TY - JOUR AU - Rasidah, Rasidah AU - Maurizka, Icha S. AU - Aulianshah, Vonna AU - Munira, Munira AU - Zakiah, Noni AU - Handayani, Rini PY - 2022/12/30 Y2 - 2024/03/28 TI - Repellent Activity of Lotion of Essential Oils from Piper betle Linn and Cymbopogon nardus [L.] Rendle: http://www.doi.org/10.26538/tjnpr/v6i12.20 JF - Tropical Journal of Natural Product Research (TJNPR) JA - TJNPR VL - 6 IS - 12 SE - Articles DO - UR - https://tjnpr.org/index.php/home/article/view/1409 SP - 2020-2024 AB - <p><span class="fontstyle0">Long term use of </span><span class="fontstyle0">N,N-diethyl-meta-toluamide (DEET) </span><span class="fontstyle0">in insect repellents can cause some effects such as mild irritation, itching, rash, urticaria, contact dermatitis, swelling and seizures. In addition, DEET can also contaminate aquatic environments. Because of these side effects, it is necessary to look for alternative repellents. </span><span class="fontstyle0">Betel leaves (</span><span class="fontstyle2">Piper betle </span><span class="fontstyle0">Linn</span><span class="fontstyle2">.</span><span class="fontstyle0">) and Citronella grass (</span><span class="fontstyle2">Cymbopogon nardus </span><span class="fontstyle0">[L.] Rendle) contain essential oils that repel insects. This study aimed to develop an effective, non-toxic, environmentally friendly, and biodegradable natural insect repellent by formulating a mosquito-repellent lotion from betel leaves and citronella grass essential oils. The betel leaves and citronella grass essential oils were formulated into a lotion with three concentrations (1, 5, 10% w/w). Evaluation of lotions stored at 1% (F1), 5% (F2), and 10% (F3) concentration was conducted in 7 cycles of freeze-thaw. Lotion quality was analyzed<br>for organoleptic, pH, viscosity, homogeneity, stability and skin sensitivity. </span><span class="fontstyle0">The evaluation results showed that the four lotion formulae were stable, did not cause skin irritation, were homogeneous, and had a pH of 7. The results of the centrifugation test showed that 1% lotion was stable, while 5% and 10% had phase separation. The protection against </span><span class="fontstyle2">Culex quinquefasciatus </span><span class="fontstyle0">mosquitoes at 1hr, 2hrs and 3hrs was 68.73%, 95.83% and 100%, respectively. </span><span class="fontstyle0">The repellent activity of lotions with betel leaves and citronella grass oils was concentration dependent.&nbsp;</span></p> ER -