and coumestan. Each phytochemical compound varies in composition, with caffeic acid (3.12%) being the highest. The antibacterial sensitivity testing of the 15 and 40% E. sphaericus seed extracts against E. coli indicated inhibition zone diameters of 7.25 and 7.75 mm, respectively, while values of 7.5 and 9 mm, respectively were recorded for L. acidophilus. Also, the antibacterial activity of the seed extract was found to be concentration-dependent. The findings of this study reveal that E. sphaericus seed extract contain several phytochemical compounds and has antibacterial activity against E. coli and L. acidophilus, thereby making it a potential antibacterial agent.

Keywords: Antibacterial, Elaeocarpus sphaericus Schum, Metabolites, Phytochemicals.
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ISSN: 2616-0684 (Print)
ISSN: 2616-0692 (Online)
DOI: 10.26538/tjnpr
Index Copernicus Value (ICV) for 2017: 59.83
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