Boswellia carterii Birdwood Topical Microemulsion for the Treatment of Inflammatory Dermatological Conditions; a Prospective Study

Ahmed M. Omar1, Nagwa M. Ammar2, Rehab A. Hussein2*, Dina M. Mostafa3, Mona Basha3, Mahmoud F. Abdel Hamid1  
1Department of Dermatology, National Research Centre, Giza, Egypt
2Department of Pharmacognosy, National Research Centre, Giza, Egypt
3Department of Pharmaceutical Technology, National Research Centre, Giza, Egypt

Corresponding Author: rehaba.husein@yahoo.com; Tel: 002-01000955449
Recieved Date: July 29, 2020; Accepted Date: August 24, 2020; Published Date: 28 August 2020
Citation: Omar AM, Ammar NM, Hussein RA, Mostafa DM, Basha M, Hamid MFA. Boswellia carterii Birdwood Topical Microemulsion for the Treatment of Inflammatory Dermatological Conditions; a Prospective Study. Trop J Nat Prod Res. 2020; 4(8):372-377.  https://doi.org/10.26538/tjnpr/v4i8.9
Copyright: © 2020 Omar et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
ABSTRACT

Several dermatological conditions, such as acne, eczema and urticaria, underlie inflammation among its pathogenesis.  Boswellia carterii Bird. oleo-gum-resin has been extensively used in Ayurveda, Egyptian and Chinese traditional medicine for its anti-inflammatory activity. The aim of this study is to investigate the therapeutic potential of a topical microemulsion of B. carterii oleo-gum-resin standardized bioactive fraction on patients with acne, eczema and urticaria. This prospective study included 47 patients; 34 males and 13 females; 8 of which were suffering from acne, 29 from eczema and 10 from urticaria, receiving a topical dose twice daily from the standardized bioactive fraction of B. carterii oleo-gum-resin in the form of topical microemulsion. The number of acne lesions was significantly decreased in all study groups from basal to week 2 and from week 2 to week 4 of the study. Patients satisfaction was high in all the groups which further ascertained the improvement detected by the doctors visual inspection. In conclusion, topical microemulsion of B. carterii oleo-gum-resin standardized bioactive fraction is effective in the treatment of patients with acne, eczema and urticaria.

Keywords: Traditional medicine, Boswellia carterii Bird. Oleo-gum-resin, Topical Microemulsion, Acne.
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