Diseases Induced by Heavy Metal Exposure and their Ameliorative Phytochemicals: A Review

Abimbola P. Oluyori1*, Adejumoke A. Inyinbor1, Charity O. Aremu2, Omorefosa O. Osemwegie3, Awolesi Oluwafemi1, Temitope A. Ogunnupebi1
1Industrial Chemistry Programme, Physical Sciences Department, Landmark University, Omuaran, Kwara State, Nigeria
2Crop Science Programme, Agricultural Sciences Department, Landmark University, Omuaran, Kwara State, Nigeria
3Department of Microbiology, Landmark University, Omuaran, Kwara State, Nigeria

Corresponding Author: oluyori.abimbola@lmu.edu.ng; Tel: +2348038083231
Recieved Date: July 12, 2020; Accepted Date: September 18, 2020; Published Date: 03 October 2020
Citation: Oluyori AP, Inyinbor AA, Aremu CO, Osemwegie OO, Awolesi O, Ogunnupebi TA. Diseases Induced by Heavy Metal Exposure and their Ameliorative Phytochemicals: A Review. Trop J Nat Prod Res. 2020; 4(9):479-489 https://doi.org/10.26538/tjnpr/v4i9.1
Copyright: © 2020 Oluyori  et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
ABSTRACT

Indiscriminate disposal of refuse and industrial effluents have continued to introduce toxic chemicals into our environment. Most of these toxic wastes, particularly the heavy metals are colourless, hence, the silent access which they often gain into the human body via food and water. This has increasingly posed deleterious effects on public health globally in the twenty-first century. Relevant publications were primarily sourced from Science Direct (a major contributor to the Scopus database) using “heavy metals; toxicity; amelioration; herbs, treatment” as keywords. This article gives an overview of health risk factors, the pathogenic health effects of common heavy metals and the sustainable route to their amelioration using natural products with heavy metal chelating potential in different animal models. The incorporation of these herbs in diets and the direct therapeutic applications of crude plant extracts, fractions and isolates enhance the human defense system against the various diseases which are usually associated with the consumption of heavy metal contaminated food and water.

Keywords: Amelioration, Antioxidant, Herbs, Heavy Metal, Phytochemicals, Toxicity.
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